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Seattle Structural Genomics Center for Infectious Disease

LepnA.00002.a: 2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase

Target Characteristics

from organism: Legionella pneumophila Philadelphia 1 / ATCC 33152 / DSM 7513
most recent status: in PDB
center reference id: LepnA.00002.a
is community request: False
associated disease:
NIH risk group:
is select agent: False
NIH priority
pathogens category:

Ordering Clones & Proteins

If there are materials available for this target, they will be listed below. Materials can be ordered from SSGCID using the button in the "order material" column. Clicking the button will add the material to a virtual cart. You may order multiple materials at a time at no cost to you, as this contract is funded by NIAID. When you are ready to place your order, click the "Place Order" link which will appear in the top right corner of the page after you place your first item in your cart.

Clones*

CENTER
REFERENCE ID
DOMAIN/REGION
DESCRIPTION
INFO AA
START
AA
STOP
ORDER
MATERIAL
LepnA.00002.a.B1.GE41286 Full length(LepnA.00002.a) 1 276 GE41286
* SSGCID clones represent un-induced expression constructs which have been verified by sequencing from vector primers. Clones may contain a tag, such as N-term 6xHis. Get sequence information using the button in the "info" column.

Proteins

CENTER
REFERENCE ID
DOMAIN/REGION
DESCRIPTION
INFO AA
START
AA
STOP
ORDER
MATERIAL
LepnA.00002.a.B1.PS38381 Full length(LepnA.00002.a) 1 276

Structures

image of structure for 6CKT
6CKT
Deposited: 2/28/2018
Determination: XRay
Diffraction Image
Clone: LepnA.00002.a.B1.GE41286
Protein: LepnA.00002.a.B1.PS38381

External Resources

Resource Reference ID
PATRIC ID: fig|272624.6.peg.919
UniProt: Q5ZX45

Enzyme & Pathway Information

Pathway Pathway ID EC Number
L-lysine biosynthesis I DAPLYSINESYN-PWY 2.3.1.117
superpathway of L-lysine, L-threonine and L-methionine biosynthesis I P4-PWY 2.3.1.117
aspartate superpathway PWY0-781 2.3.1.117

Sequences

These sequences are the native gene sequence; sequences of constructs derived from these sequences may differ due to codon optimization or other protocols. To find the specific sequence of any material you may have ordered, click on the "more" button next to the name of that material.
AA Sequence
MNSLQDLIEQ AFENRQNLSL DTASSDLINA INEVLSGLDN GQFRVAEKIN GEWTVHQWLK KAVLLSFKLF PNQIIDAGFC KFYDKIPLKY TDCSNEQFQQ SGVRVVPHAM VRRGAYIAKN TVLMPSYVNI GAYIDEGVMV DTWATVGSCA QIGKNVHISG GAGIGGVLEP LQANPTIIED NCFIGARSEI VEGVIVEKNS VISMGVFLGQ STKIYNRITG EVSYGRIPAG SVVVAGNLPS HDGSHSLYCA VIVKQVDEKT RAKVSINDLL RANQDD

NT Sequence
ATGAACTCAC TTCAAGATCT AATTGAACAA GCCTTTGAAA ACCGTCAAAA TTTATCGCTC GACACAGCCT CCTCAGATTT GATCAATGCC ATTAATGAAG TTCTCAGTGG TCTGGATAAT GGCCAATTCA GAGTCGCTGA AAAAATAAAT GGTGAATGGA CAGTTCATCA ATGGCTTAAA AAGGCAGTTC TTTTATCCTT TAAACTTTTC CCAAATCAAA TCATAGACGC GGGTTTTTGC AAGTTTTACG ATAAAATACC GCTAAAATAT ACGGATTGTA GTAATGAGCA ATTTCAACAA TCAGGGGTAA GAGTTGTTCC TCATGCCATG GTACGACGTG GAGCATATAT TGCCAAAAAT ACTGTTTTAA TGCCTTCTTA TGTCAATATA GGTGCTTATA TTGATGAGGG AGTAATGGTT GATACCTGGG CAACTGTTGG TTCTTGTGCC CAAATAGGAA AAAATGTACA TATATCTGGC GGCGCAGGTA TAGGAGGTGT TTTAGAACCA TTACAAGCGA ACCCAACCAT CATTGAGGAC AATTGCTTTA TTGGTGCCCG CTCTGAAATA GTGGAAGGGG TTATCGTAGA AAAAAACTCC GTCATATCAA TGGGAGTATT TTTAGGCCAA AGCACTAAAA TCTACAATCG AATCACTGGC GAAGTAAGCT ACGGCAGAAT TCCGGCTGGC TCAGTAGTTG TTGCAGGTAA TTTGCCAAGT CATGATGGAA GCCACAGTCT ATATTGTGCT GTCATTGTGA AACAAGTGGA TGAAAAAACT CGCGCGAAGG TAAGCATTAA TGATTTACTA AGAGCCAATC AAGATGAC

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