NIAID Emerging and Re-emerging Infectious Diseases NIAID Bioinformatics Resource Centers NIAID Structural Genomic Centers Center for Structural Genomics of Infectious Disease
Seattle Structural Genomics Center for Infectious Disease

LemaA.00628.a: adenylate kinase, putative

Target Characteristics

from organism: Leishmania major Friedlin
most recent status: purified
center reference id: LemaA.00628.a
is community request: True
associated disease: Cutaneous leishmaniasis
NIH risk group: 2
is select agent: False
NIH priority
pathogens category:
unclassified

Ordering Clones & Proteins

If there are materials available for this target, they will be listed below. Materials can be ordered from SSGCID using the button in the "order material" column. Clicking the button will add the material to a virtual cart. You may order multiple materials at a time at no cost to you, as this contract is funded by NIAID. When you are ready to place your order, click the "Place Order" link which will appear in the top right corner of the page after you place your first item in your cart.

Clones*

CENTER
REFERENCE ID
DOMAIN/REGION
DESCRIPTION
INFO AA
START
AA
STOP
ORDER
MATERIAL
LemaA.00628.a.A1.GE34359 full length 1 220 GE34359
* SSGCID clones represent un-induced expression constructs which have been verified by sequencing from vector primers. Clones may contain a tag, such as N-term 6xHis. Get sequence information using the button in the "info" column.

Proteins

CENTER
REFERENCE ID
DOMAIN/REGION
DESCRIPTION
INFO AA
START
AA
STOP
ORDER
MATERIAL
LemaA.00628.a.A1.PW34969 full length 1 220

External Resources

Resource Reference ID
EuPathDB: TritrypDB:LmjF36.1360
OrthoMCL: OG5_138748
RefSeq: XP_001686708.1
UniProt: Q4Q1U0

Enzyme & Pathway Information

Pathway Pathway ID EC Number
superpathway of purine nucleotides de novo biosynthesis II DENOVOPURINE2-PWY 2.7.4.3
purine and pyrimidine metabolism P1-PWY 2.7.4.3
superpathway of histidine, purine, and pyrimidine biosynthesis PRPP-PWY 2.7.4.3
superpathway of adenosine nucleotides de novo biosynthesis II PWY-6126 2.7.4.3
superpathway of purine nucleotide salvage PWY66-409 2.7.4.3
adenosine ribonucleotides de novo biosynthesis PWY-7219 2.7.4.3
superpathway of adenosine nucleotides de novo biosynthesis I PWY-7229 2.7.4.3
superpathway of purine nucleotides de novo biosynthesis I PWY-841 2.7.4.3

Sequences

These sequences are the native gene sequence; sequences of constructs derived from these sequences may differ due to codon optimization or other protocols. To find the specific sequence of any material you may have ordered, click on the "more" button next to the name of that material.
AA Sequence
MPLFIILFGP PGSGKGTVSH LLVKEYGFVH LSAGNLLREE VLKKSPLGRR CAEIMSEGSL IPDELVVDLV CNRLSEQAVQ KHGILLDGFP RNLRQAEVLT ARGFKFDMMI FLDVSPEILL DRCLSRRLDP VTGRIYNLKS DPPSPEVADR LQIRSDDTKE KHERRMQIYN SQKATLIAHY SDIIIEINAD PEIKVVFKEL QKKINKRLQG TTTQVPLAKL

NT Sequence
atgccactgt ttatcattct atttggcccc cctggcagcg gcaaggggac agtgagccat ctgctcgtaa aagagtacgg ctttgtccac ttgagtgccg gtaatctgct acgcgaagaa gtgctcaaaa agtctccgct agggcggagg tgtgcagaaa tcatgtccga agggtccctg atcccggacg agctcgtcgt cgacctcgtg tgcaaccggc tgagtgagca ggctgtgcag aagcacggta ttttgcttga cggctttcca cggaacctgc ggcaggcaga ggtgctcacg gcgcgcggct tcaagtttga catgatgatt tttctcgacg tgtcgccgga gattttgctc gaccgatgcc tttcccgtcg cctcgacccg gtgacggggc gcatttacaa cctcaagagc gacccgcctt cgccggaggt tgcggaccgt cttcagatcc gctccgacga cacgaaagag aagcacgagc gtcgcatgca gatctacaac agtcagaagg caactctcat cgcccattac tctgacatca tcattgagat caacgcggac ccggagatca aggtagtctt caaggagctg caaaagaaaa tcaacaagcg gttgcagggc accaccacgc aggtccctct ggcaaagctg tag

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