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Seattle Structural Genomics Center for Infectious Disease

MyleA.01655.a: Thymidylate synthase thyX

Target Characteristics

from organism: Mycobacterium leprae Br4923
most recent status: soluble
center reference id: MyleA.01655.a
is community request: True
associated disease: Hansen's disease, leprosy
NIH risk group: 2
is select agent: False
NIH priority
pathogens category:
IIIC

Ordering Clones & Proteins

If there are materials available for this target, they will be listed below. Materials can be ordered from SSGCID using the button in the "order material" column. Clicking the button will add the material to a virtual cart. You may order multiple materials at a time at no cost to you, as this contract is funded by NIAID. When you are ready to place your order, click the "Place Order" link which will appear in the top right corner of the page after you place your first item in your cart.

External Resources

Resource Reference ID
OrthoMCL: OG5_136913
PATRIC ID: fig|561304.4.peg.2849
RefSeq: YP_002503691.1
UniProt: B8ZRR4

Enzyme & Pathway Information

Pathway Pathway ID EC Number
pyrimidine deoxyribonucleotides de novo biosynthesis III PWY-6545 2.1.1.148

Sequences

These sequences are the native gene sequence; sequences of constructs derived from these sequences may differ due to codon optimization or other protocols. To find the specific sequence of any material you may have ordered, click on the "more" button next to the name of that material.
AA Sequence
MAQIAPLRVQ LIAKTEFLAP PDVSWTTDAD GGSALVEFAG RACYQSWSKP NPRTATNAAY IKHIIDVGHV AVLEHASVSF YISGISRSCT HELIRHRHFS YSQLSQRYVP EKDAQVVVPP DMEDDDELQQ ILIAAVEASR ATYTELLVKL NAKLMAGELG GNRAVLRRKQ ARQAAHAVLP NANETRIVVT GNYRAWRHFI AMRASEHADV EIRRLAIVCL RRLVDVAPAV FADFEITALA DGTEVATSPL ATEA

NT Sequence
GTGGCCCAGA TCGCGCCGCT ACGCGTGCAA CTAATTGCCA AGACTGAGTT TCTGGCGCCT CCTGACGTGT CGTGGACTAC CGACGCCGAC GGTGGTTCCG CGCTGGTCGA ATTCGCCGGT CGCGCCTGTT ATCAGAGCTG GTCGAAGCCC AATCCCCGGA CCGCGACCAA CGCCGCGTAC ATTAAACACA TCATTGACGT CGGGCATGTT GCGGTGCTCG AGCATGCCAG CGTTTCGTTC TATATCAGCG GCATCTCGCG ATCATGCACT CACGAGCTGA TCCGACATCG GCATTTCTCC TACTCTCAGC TGTCGCAGCG CTACGTGCCG GAAAAGGATG CCCAGGTCGT TGTGCCACCG GACATGGAGG ATGACGACGA ACTTCAACAG ATTCTGATTG CGGCCGTAGA GGCCAGCCGG GCCACCTACA CTGAACTGCT GGTCAAGCTG AACGCCAAGT TAATGGCCGG TGAGCTCGGC GGGAATAGGG CGGTGTTGCG GCGCAAGCAA GCTCGCCAAG CTGCCCACGC GGTGCTGCCC AACGCCAACG AGACCCGGAT CGTTGTGACC GGGAACTACC GGGCATGGCG GCACTTCATC GCCATGCGGG CCAGCGAGCA CGCCGACGTC GAAATCCGGC GGCTGGCCAT TGTCTGCCTG CGCCGGCTCG TCGACGTTGC GCCCGCAGTA TTCGCTGATT TCGAGATCAC CGCACTTGCT GATGGTACTG AGGTCGCAAC TAGTCCTTTA GCCACCGAAG CT

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