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Seattle Structural Genomics Center for Infectious Disease

MyleA.01026.a: Putative 4-aminobutyrate aminotransferase

Target Characteristics

from organism: Mycobacterium leprae Br4923
most recent status: expressed
center reference id: MyleA.01026.a
is community request: False
associated disease: Hansen's disease, leprosy
NIH risk group: 2
is select agent: False
NIH priority
pathogens category:
IIIC

Ordering Clones & Proteins

If there are materials available for this target, they will be listed below. Materials can be ordered from SSGCID using the button in the "order material" column. Clicking the button will add the material to a virtual cart. You may order multiple materials at a time at no cost to you, as this contract is funded by NIAID. When you are ready to place your order, click the "Place Order" link which will appear in the top right corner of the page after you place your first item in your cart.

Clones*

CENTER
REFERENCE ID
DOMAIN/REGION
DESCRIPTION
INFO AA
START
AA
STOP
ORDER
MATERIAL
MyleA.01026.a.A1.GE34936 Full length( MyleA.01026.a ) 1 446 GE34936
* SSGCID clones represent un-induced expression constructs which have been verified by sequencing from vector primers. Clones may contain a tag, such as N-term 6xHis. Get sequence information using the button in the "info" column.

External Resources

Resource Reference ID
OrthoMCL: OG5_128761
PATRIC ID: fig|561304.4.peg.845
RefSeq: YP_002503056.1
UniProt: A0A0H3MPK5

Enzyme & Pathway Information

Pathway Pathway ID EC Number
superpathway of 4-aminobutanoate degradation 4AMINOBUTMETAB-PWY 2.6.1.19
superpathway of L-arginine, putrescine, and 4-aminobutanoate degradation ARGDEG-PWY 2.6.1.19
beta-alanine degradation I BETA-ALA-DEGRADATION-I-PWY 2.6.1.19
GABA shunt GLUDEG-I-PWY 2.6.1.19
superpathway of L-arginine and L-ornithine degradation ORNARGDEG-PWY 2.6.1.19
nicotine degradation I (pyridine pathway) P181-PWY 2.6.1.19
glutamate degradation IX (via 4-aminobutyrate) PWY3O-210 2.6.1.19
L-glutamate degradation IV PWY-4321 2.6.1.19
4-aminobutanoate degradation V PWY-5022 2.6.1.19
4-aminobutanoate degradation I PWY-6535 2.6.1.19
4-aminobutanoate degradation III PWY-6536 2.6.1.19
4-aminobutanoate degradation II PWY-6537 2.6.1.19

Sequences

These sequences are the native gene sequence; sequences of constructs derived from these sequences may differ due to codon optimization or other protocols. To find the specific sequence of any material you may have ordered, click on the "more" button next to the name of that material.
AA Sequence
MTSVEQSRQL VTEIPGPVSL ELAKRLNAAV PRGVGVTLPV FVTRAAGGVI EDVDGNRLID LGSGIAVTTI GNSSPRVVDA VRAQVADFTH TCFIITPYEE YVAVTEQLNR ITPGSGEKRS VLFNSGAEAV ENSIKVARSY TRKPAVVAFD HAYHGRTNLT MALTAKSMPY KSGFGPFAPE IYRAPLSYPY RDGLLNKDLA TDGKLAGARA INVIEKQVGA DDLAAVIIEP IQGEGGFIVP AEGFLATLLD WCRKNNVMFI ADEVQTGFAR TGAMFACEHD GIVPDLICTA KGIADGLPLA AVTGRAEIMN APHVSGLGGT FGGNPVACAA ALATITTIEN DGLIQRAQQI ERLITDRLLR LQDADDRIGD VRGRGAMIAV ELVKSGTAEP DPELTEKVAT AAHATGVIIL TCGMFGNIIR LLPPLTISDE LLAEGLDILS RILGDF

NT Sequence
GTGACCAGCG TCGAGCAGAG CCGTCAGCTG GTCACTGAAA TCCCCGGCCC CGTGTCACTT GAACTAGCCA AACGCCTCAA CGCGGCGGTG CCTCGTGGGG TGGGAGTCAC CCTGCCAGTG TTTGTAACGC GCGCCGCCGG CGGCGTTATC GAGGACGTCG ACGGGAACCG GCTTATCGAC CTGGGTTCTG GAATCGCCGT CACCACAATC GGCAACTCGT CGCCTCGCGT TGTGGACGCG GTGCGCGCCC AGGTGGCCGA CTTTACCCAC ACCTGTTTCA TAATCACACC TTACGAGGAG TACGTCGCCG TCACCGAGCA ACTCAATCGA ATTACCCCAG GATCCGGCGA GAAACGCTCG GTGCTGTTCA ATTCCGGCGC CGAGGCAGTG GAGAATTCTA TCAAGGTCGC ACGTTCGTAC ACCCGCAAGC CCGCAGTGGT CGCGTTCGAC CACGCCTACC ACGGTCGCAC CAACCTGACA ATGGCACTGA CCGCCAAGTC CATGCCGTAC AAAAGCGGCT TTGGTCCTTT TGCGCCGGAG ATCTACCGGG CGCCGCTGTC CTACCCCTAT CGGGACGGCC TGCTCAACAA AGACCTAGCC ACCGACGGCA AGTTGGCCGG CGCACGGGCC ATCAACGTCA TTGAGAAGCA GGTTGGCGCC GATGACCTGG CTGCCGTGAT CATTGAGCCG ATCCAGGGCG AAGGCGGTTT CATCGTCCCG GCCGAAGGGT TTTTAGCTAC TTTGCTGGAT TGGTGCCGCA AGAACAACGT GATGTTCATC GCCGATGAGG TGCAAACGGG GTTTGCGCGT ACCGGCGCCA TGTTCGCCTG CGAGCACGAT GGAATCGTGC CCGACCTGAT CTGCACCGCC AAGGGCATCG CCGACGGATT GCCGCTGGCG GCGGTAACCG GACGGGCTGA GATCATGAAC GCCCCGCACG TCAGCGGCCT CGGTGGCACT TTCGGCGGCA ACCCGGTCGC CTGCGCGGCG GCTTTGGCAA CCATCACGAC CATCGAGAAC GACGGCCTGA TCCAGCGAGC CCAACAGATC GAACGGCTGA TCACCGACCG GTTGTTGCGA CTTCAGGACG CCGACGATCG GATAGGTGAC GTACGTGGCC GGGGTGCCAT GATCGCCGTC GAATTGGTAA AATCCGGCAC GGCTGAGCCC GACCCCGAGC TGACCGAAAA AGTAGCCACC GCAGCACACG CTACCGGCGT CATCATCTTG ACGTGTGGCA TGTTCGGCAA CATCATCCGA CTGCTGCCGC CTCTGACCAT AAGCGACGAA CTGTTGGCCG AAGGCCTTGA CATCCTAAGC CGGATCCTGG GTGACTTC

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