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Seattle Structural Genomics Center for Infectious Disease

MyleA.01625.a: S-adenosylmethionine synthetase

Target Characteristics

from organism: Mycobacterium leprae Br4923
most recent status: expressed
center reference id: MyleA.01625.a
is community request: False
associated disease: Hansen's disease, leprosy
NIH risk group: 2
is select agent: False
NIH priority
pathogens category:
IIIC

Ordering Clones & Proteins

If there are materials available for this target, they will be listed below. Materials can be ordered from SSGCID using the button in the "order material" column. Clicking the button will add the material to a virtual cart. You may order multiple materials at a time at no cost to you, as this contract is funded by NIAID. When you are ready to place your order, click the "Place Order" link which will appear in the top right corner of the page after you place your first item in your cart.

Clones*

CENTER
REFERENCE ID
DOMAIN/REGION
DESCRIPTION
INFO AA
START
AA
STOP
ORDER
MATERIAL
MyleA.01625.a.A1.GE29271 Full length( MyleA.01625.a ) 1 403 GE29271
* SSGCID clones represent un-induced expression constructs which have been verified by sequencing from vector primers. Clones may contain a tag, such as N-term 6xHis. Get sequence information using the button in the "info" column.

External Resources

Resource Reference ID
OrthoMCL: OG5_126734
PATRIC ID: fig|561304.4.peg.940
RefSeq: YP_002503094.1
UniProt: B8ZUM2

Enzyme & Pathway Information

Pathway Pathway ID EC Number
ethylene biosynthesis I (plants) ETHYL-PWY 2.5.1.6
L-methionine degradation I (to L-homocysteine) METHIONINE-DEG1-PWY 2.5.1.6
superpathway of S-adenosyl-L-methionine biosynthesis MET-SAM-PWY 2.5.1.6
aspartate superpathway PWY0-781 2.5.1.6
S-adenosyl-L-methionine cycle II PWY-5041 2.5.1.6
superpathway of L-methionine salvage and degradation PWY-5328 2.5.1.6
2'-deoxymugineic acid phytosiderophore biosynthesis PWY-5912 2.5.1.6
S-adenosyl-L-methionine cycle I PWY-6151 2.5.1.6
superpathway of L-cysteine biosynthesis (mammalian) PWY-6292 2.5.1.6
L-methionine salvage cycle II (plants) PWY-7270 2.5.1.6
L-methionine salvage cycle III PWY-7527 2.5.1.6
L-methionine salvage cycle I (bacteria and plants) PWY-7528 2.5.1.6
L-cysteine biosynthesis VI (from L-methionine) PWY-I9 2.5.1.6
S-adenosyl-L-methionine biosynthesis SAM-PWY 2.5.1.6

Sequences

These sequences are the native gene sequence; sequences of constructs derived from these sequences may differ due to codon optimization or other protocols. To find the specific sequence of any material you may have ordered, click on the "more" button next to the name of that material.
AA Sequence
MSEKGRLFTS ESVTEGHPDK ICDAISDSIL DALLAEDPCS RVAVETLVTT GQVHVVGEVT TLAKTAFADI SNTVRERILD IGYDSSDKGF DGASCGVNIG IGAQSSDIAQ GVNTAHEVRV EGAADPLDAQ GAGDQGLMFG YAINDTPELM PLPIALAHRL ARRLTEVRKN GVLPYLRSDG KTQVTIAYED NVPVRLDTVV ISTQHAAGVD LDATLAPDIR EKVLNTVIDD LSHDTLDVSS VRVLVNPTGK FVLGGPMGDA GLTGRKIIVD TYGGWARHGG GAFSGKDPSK VDRSAAYAMR WVAKNIVAAG LAERIEVQVA YAIGKAAPVG LFVETFGTEA VDPAKIEKAI GEVFDLRPGA IIRDLHLLRP IYAQTAAYGH FGRTDVELPW EQLNKVDDLK RAI

NT Sequence
GTGAGTGAGA AGGGTCGGCT GTTCACTAGC GAGTCGGTGA CTGAGGGACA TCCCGACAAG ATCTGTGATG CGATCAGCGA CTCGATCCTT GACGCACTTT TGGCGGAGGA TCCTTGCTCA CGTGTCGCGG TCGAGACGTT GGTCACCACC GGGCAGGTGC ATGTGGTGGG TGAAGTGACG ACGTTGGCCA AGACGGCGTT CGCTGATATC AGTAATACGG TCCGCGAACG TATTCTCGAT ATCGGCTACG ACTCGTCGGA CAAGGGCTTC GATGGGGCGT CGTGCGGAGT TAACATTGGC ATCGGCGCTC AGTCGTCTGA CATTGCTCAA GGCGTCAATA CCGCCCATGA AGTACGCGTC GAGGGCGCGG CGGATCCGCT GGACGCCCAG GGTGCTGGTG ACCAAGGCCT GATGTTCGGT TACGCGATCA ATGACACCCC GGAACTGATG CCGCTACCGA TTGCACTGGC CCACCGACTG GCGCGAAGGC TGACCGAGGT ACGCAAGAAC GGCGTGCTGC CCTACCTGCG TTCCGACGGC AAGACCCAGG TCACTATCGC CTACGAGGAC AATGTCCCAG TGCGTTTGGA CACTGTGGTC ATCTCCACTC AGCACGCCGC TGGTGTCGAC CTGGATGCCA CGCTGGCTCC TGATATCCGG GAGAAGGTGC TCAACACCGT TATTGACGAT CTGTCTCATG ACACCTTGGA TGTATCGTCG GTGCGGGTGC TGGTAAACCC GACCGGCAAG TTCGTGCTAG GTGGGCCGAT GGGCGATGCC GGGCTCACCG GTCGCAAGAT CATCGTCGAC ACCTACGGTG GCTGGGCGCG TCACGGCGGC GGCGCCTTCT CTGGCAAGGA TCCGTCCAAG GTGGACCGGT CGGCAGCCTA CGCGATGCGC TGGGTGGCCA AGAACATCGT CGCTGCCGGG CTGGCGGAGC GAATCGAGGT GCAGGTGGCA TACGCCATCG GCAAAGCCGC CCCGGTCGGT TTGTTCGTCG AGACCTTTGG CACTGAGGCG GTCGATCCGG CCAAAATCGA GAAAGCCATC GGCGAGGTGT TCGATCTGCG TCCCGGCGCG ATCATCCGCG ACCTGCATCT GCTGCGCCCA ATTTACGCGC AAACCGCTGC CTATGGGCAC TTCGGTCGCA CTGACGTCGA ACTGCCATGG GAGCAGCTCA ACAAAGTCGA CGATCTCAAG CGCGCCATC

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