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Seattle Structural Genomics Center for Infectious Disease

LepnA.01212.a: Malate dehydrogenase

Target Characteristics

from organism: Legionella pneumophila Philadelphia 1 / ATCC 33152 / DSM 7513
most recent status: in PDB
center reference id: LepnA.01212.a
is community request: False
associated disease:
NIH risk group:
is select agent: False
NIH priority
pathogens category:

Ordering Clones & Proteins

If there are materials available for this target, they will be listed below. Materials can be ordered from SSGCID using the button in the "order material" column. Clicking the button will add the material to a virtual cart. You may order multiple materials at a time at no cost to you, as this contract is funded by NIAID. When you are ready to place your order, click the "Place Order" link which will appear in the top right corner of the page after you place your first item in your cart.

Clones*

CENTER
REFERENCE ID
DOMAIN/REGION
DESCRIPTION
INFO AA
START
AA
STOP
ORDER
MATERIAL
LepnA.01212.a.B1.GE41627 Full length(LepnA.01212.a) 1 330 GE41627
* SSGCID clones represent un-induced expression constructs which have been verified by sequencing from vector primers. Clones may contain a tag, such as N-term 6xHis. Get sequence information using the button in the "info" column.

Proteins

CENTER
REFERENCE ID
DOMAIN/REGION
DESCRIPTION
INFO AA
START
AA
STOP
ORDER
MATERIAL
LepnA.01212.a.B1.PS38424 Full length(LepnA.01212.a) 1 330

Structures

image of structure for 6PBL
6PBL
Deposited: 6/14/2019
Determination: XRay
Diffraction Image
Clone: LepnA.01212.a.B1.GE41627
Protein: LepnA.01212.a.B1.PS38424

External Resources

Resource Reference ID
PATRIC ID: fig|272624.6.peg.2473
UniProt: Q5ZT13

Enzyme & Pathway Information

Pathway Pathway ID EC Number
respiration (anaerobic) ANARESP1-PWY 1.1.1.37
mixed acid fermentation FERMENTATION-PWY 1.1.1.37
gluconeogenesis I GLUCONEO-PWY 1.1.1.37
superpathway of glycolysis, pyruvate dehydrogenase, TCA, and glyoxylate bypass GLYCOLYSIS-TCA-GLYOX-BYPASS 1.1.1.37
glyoxylate cycle GLYOXYLATE-BYPASS 1.1.1.37
L-aspartate degradation II MALATE-ASPARTATE-SHUTTLE-PWY 1.1.1.37
TCA cycle IV (2-oxoglutarate decarboxylase) P105-PWY 1.1.1.37
pyruvate fermentation to propanoate I P108-PWY 1.1.1.37
reductive TCA cycle I P23-PWY 1.1.1.37
incomplete reductive TCA cycle P42-PWY 1.1.1.37
formaldehyde assimilation I (serine pathway) PWY-1622 1.1.1.37
L-carnitine degradation III PWY-3641 1.1.1.37
L-glutamate degradation VIII (to propanoate) PWY-5088 1.1.1.37
reductive TCA cycle II PWY-5392 1.1.1.37
superpathway of cytosolic glycolysis (plants), pyruvate dehydrogenase and TCA cycle PWY-5464 1.1.1.37
superpathway of glyoxylate cycle and fatty acid degradation PWY-561 1.1.1.37
TCA cycle II (plants and fungi) PWY-5690 1.1.1.37
partial TCA cycle (obligate autotrophs) PWY-5913 1.1.1.37
Methanobacterium thermoautotrophicum biosynthetic metabolism PWY-6146 1.1.1.37
TCA cycle III (animals) PWY66-398 1.1.1.37
gluconeogenesis III PWY66-399 1.1.1.37
methylaspartate cycle PWY-6728 1.1.1.37
TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase) PWY-6969 1.1.1.37
malate-oxaloacetate shuttle I PWY-7047 1.1.1.37
malate-oxaloacetate shuttle II PWY-7048 1.1.1.37
C4 photosynthetic carbon assimilation cycle, NAD-ME type PWY-7115 1.1.1.37
chitin degradation to ethanol PWY-7118 1.1.1.37
anaerobic energy metabolism (invertebrates, cytosol) PWY-7383 1.1.1.37
anaerobic energy metabolism (invertebrates, mitochondrial) PWY-7384 1.1.1.37
superpathway of anaerobic energy metabolism (invertebrates) PWY-7389 1.1.1.37
TCA cycle I (prokaryotic) TCA 1.1.1.37
superpathway of glyoxylate bypass and TCA TCA-GLYOX-BYPASS 1.1.1.37

Sequences

These sequences are the native gene sequence; sequences of constructs derived from these sequences may differ due to codon optimization or other protocols. To find the specific sequence of any material you may have ordered, click on the "more" button next to the name of that material.
AA Sequence
MTNNRVRVAV TGAAGQIGYA LVFRIASGQM FGPNTEVELN LLELEPALPS LEGVAMELDD CAFPLLKRIV CTADLNKAMD GVNWALLVGS VPRKQGMERS DLLQINGGIF TKQGQAINDY ASDDVRVFVV GNPCNTNCLI AMNHAKDVPS DRFYAMTTLD ELRARTQLAK KAGVDITAVT QMTIWGNHSA TQYPDFYNAK INGTSAAQVI NDETWLKETF VSTVQQRGAA VIKARGSSSA ASAANAIITG VNHLVTDTPA GESFSMCRRS KGEYGVDEGL IFSFPCRREH GELKVVENLE FNDFGRERFN TTLNELRSER DTVKSLGLLD

NT Sequence
ATGACAAATA ATCGAGTAAG AGTTGCTGTC ACAGGTGCAG CAGGGCAAAT AGGTTATGCC TTGGTGTTTC GTATTGCTTC CGGTCAAATG TTTGGGCCAA ATACTGAAGT GGAATTGAAT TTACTTGAAC TTGAGCCGGC ACTTCCCTCA CTGGAAGGAG TCGCTATGGA GCTTGATGAT TGCGCATTTC CCTTATTAAA ACGCATTGTT TGTACTGCAG ATTTGAATAA GGCAATGGAT GGTGTTAACT GGGCATTATT AGTCGGTTCA GTTCCGCGAA AGCAAGGCAT GGAGCGTTCT GATTTATTAC AAATCAATGG TGGTATATTC ACCAAACAAG GTCAGGCGAT TAATGATTAT GCCAGTGATG ATGTACGGGT ATTTGTTGTG GGAAACCCTT GCAATACCAA TTGCCTAATT GCTATGAATC ACGCAAAAGA CGTGCCTTCT GATCGTTTTT ATGCAATGAC CACATTGGAT GAGTTAAGAG CTCGTACTCA ATTGGCTAAA AAAGCAGGCG TTGACATTAC TGCAGTGACT CAAATGACGA TTTGGGGTAA TCATTCCGCC ACCCAATATC CCGATTTTTA TAACGCAAAA ATCAATGGAA CTTCTGCTGC GCAAGTCATT AATGATGAAA CCTGGTTAAA AGAGACTTTT GTATCAACCG TCCAGCAACG AGGAGCCGCA GTGATCAAGG CACGGGGTTC ATCTTCTGCT GCTTCTGCCG CCAATGCGAT AATTACAGGA GTTAATCATT TGGTTACGGA TACTCCTGCT GGCGAATCGT TTTCAATGTG CCGTCGCTCA AAGGGAGAGT ACGGAGTCGA TGAAGGTTTG ATTTTCTCTT TCCCATGCCG AAGAGAACAT GGCGAATTAA AAGTGGTCGA GAACTTGGAG TTCAACGATT TTGGCCGCGA GAGATTCAAT ACCACTTTAA ACGAATTACG AAGTGAGCGT GACACGGTCA AGTCTTTAGG CTTATTGGAT

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