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Seattle Structural Genomics Center for Infectious Disease

LepnA.00102.a: 2-dehydro-3-deoxyphosphooctonate aldolase

Target Characteristics

from organism: Legionella pneumophila Philadelphia 1 / ATCC 33152 / DSM 7513
most recent status: in PDB
center reference id: LepnA.00102.a
is community request: False
associated disease:
NIH risk group:
is select agent: False
NIH priority
pathogens category:

Ordering Clones & Proteins

If there are materials available for this target, they will be listed below. Materials can be ordered from SSGCID using the button in the "order material" column. Clicking the button will add the material to a virtual cart. You may order multiple materials at a time at no cost to you, as this contract is funded by NIAID. When you are ready to place your order, click the "Place Order" link which will appear in the top right corner of the page after you place your first item in your cart.

Clones*

CENTER
REFERENCE ID
DOMAIN/REGION
DESCRIPTION
INFO AA
START
AA
STOP
ORDER
MATERIAL
LepnA.00102.a.B1.GE41353 Full length(LepnA.00102.a) 1 274 GE41353
* SSGCID clones represent un-induced expression constructs which have been verified by sequencing from vector primers. Clones may contain a tag, such as N-term 6xHis. Get sequence information using the button in the "info" column.

Proteins

CENTER
REFERENCE ID
DOMAIN/REGION
DESCRIPTION
INFO AA
START
AA
STOP
ORDER
MATERIAL
LepnA.00102.a.B1.PS38404 Full length(LepnA.00102.a) 1 274

Structures

image of structure for 6MDY
6MDY
Deposited: 9/5/2018
Determination: XRay
Diffraction Image
Clone: LepnA.00102.a.B1.GE41353
Protein: LepnA.00102.a.B1.PS38404

External Resources

Resource Reference ID
PATRIC ID: fig|272624.6.peg.1245
UniProt: Q5ZWA3

Enzyme & Pathway Information

Pathway Pathway ID EC Number
superpathway of (KDO)2-lipid A biosynthesis KDO-NAGLIPASYN-PWY 2.5.1.55
superpathway of lipopolysaccharide biosynthesis LPSSYN-PWY 2.5.1.55
CMP-3-deoxy-D-manno-octulosonate biosynthesis PWY-1269 2.5.1.55
CMP-3-deoxy-D-manno-octulosonate biosynthesis II (from D-arabinose 5-phosphate) PWY-5111 2.5.1.55
CMP-8-amino-3,8-dideoxy-D-manno-octulosonate biosynthesis PWY-7674 2.5.1.55

Sequences

These sequences are the native gene sequence; sequences of constructs derived from these sequences may differ due to codon optimization or other protocols. To find the specific sequence of any material you may have ordered, click on the "more" button next to the name of that material.
AA Sequence
MRLCGFEAGL DKPLFLIAGP CVIESEELAL ETAGYLKEMC SQLNIPFIYK SSFDKANRSS ISSYRGPGFE KGLSILEKVK SQIGVPVLTD VHEDTPLFEV SSVVDVLQTP AFLCRQTNFI QKVAAMNKPV NIKKGQFLAP WEMKHVIAKA KAQGNEQIMA CERGVSFGYN NLVSDMRSLV IMRETGCPVV YDATHSVQLP GGNNGVSGGQ REFIPALARA AVAVGISGLF METHPDPDKA LSDGPNSWPL DKMKQLLESL KAADEVYKKY STDF

NT Sequence
ATGAGATTAT GTGGTTTTGA AGCAGGCTTG GATAAGCCAT TGTTTTTGAT TGCCGGCCCT TGTGTTATTG AAAGTGAAGA ATTGGCTTTA GAGACCGCAG GATATTTAAA GGAAATGTGC AGTCAGTTGA ATATCCCTTT CATCTATAAG TCTTCTTTTG ATAAAGCAAA CCGTTCATCT ATTTCCAGTT ACAGGGGGCC TGGCTTTGAA AAAGGGTTAT CGATTCTGGA AAAGGTTAAA TCACAAATAG GTGTTCCTGT TTTGACTGAT GTTCATGAAG ACACGCCCTT ATTTGAAGTC TCCAGTGTGG TAGATGTATT ACAAACGCCA GCCTTCCTAT GCAGACAAAC CAATTTTATC CAAAAAGTTG CTGCCATGAA TAAGCCGGTT AATATTAAAA AAGGACAGTT TCTTGCTCCC TGGGAAATGA AACATGTTAT TGCGAAGGCA AAGGCGCAAG GTAATGAGCA AATTATGGCT TGTGAGCGAG GAGTGAGCTT CGGCTACAAT AATTTGGTTT CTGATATGCG TTCCCTCGTT ATCATGCGTG AAACCGGCTG TCCAGTGGTT TATGATGCAA CACATTCGGT TCAATTGCCC GGGGGCAATA ATGGTGTATC CGGGGGGCAG AGAGAATTTA TTCCGGCTCT TGCAAGAGCA GCTGTAGCTG TTGGAATATC AGGGTTATTT ATGGAAACTC ACCCTGATCC GGATAAGGCA CTAAGTGATG GTCCCAATAG TTGGCCTCTA GATAAAATGA AACAACTTTT GGAATCATTG AAAGCAGCGG ATGAAGTATA TAAAAAGTAC AGTACTGATT TC

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