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Seattle Structural Genomics Center for Infectious Disease

MyabA.01156.a: Probable o-acetylhomoserine sulfhydrylase MetC (Homocysteine synthase)

Target Characteristics

from organism: Mycobacterium abscessus ATCC 19977 / DSM 44196
most recent status: diffraction
center reference id: MyabA.01156.a
is community request: False
associated disease: Skin abscess
NIH risk group: 2
is select agent: False
NIH priority
pathogens category:
IIIC

Ordering Clones & Proteins

If there are materials available for this target, they will be listed below. Materials can be ordered from SSGCID using the button in the "order material" column. Clicking the button will add the material to a virtual cart. You may order multiple materials at a time at no cost to you, as this contract is funded by NIAID. When you are ready to place your order, click the "Place Order" link which will appear in the top right corner of the page after you place your first item in your cart.

Clones*

CENTER
REFERENCE ID
DOMAIN/REGION
DESCRIPTION
INFO AA
START
AA
STOP
ORDER
MATERIAL
MyabA.01156.a.A1.GE30482 Full length( MyabA.01156.a ) 1 453 GE30482
* SSGCID clones represent un-induced expression constructs which have been verified by sequencing from vector primers. Clones may contain a tag, such as N-term 6xHis. Get sequence information using the button in the "info" column.

Proteins

CENTER
REFERENCE ID
DOMAIN/REGION
DESCRIPTION
INFO AA
START
AA
STOP
ORDER
MATERIAL
MyabA.01156.a.A1.PS00911 Full length( MyabA.01156.a ) 1 453

External Resources

Resource Reference ID
OrthoMCL: OG5_130839
PATRIC ID: fig|36809.5.peg.3755
RefSeq: YP_001704415.1
UniProt: B1MG16

Enzyme & Pathway Information

Pathway Pathway ID EC Number
L-methionine biosynthesis III HSERMETANA-PWY 2.5.1.49
L-homocysteine biosynthesis PWY-5344 2.5.1.49
superpathway of L-methionine biosynthesis (by sulfhydrylation) PWY-5345 2.5.1.49
superpathway of L-cysteine biosynthesis (fungi) PWY-6293 2.5.1.49
S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation II PWY-7174 2.5.1.49
superpathway of sulfur amino acid biosynthesis (Saccharomyces cerevisiae) PWY-821 2.5.1.49

Sequences

These sequences are the native gene sequence; sequences of constructs derived from these sequences may differ due to codon optimization or other protocols. To find the specific sequence of any material you may have ordered, click on the "more" button next to the name of that material.
AA Sequence
MTDIDPTTAD SRSDKPRSAQ WAFETKQIHA GQSADAATNA RALPIYQTTS YVFNDTAHAA ALFGLSEEGN IYTRIGNPTQ DVVEQRIAAL EGGVAALLLA SGQAAATLAI VNIAQAGDNI VSSPRLYGGT YNLLHYTLPR LGISTTFVED PDDLESWRNA ITPDTKALFA ESISNPQNDI LDIAGLSEIA HAAGIPLIVD NTVATPYLIQ PLAHGADVVV HSATKYLGGH GNAIGGVIID GGTFDWTQGR HPGFTTPDPS YHGVVFADLG APAYALKARV QLLRDLGPAI SPFNAFLIAQ GLETLSLRVE RHVANAQRVA EFLVAQPEVT RVNYAGLPTS PWYERAKALA PKGAGAVLAF ELDGGVEAAT TFIDSLTLHS QVANIGDVRS LVIHPATTTH GQLSPAEQVA SGVTPGLVRL AVGIEGIDDI LADLESGFTA VRRLKQPAAV ASS

NT Sequence
ATGACCGATA TCGATCCCAC CACAGCAGAC AGTCGCTCGG ACAAGCCTCG CTCCGCCCAG TGGGCGTTCG AGACCAAGCA GATCCACGCG GGCCAGTCCG CCGACGCGGC AACCAACGCG CGGGCCCTGC CGATCTACCA GACCACCTCC TACGTCTTCA ACGACACCGC GCACGCCGCG GCGCTCTTCG GGCTGTCCGA AGAGGGCAAC ATCTACACCC GCATCGGCAA CCCCACCCAG GATGTCGTCG AGCAGCGCAT CGCAGCCCTG GAAGGTGGCG TGGCCGCGCT GCTACTTGCC TCCGGACAGG CGGCGGCGAC CCTGGCGATC GTGAACATCG CACAGGCCGG CGACAACATC GTCTCCAGCC CGCGCCTGTA CGGAGGCACC TACAATCTGC TGCACTACAC GCTGCCACGA CTGGGCATCT CGACTACCTT CGTCGAAGAC CCCGACGATC TGGAGTCGTG GCGCAACGCC ATCACCCCGG ATACCAAGGC GCTGTTCGCC GAGTCGATCT CCAACCCGCA GAACGACATT CTCGACATCG CCGGCCTGTC GGAGATCGCG CACGCGGCAG GCATCCCGCT GATCGTCGAC AACACCGTCG CCACCCCCTA TCTGATCCAG CCGCTGGCAC ACGGGGCCGA CGTCGTGGTG CATTCGGCCA CCAAATACCT TGGTGGACAC GGCAATGCAA TCGGCGGCGT GATCATCGAC GGAGGTACCT TCGACTGGAC CCAGGGTCGC CATCCCGGAT TCACCACCCC CGACCCGAGT TACCACGGCG TGGTGTTCGC CGATCTGGGC GCGCCGGCCT ACGCACTTAA GGCGCGTGTG CAGCTGCTGC GCGACCTCGG TCCCGCCATC TCGCCATTCA ACGCATTCCT CATCGCTCAG GGTTTGGAAA CATTGAGCCT GCGCGTGGAG CGGCACGTGG CGAACGCACA GCGGGTGGCC GAATTCCTTG TCGCACAGCC GGAAGTCACT CGCGTCAACT ACGCCGGGCT ACCCACATCT CCATGGTACG AGCGCGCGAA GGCCTTGGCC CCCAAGGGAG CCGGTGCCGT GCTCGCATTC GAACTGGACG GTGGTGTCGA GGCTGCGACC ACCTTCATCG ATTCCCTGAC CCTGCACAGC CAGGTCGCCA ACATCGGTGA TGTGCGTTCG CTTGTCATCC ACCCGGCCAC CACAACGCAC GGACAGCTCT CCCCTGCCGA ACAGGTGGCC TCCGGGGTCA CGCCGGGACT GGTCCGGTTG GCCGTCGGCA TCGAGGGCAT CGACGACATC CTGGCCGACC TGGAGTCCGG ATTCACGGCC GTACGCAGGC TCAAACAACC CGCGGCGGTG GCATCATCG

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