MyavA.00640.a: Acetate kinase
Target Characteristics
| from organism: | Mycobacterium avium 104 |
| most recent status: | in PDB |
| center reference id: | MyavA.00640.a |
| is community request: | False |
| associated disease: | Johne's disease, paratuberculosis |
| NIH risk group: | 2 |
| is select agent: | False |
| NIH priority pathogens category: |
IIIC |
Ordering Clones & Proteins
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Clones*
| CENTER REFERENCE ID |
DOMAIN/REGION DESCRIPTION |
INFO | AA START |
AA STOP |
ORDER MATERIAL |
|---|---|---|---|---|---|
| MyavA.00640.a.A1.GE28563 | Full length( MyavA.00640.a ) | 1 | 387 | GE28563 |
* SSGCID clones represent un-induced expression constructs which have been verified by sequencing from vector primers. Clones may contain a tag, such as N-term 6xHis. Get sequence information
using the button in the "info" column.
Structures
3P4I
Deposited: 10/6/2010
Determination: XRay
Diffraction Image
Clone: MyavA.00640.a.A1.GE28563
Protein: MyavA.00640.a.A1.PS00663
4IZ9
Deposited: 1/29/2013
Determination: XRay
Diffraction Image
Clone: MyavA.00640.a.A1.GE28563
Protein: MyavA.00640.a.A1.PS00663
Publications by SSGCID
Increasing the structural coverage of tuberculosis drug targets.
Abendroth J, Abramov A, Armour B, Barrett LK, Baugh L, Begley DW, Buchko GW, Choi R, Clifton MC, Dieterich SH, Dranow DM, Edwards TE, Fairman JW, Ferrell M, Fox D, Gardberg AS, Hewitt SN, Lorimer D, Lyons-Abbott S, Mundt E, Muruthi MM, Myers J, Myler PJ, Napuli AJ, Phan I, Sekar A, Serbzhinskiy D, Stacy R, Staker BL, Stewart LJ, Taylor BM, Thompkins K, Tran N, Van Voorhis WC, Zhang Y
Tuberculosis (Edinb) - 2014
volume 95, issue 2, pages 142-8
PMID: 25613812; PMCID: PMC4361283
PDB:
3GVC,
3GVG,
3GWC,
3H7F,
3H81,
3HE2,
3HWI,
3HWK,
3HZG,
3ICO,
3KHP,
3LLS,
3MOY,
3MPZ,
3MYB,
3NDN,
3NDO,
3NF4,
3NG3,
3NJD,
3NWO,
3O0M,
3O38,
3OC6,
3OC7,
3OEC,
3OI9,
3OKS,
3OL3,
3OL4,
3OME,
3P0T,
3P2Y,
3P4I,
3P4T,
3P5M,
3P85,
3PE8,
3PGX,
3PK0,
3PPI,
3PXX,
3PZY,
3Q1T,
3Q8N,
3QBP,
3QDF,
3QH4,
3QHA,
3QIV,
3QK8,
3QKA,
3QLJ,
3QMJ,
3QRE,
3QUA,
3QUV,
3QXI,
3QXZ,
3QYR,
3R0O,
3R1I,
3R1J,
3R20,
3R2N,
3R4T,
3R6H,
3R6O,
3R7K,
3R8C,
3R9P,
3R9Q,
3R9R,
3R9S,
3R9T,
3RD5,
3RD7,
3RD8,
3RFQ,
3RIH,
3RR2,
3RR6,
3RRP,
3RRV,
3RSI,
3RV2,
3S55,
3S82,
3SBX,
3SF6,
3SLL,
3SVK,
3SVT,
3SWO,
3SWT,
3SWX,
3SX2,
3T3W,
3T7C,
3TAV,
3TCR,
3TDE,
3TJR,
3TL3,
3TLF,
3TRR,
3TSC,
3TX2,
3TZQ,
3TZU,
3U0A,
3U0B,
3UCX,
3UVE,
4DI1,
4DIE,
4DQ8,
4DXL,
4ED4,
4EGE,
4EGF,
4EMD,
4EO9,
4EYE,
4F3W,
4F47,
4FFC,
4GK6,
4HDT,
4HR3,
4I1Y,
4IJN,
4IV6,
4IZ9,
4J5I,
4KAM,
4LGV,
4O2D,
5EJ2
Citations by Others
| Investigation of pyrophosphate versus ATP substrate selection in the Entamoeba histolytica acetate kinase | |
| T Dang, C Ingram-Smith- Scientific Reports, 2017 - ncbi.nlm.nih.gov | |
| PDB: 3P4I |
| Structural and mechanistic investigations on Salmonella typhimurium acetate kinase (AckA): identification of a putative ligand binding pocket at the dimeric interface | |
| S Chittori, H Savithri, M Murthy - BMC structural biology, 2012 - biomedcentral.com | |
| cited by: | 10 others |
| PDB: 3P4I | |
| Significant reduction in errors associated with nonbonded contacts in protein crystal structures: automated all-atom refinement with PrimeX | |
| JA Bell, KL Ho, R Farid - Acta Crystallographica Section D: Biological Crystallography, 2012 - scripts.iucr.org | |
| cited by: | 10 others |
| PDB: 3P4I | |
| Mechanistic features of< i> Salmonella typhimurium propionate kinase (TdcD): Insights from kinetic and crystallographic studies | |
| S Chittori, DK Simanshu, S Banerjee? - Biochimica et Biophysica Acta (BBA) - Proteins and Proteomics, 2013 - Elsevier | |
| cited by: | 2 others |
| PDB: 4IZ9 | |
This list was obtained from Google Scholar searches using the Open Source tool https://github.com/ckreibich/scholar.py and each citation has been manually reviewed.
External Resources
| Resource | Reference ID |
|---|---|
| OrthoMCL: | OG5_130287 |
| PATRIC ID: | fig|243243.7.peg.4678 |
| RefSeq: | YP_883886.1 |
| UniProt: | A0QLU8 |
Enzyme & Pathway Information
| Pathway | Pathway ID | EC Number |
|---|---|---|
| (S)-propane-1,2-diol degradation | PWY-7013 | 2.7.2.1 |
| superpathway of L-threonine metabolism | THREOCAT-PWY | 2.7.2.1 |
Sequences
These sequences are the native gene sequence; sequences of constructs derived from these sequences may differ due to codon optimization or other protocols.
To find the specific sequence of any material you may have ordered, click on the "more" button next to the name of that material.
AA Sequence
MDGSDGARRV LVINSGSSSL KFQLVDPESG VAASTGIVER IGEESSPVPD HDAALRRAFD MLAGDGVDLN TAGLVAVGHR VVHGGNTFYR PTVLDDAVIA RLHELSELAP LHNPPALLGI EVARRLLPGI AHVAVFDTGF FHDLPPAAAT YAIDRELADR WQIRRYGFHG TSHRYVSEQA AAFLDRPLRG LKQIVLHLGN GCSASAIAGT RPLDTSMGLT PLEGLVMGTR SGDIDPSVVS YLCHTAGMGV DDVESMLNHR SGVVGLSGVR DFRRLRELIE SGDGAAQLAY SVFTHRLRKY IGAYLAVLGH TDVISFTAGI GENDAAVRRD AVSGMEELGI VLDERRNLPG AKGARQISAD DSPITVLVVP TNEELAIARD CVRVLGG
NT Sequence
GTGGACGGTA GCGACGGCGC GCGCCGGGTG CTGGTGATCA ACTCCGGCTC GTCGTCGCTG AAGTTCCAGC TGGTCGATCC CGAGTCCGGG GTGGCCGCCT CGACGGGCAT CGTGGAACGC ATCGGCGAGG AATCCTCGCC GGTCCCCGAC CACGACGCCG CGCTGCGCCG AGCGTTCGAC ATGCTGGCCG GCGACGGCGT CGACCTGAAC ACCGCCGGGC TGGTCGCGGT GGGTCATCGG GTGGTGCACG GCGGCAACAC CTTCTACCGG CCCACCGTGC TGGACGACGC GGTGATCGCC CGGCTGCACG AGCTGTCGGA GTTGGCCCCG CTGCACAATC CGCCGGCGCT CCTGGGGATC GAAGTGGCCC GCAGGCTGCT GCCCGGCATC GCGCACGTGG CCGTCTTCGA CACCGGGTTC TTCCACGACC TGCCGCCCGC GGCGGCGACC TACGCCATCG ACCGCGAACT GGCCGACCGC TGGCAGATCC GCCGGTACGG GTTCCACGGC ACCTCGCACC GCTACGTCAG CGAGCAGGCC GCGGCTTTCC TGGATCGGCC GCTGCGCGGC CTGAAACAGA TCGTGCTGCA CCTGGGCAAC GGCTGCTCGG CGTCAGCGAT CGCCGGCACC CGGCCCCTCG ACACCTCGAT GGGGTTGACG CCGCTGGAGG GACTGGTGAT GGGTACCCGC AGCGGTGACA TCGATCCCAG CGTCGTCAGC TATCTGTGCC ACACGGCCGG GATGGGGGTG GACGACGTCG AGTCGATGCT CAACCACCGC TCGGGGGTGG TCGGGCTGTC CGGCGTGCGG GACTTCCGCC GGCTGCGCGA ACTCATCGAA TCCGGGGACG GCGCAGCGCA ATTGGCCTAC AGCGTGTTCA CGCACCGGCT GCGCAAGTAC ATCGGTGCCT ACCTGGCGGT GCTGGGCCAC ACCGACGTCA TCAGCTTCAC CGCCGGCATC GGTGAGAACG ACGCCGCGGT GCGCCGCGAC GCGGTGTCGG GCATGGAGGA GCTGGGCATT GTGCTCGACG AGCGCCGCAA CCTGCCCGGG GCCAAAGGGG CACGCCAGAT CTCGGCCGAC GACTCGCCGA TCACGGTGCT GGTGGTCCCC ACCAACGAAG AGCTGGCCAT CGCCCGTGAC TGCGTGCGGG TGCTAGGCGG A