NIAID Emerging and Re-emerging Infectious Diseases NIAID Bioinformatics Resource Centers NIAID Structural Genomic Centers Center for Structural Genomics of Infectious Disease
Seattle Structural Genomics Center for Infectious Disease

MyabA.01570.a: 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase (FolK) (Rv3606c ortholog)

Target Characteristics

from organism: Mycobacterium abscessus ATCC 19977 / DSM 44196
most recent status: purified
center reference id: MyabA.01570.a
is community request: True
associated disease: Skin abscess
NIH risk group: 2
is select agent: False
NIH priority
pathogens category:
IIIC

Ordering Clones & Proteins

If there are materials available for this target, they will be listed below. Materials can be ordered from SSGCID using the button in the "order material" column. Clicking the button will add the material to a virtual cart. You may order multiple materials at a time at no cost to you, as this contract is funded by NIAID. When you are ready to place your order, click the "Place Order" link which will appear in the top right corner of the page after you place your first item in your cart.

Clones*

CENTER
REFERENCE ID
DOMAIN/REGION
DESCRIPTION
INFO AA
START
AA
STOP
ORDER
MATERIAL
MyabA.01570.a.B1.GE37300 full length 1 172 GE37300
* SSGCID clones represent un-induced expression constructs which have been verified by sequencing from vector primers. Clones may contain a tag, such as N-term 6xHis. Get sequence information using the button in the "info" column.

Proteins

CENTER
REFERENCE ID
DOMAIN/REGION
DESCRIPTION
INFO AA
START
AA
STOP
ORDER
MATERIAL
MyabA.01570.a.B1.PS01940 full length 1 172

External Resources

Resource Reference ID
PATRIC ID: fig|36809.5.peg.577
RefSeq: YP_001701290.1
UniProt: B1MGV2

Enzyme & Pathway Information

Pathway Pathway ID EC Number
superpathway of chorismate metabolism ALL-CHORISMATE-PWY 2.7.6.3
superpathway of tetrahydrofolate biosynthesis and salvage FOLSYN-PWY 2.7.6.3
6-hydroxymethyl-dihydropterin diphosphate biosynthesis I PWY-6147 2.7.6.3
tetrahydromethanopterin biosynthesis PWY-6148 2.7.6.3
superpathway of tetrahydrofolate biosynthesis PWY-6612 2.7.6.3
6-hydroxymethyl-dihydropterin diphosphate biosynthesis II (Methanocaldococcus) PWY-6797 2.7.6.3
6-hydroxymethyl-dihydropterin diphosphate biosynthesis III (Chlamydia) PWY-7539 2.7.6.3
6-hydroxymethyl-dihydropterin diphosphate biosynthesis IV (Plasmodium) PWY-7852 2.7.6.3
6-hydroxymethyl-dihydropterin diphosphate biosynthesis V (Pyrococcus) PWY-7853 2.7.6.3

Sequences

These sequences are the native gene sequence; sequences of constructs derived from these sequences may differ due to codon optimization or other protocols. To find the specific sequence of any material you may have ordered, click on the "more" button next to the name of that material.
AA Sequence
MRAVLSIGSN VGDRLAHLQS VVDALGSDVV GVSPVYQTAP WGHVPQPDFF NAIVVADGRE PLEWLAVAHR LEQSAQRLRD ERWGPRTLDV DVISCRRHDA GEVLSDDPDL TLPHPRAHLR AFVLVPWLAL EPGAVLTVDG VVRPVADLLS GLDAAEREGV RRMDAALTGP VT

NT Sequence
gtgcgtgccg tgctttcgat cggctccaat gtcggtgaca ggctcgcgca cctgcaatcg gtggtggacg cactgggctc ggacgtggtc ggcgtctcgc cggtgtatca gaccgctccg tgggggcatg ttccgcagcc ggacttcttc aacgcaatcg tcgtcgccga cggacgcgag cccctggagt ggcttgcggt ggcgcaccgc ctggagcagt cggcgcagcg attgcgcgac gagcgttggg gtccaaggac tctcgacgtt gatgtgatca gctgtcgtcg ccatgatgct ggtgaggtcc tttccgatga cccggatctc acgctgccgc atccgcgtgc gcatctgcgg gccttcgtgc tggtgccgtg gctggcgctg gagcccggcg cggtactcac cgtcgacggt gtggtgcgcc cggtggccga cctgctgtcc ggactcgacg cggccgaacg cgagggtgtg cggcggatgg atgccgccct gaccggtccg gtgacgtag

© 2020 Seattle Children's Research Institute. All rights reserved.