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Seattle Structural Genomics Center for Infectious Disease

MyavA.00170.a: Enoyl-[acyl-carrier-protein] reductase [NADH] (EC 1.3.1.9) (InhA)

Target Characteristics

from organism: Mycobacterium avium 104
most recent status: in PDB
center reference id: MyavA.00170.a
is community request: True
associated disease: Johne's disease, paratuberculosis
NIH risk group: 2
is select agent: False
NIH priority
pathogens category:
IIIC

Ordering Clones & Proteins

If there are materials available for this target, they will be listed below. Materials can be ordered from SSGCID using the button in the "order material" column. Clicking the button will add the material to a virtual cart. You may order multiple materials at a time at no cost to you, as this contract is funded by NIAID. When you are ready to place your order, click the "Place Order" link which will appear in the top right corner of the page after you place your first item in your cart.

Clones*

CENTER
REFERENCE ID
DOMAIN/REGION
DESCRIPTION
INFO AA
START
AA
STOP
ORDER
MATERIAL
MyavA.00170.a.B1.GE42831 full length 1 269 GE42831
* SSGCID clones represent un-induced expression constructs which have been verified by sequencing from vector primers. Clones may contain a tag, such as N-term 6xHis. Get sequence information using the button in the "info" column.

Proteins

CENTER
REFERENCE ID
DOMAIN/REGION
DESCRIPTION
INFO AA
START
AA
STOP
ORDER
MATERIAL
MyavA.00170.a.B1.PS38585 full length 1 269

Structures

image of structure for 6Q1Y
6Q1Y
Deposited: 8/6/2019
Determination: XRay
Diffraction Image
Clone: MyavA.00170.a.B1.GE42831
Protein: MyavA.00170.a.B1.PS38585

External Resources

Resource Reference ID
UniProt: A0A0H2ZSV5

Enzyme & Pathway Information

Pathway Pathway ID EC Number
biotin biosynthesis I BIOTIN-BIOSYNTHESIS-PWY 1.3.1.9
fatty acid elongation -- saturated FASYN-ELONG-PWY 1.3.1.9
(5Z)-dodecenoate biosynthesis I PWY0-862 1.3.1.9
superpathway of fatty acid biosynthesis I (E. coli) PWY0-881 1.3.1.9
superpathway of fatty acid biosynthesis II (plant) PWY-5156 1.3.1.9
palmitate biosynthesis II (bacteria and plants) PWY-5971 1.3.1.9
cis-vaccenate biosynthesis PWY-5973 1.3.1.9
stearate biosynthesis II (bacteria and plants) PWY-5989 1.3.1.9
superpathway of mycolate biosynthesis PWY-6113 1.3.1.9
palmitoleate biosynthesis I (from (5Z)-dodec-5-enoate) PWY-6282 1.3.1.9
superpathway of unsaturated fatty acids biosynthesis (E. coli) PWY-6284 1.3.1.9
superpathway of fatty acids biosynthesis (E. coli) PWY-6285 1.3.1.9
8-amino-7-oxononanoate biosynthesis I PWY-6519 1.3.1.9
triclosan resistance PWY-7096 1.3.1.9
gondoate biosynthesis (anaerobic) PWY-7663 1.3.1.9
oleate biosynthesis IV (anaerobic) PWY-7664 1.3.1.9
(5Z)-dodecenoate biosynthesis II PWY-7858 1.3.1.9
mycolate biosynthesis PWYG-321 1.3.1.9

Sequences

These sequences are the native gene sequence; sequences of constructs derived from these sequences may differ due to codon optimization or other protocols. To find the specific sequence of any material you may have ordered, click on the "more" button next to the name of that material.
AA Sequence
MAGLLDGKRI LVTGIITDSS IAFHIAKVAQ EAGAQLVLTG FDRLRLIQRI VDRLPEKAPL IELDVQNEEH LNTLAQRVTA EIGEGNKLDG VVHSIGFMPQ TGMGINPFFD APYEDVSKGI HISAYSYASL AKALLPIMNP GGSIVGMDFD PSRAMPAYNW MTVAKSALES VNRFVAREAG PHGVRSNLVA AGPIRTLAMA GIVGGVLGDQ AAEQIRLLEE GWDQRAPIGW NMKDPTPVAK TVCALLSDWL PATTGTIIYA DGGASTQLL

NT Sequence
atggcaggac tgctcgacgg caaacggatc ctggtcaccg ggatcatcac cgactcgtcg atcgcgtttc acatcgccaa ggtggcccag gaggccgggg cgcagttggt gctgaccggc ttcgaccggc tgcggctgat ccagcgcatc gtcgaccggc tgccggagaa ggccccgttg atcgagctcg acgtgcagaa cgaggagcac ctgaacaccc tggcccagcg ggtgaccgcc gagatcggcg agggcaacaa gctcgacggg gtggtgcact cgatcggctt catgccgcag accggcatgg gcatcaaccc gttcttcgac gcgccgtacg aggatgtctc caaaggcatt cacatctcgg cgtattcgta cgcctcgctg gccaaggcgc tgctgccgat catgaacccc ggcgggtcga tcgtgggcat ggacttcgac cccagccggg cgatgccggc ctacaactgg atgacggtcg cgaagagcgc gctggagtcg gtcaaccggt tcgtggcgcg cgaggccggg ccgcacggcg tgcgctcgaa tctcgttgcg gcgggcccga tccgcacgct ggcgatggcc gggatcgtcg gcggcgtgct cggcgaccag gcggccgagc agatccggct gctggaggag ggctgggatc agcgggcccc gatcggctgg aacatgaagg accccacccc ggtggccaag acggtgtgcg cgctgctgtc cgactggctg ccggccacca ccggcaccat catctacgcc gacggcggcg ccagcaccca attgctgtag

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