NIAID Emerging and Re-emerging Infectious Diseases NIAID Bioinformatics Resource Centers NIAID Structural Genomic Centers Center for Structural Genomics of Infectious Disease
Seattle Structural Genomics Center for Infectious Disease

MygeA.00058.b: Dihydrolipoyl dehydrogenase (MG_271)

Target Characteristics

from organism: Mycoplasma genitalium ATCC 33530 / G-37 / NCTC 10195
most recent status: target approved
center reference id: MygeA.00058.b
is community request: False
associated disease:
NIH risk group: unclassified
is select agent: False
NIH priority
pathogens category:
C

Ordering Clones & Proteins

If there are materials available for this target, they will be listed below. Materials can be ordered from SSGCID using the button in the "order material" column. Clicking the button will add the material to a virtual cart. You may order multiple materials at a time at no cost to you, as this contract is funded by NIAID. When you are ready to place your order, click the "Place Order" link which will appear in the top right corner of the page after you place your first item in your cart.

Molecular models

Method Results
comparative modelling Robetta_10504

External Resources

Resource Reference ID
PATRIC ID: fig|243273.25.peg.313
UniProt: P47513

Enzyme & Pathway Information

Pathway Pathway ID EC Number
N10-formyl-tetrahydrofolate biosynthesis 1CMET2-PWY 1.8.1.4
respiration (anaerobic) ANARESP1-PWY 1.8.1.4
glycine biosynthesis II GLYCINE-SYN2-PWY 1.8.1.4
glycine cleavage GLYCLEAV-PWY 1.8.1.4
superpathway of glycolysis, pyruvate dehydrogenase, TCA, and glyoxylate bypass GLYCOLYSIS-TCA-GLYOX-BYPASS 1.8.1.4
L-isoleucine degradation I ILEUDEG-PWY 1.8.1.4
L-leucine degradation I LEU-DEG2-PWY 1.8.1.4
pyruvate fermentation to acetate and (S)-lactate I P41-PWY 1.8.1.4
photorespiration PWY-181 1.8.1.4
folate transformations I PWY-2201 1.8.1.4
folate transformations II PWY-3841 1.8.1.4
2-oxoisovalerate decarboxylation to isobutanoyl-CoA PWY-5046 1.8.1.4
2-oxoglutarate decarboxylation to succinyl-CoA PWY-5084 1.8.1.4
superpathway of acetyl-CoA biosynthesis PWY-5173 1.8.1.4
superpathway of cytosolic glycolysis (plants), pyruvate dehydrogenase and TCA cycle PWY-5464 1.8.1.4
pyruvate fermentation to acetate II PWY-5482 1.8.1.4
pyruvate fermentation to acetate V PWY-5537 1.8.1.4
TCA cycle II (plants and fungi) PWY-5690 1.8.1.4
1-butanol autotrophic biosynthesis (engineered) PWY-6886 1.8.1.4
photosynthetic 3-hydroxybutanoate biosynthesis (engineered) PWY-7218 1.8.1.4
TCA cycle VII (acetate-producers) PWY-7254 1.8.1.4
anaerobic energy metabolism (invertebrates, mitochondrial) PWY-7384 1.8.1.4
superpathway of anaerobic energy metabolism (invertebrates) PWY-7389 1.8.1.4
pyruvate decarboxylation to acetyl CoA PYRUVDEHYD-PWY 1.8.1.4
TCA cycle I (prokaryotic) TCA 1.8.1.4
superpathway of glyoxylate bypass and TCA TCA-GLYOX-BYPASS 1.8.1.4
L-valine degradation I VALDEG-PWY 1.8.1.4

Sequences

These sequences are the native gene sequence; sequences of constructs derived from these sequences may differ due to codon optimization or other protocols. To find the specific sequence of any material you may have ordered, click on the "more" button next to the name of that material.
AA Sequence
MDYDLIILGA GPAGYIAAEY AGKHKLKTLV IEKQYFGGVC LNVGCIPTKT LLKRAKIIDY LVHAKDYGIT INGQAKLDWK QLLKQKQEVV DKLVAGVKTI IKGAKVESIE GEATVIDKNK VQVNNTTYTT NNIIVATGSR PRYLTLPGFE KAQQAGFIID STQALALEGV PKKFVVVGGG VIGVEFAFLF ASLGSEVTII QGVDRILEVC DSDVSELISK TLKNKGVQII TNAHVVRAEN NQLFYTVNGV EQSVIGDKIL VSIGRIANTE CLDQLDLKRD HNNKIVLNEK LQTSTTNIYL IGDVNTQMML AHYAYQQGRY AVDQILNQNQ VKPAEKNKCP ACIYTNPEVA FVGYSEMELQ KEKIDYVKSS LPFIYSGKAI ADHETNGFVK MMFNPKTGAI LGGCIIASTA SDIIAELALV MENNLTVFDI ANSISPHPTM NEMVTDVCKK AIFDYFS

NT Sequence
ATGGATTATG ATCTAATTAT TTTGGGTGCT GGCCCTGCTG GTTATATTGC TGCGGAGTAT GCTGGCAAAC ATAAACTTAA AACCCTAGTG ATTGAAAAGC AATACTTTGG TGGGGTGTGT TTAAATGTTG GGTGTATCCC AACTAAAACG TTGTTAAAAA GAGCAAAGAT TATTGATTAT TTAGTTCATG CCAAAGATTA TGGTATCACT ATTAATGGTC AAGCTAAACT TGATTGAAAA CAACTGTTAA AACAAAAACA GGAAGTAGTT GATAAATTAG TTGCAGGGGT AAAAACAATT ATTAAGGGTG CTAAGGTAGA AAGTATTGAA GGTGAAGCTA CTGTTATAGA TAAAAACAAG GTGCAAGTAA ACAACACAAC TTACACCACT AACAACATTA TTGTTGCAAC CGGATCAAGA CCAAGATACT TAACTTTACC AGGGTTTGAA AAAGCACAAC AAGCTGGGTT TATCATTGAC TCAACCCAAG CTTTGGCTTT AGAGGGAGTA CCTAAGAAGT TTGTTGTAGT TGGGGGAGGT GTGATTGGGG TTGAGTTTGC TTTTTTATTT GCTTCATTAG GGAGTGAAGT GACCATTATC CAAGGTGTTG ATAGGATTTT GGAGGTTTGT GATAGTGATG TTTCTGAACT GATAAGTAAA ACCTTAAAAA ACAAAGGAGT TCAGATTATT ACCAATGCTC ATGTTGTTAG AGCTGAAAAC AACCAACTGT TTTACACAGT TAATGGAGTT GAACAGTCTG TAATTGGTGA TAAAATCTTA GTTTCTATAG GAAGAATTGC TAACACAGAG TGTTTAGATC AACTTGATTT AAAACGTGAC CATAACAACA AAATTGTTTT AAATGAAAAA CTACAAACAT CAACTACAAA CATCTATCTA ATAGGTGATG TTAACACGCA AATGATGTTG GCACACTACG CTTACCAACA GGGCAGATAT GCTGTTGATC AAATTTTGAA CCAAAACCAG GTAAAGCCTG CTGAAAAAAA CAAGTGTCCT GCTTGTATTT ACACAAATCC TGAAGTTGCT TTTGTAGGTT ATAGTGAGAT GGAATTGCAA AAAGAAAAGA TTGATTATGT CAAATCTTCC TTGCCATTTA TTTATAGTGG TAAAGCAATT GCAGATCATG AAACCAATGG GTTTGTCAAG ATGATGTTTA ATCCTAAAAC TGGTGCTATC TTAGGTGGAT GTATTATTGC TAGCACTGCT AGTGATATTA TCGCTGAGCT TGCTTTGGTG ATGGAAAACA ACCTCACTGT GTTTGATATT GCCAATTCTA TCTCACCCCA TCCTACCATG AATGAAATGG TAACTGATGT TTGTAAAAAA GCGATCTTTG ATTACTTTAG T

© 2020 Seattle Children's Research Institute. All rights reserved.