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Seattle Structural Genomics Center for Infectious Disease

LemaA.01610.a: 6-phosphogluconate dehydrogenase, decarboxylating

Target Characteristics

from organism: Leishmania major Friedlin
most recent status: selected
center reference id: LemaA.01610.a
is community request: True
associated disease: Cutaneous leishmaniasis
NIH risk group: 2
is select agent: False
NIH priority
pathogens category:
unclassified

Ordering Clones & Proteins

If there are materials available for this target, they will be listed below. Materials can be ordered from SSGCID using the button in the "order material" column. Clicking the button will add the material to a virtual cart. You may order multiple materials at a time at no cost to you, as this contract is funded by NIAID. When you are ready to place your order, click the "Place Order" link which will appear in the top right corner of the page after you place your first item in your cart.

External Resources

Resource Reference ID
EuPathDB: TritrypDB:LmjF35.3340
OrthoMCL: OG5_127175
RefSeq: XP_843439.1
UniProt: Q9NGR0

Enzyme & Pathway Information

Pathway Pathway ID EC Number
pentose phosphate pathway (oxidative branch) I OXIDATIVEPENT-PWY 1.1.1.44
pentose phosphate pathway (oxidative branch) II OXIDATIVEPENT-PWY-1 1.1.1.44
pentose phosphate pathway PENTOSE-P-PWY 1.1.1.44
superpathway of glucose and xylose degradation PWY-6901 1.1.1.44

Sequences

These sequences are the native gene sequence; sequences of constructs derived from these sequences may differ due to codon optimization or other protocols. To find the specific sequence of any material you may have ordered, click on the "more" button next to the name of that material.
AA Sequence
MSNDLGIIGL GVMGANLALN IAEKGFKVAV FNRTYAKTTS FLKEHESEKF AANLNGYETM KEFAASLKKP RRAFILVQAG AATDSTIEQL KEVFENGDII IDTGNANFKD QDKRAAQLES QGLRFLGMGI SGGEEGARKG PAFFPGGTPS VWEEVRPIVE AAAAKAEDGR PCVTFNGKGG AGSCVKMYHN AGEYAVLQIW GEAYSALLAF GFDNDQIADV FESWKADGFL KSYMLDISIA ACRAREATGN YLSEKVKDRI GSKGTGLWSA QEALEIGVPA PSLNMAVISR QMTMYKGERI ANCKAFPNFP RGPSEEATDK SPNSPEAKKL YHAVSLCIIA SYAQMFQCLR ELDKVYGFGL NLPATIATFR AGCILQGYLL GPMTKAFEEN PNLPNLMDAF TKEIAAGLDD CRQILAKLTV NTAVSLPVMM ASLSYINAMY TETLPYGQLV SLQRDVFGRH GYERTDKDGR ESFEWPALQ

NT Sequence
atgtcgaacg acctcggcat tatcggtctc ggcgtcatgg gcgcgaatct cgccctgaac atcgccgaga agggatttaa agttgccgtc ttcaaccgca cctacgcgaa gacgacgtcg tttctcaagg agcatgagag cgagaaattt gccgccaacc tgaatggata cgagaccatg aaggagttcg ctgcgtccct caagaagccg cgccgcgcgt tcattctcgt ccaggccggc gccgctactg actctacaat cgagcagctc aaggaagtgt tcgagaacgg cgacatcata atcgacactg gtaatgcgaa cttcaaggac caggacaagc gcgcggctca gttggagagc cagggtctcc gcttcctcgg catgggcatc tctggtggtg aggagggtgc gcgcaagggg ccggccttct tcccgggtgg cacaccaagc gtgtgggagg aggtgcgccc gattgtggag gcggctgcgg ccaaggctga ggacggacgc ccgtgcgtga ctttcaacgg caagggcggc gctggctcct gcgtgaagat gtatcacaac gctggggagt acgccgtgct gcagatctgg ggtgaggcgt acagcgccct gcttgccttc ggcttcgaca acgatcagat cgccgacgtg ttcgagtcgt ggaaggcgga tggcttcctt aaatcctaca tgctcgacat ctccattgcc gcttgccgag cgagggaggc aacaggcaac tatttgtcag agaaggtcaa ggaccgcatc ggctccaagg gcaccggcct ctggtctgcc caggaggctc tggagattgg tgtgccagcg ccctcgctca acatggccgt catctcacgc cagatgacca tgtacaaagg ggagcgcatc gccaactgca aggcgtttcc taacttccct cgtggccctt ctgaggaagc cacggacaag tccccgaact cccccgaagc gaagaagctg taccacgccg tcagcctttg tatcatcgcg agctacgcgc agatgttcca gtgcttgcgc gagctggaca aggtgtatgg attcggcctg aacctgcccg ccacgatcgc caccttccgc gccggctgca ttctgcaggg ctacctgcta gggcctatga ccaaggcctt cgaggagaac ccgaacctgc ccaacctgat ggacgccttc accaaggaga tagcggcggg ccttgatgac tgccgtcaga ttctcgccaa gctcacagtg aacacggcag tgtcactgcc ggtcatgatg gcctcactgt cctacatcaa cgccatgtac acggagactc ttccgtacgg acagctggtg tcgttgcagc gcgacgtctt tggccgccac ggctacgagc gcacggacaa ggacggtcgt gagtcgttcg aatggcccgc actgcagtag

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