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Seattle Structural Genomics Center for Infectious Disease

MymaA.00471.a: 2-hydroxyhepta-2,4-diene-1,7-dioate isomerase

Target Characteristics

from organism: Mycobacterium marinum ATCC BAA-535 / M
most recent status: in PDB
center reference id: MymaA.00471.a
is community request: False
associated disease: Cutaneous ulcerations, deep abscesses
NIH risk group: 2
is select agent: False
NIH priority
pathogens category:
IIIC

Ordering Clones & Proteins

If there are materials available for this target, they will be listed below. Materials can be ordered from SSGCID using the button in the "order material" column. Clicking the button will add the material to a virtual cart. You may order multiple materials at a time at no cost to you, as this contract is funded by NIAID. When you are ready to place your order, click the "Place Order" link which will appear in the top right corner of the page after you place your first item in your cart.

Clones*

CENTER
REFERENCE ID
DOMAIN/REGION
DESCRIPTION
INFO AA
START
AA
STOP
ORDER
MATERIAL
MymaA.00471.a.A1.GE30029 Full length( MymaA.00471.a ) 1 265 GE30029
* SSGCID clones represent un-induced expression constructs which have been verified by sequencing from vector primers. Clones may contain a tag, such as N-term 6xHis. Get sequence information using the button in the "info" column.

Proteins

CENTER
REFERENCE ID
DOMAIN/REGION
DESCRIPTION
INFO AA
START
AA
STOP
ORDER
MATERIAL
MymaA.00471.a.A1.PS00830 Full length( MymaA.00471.a ) 1 265

Structures

image of structure for 3QDF
3QDF
Deposited: 1/18/2011
Determination: XRay
Diffraction Image
Clone: MymaA.00471.a.A1.GE30029
Protein: MymaA.00471.a.A1.PS00830

Publications by SSGCID

Increasing the structural coverage of tuberculosis drug targets.
Abendroth J, Abramov A, Armour B, Barrett LK, Baugh L, Begley DW, Buchko GW, Choi R, Clifton MC, Dieterich SH, Dranow DM, Edwards TE, Fairman JW, Ferrell M, Fox D, Gardberg AS, Hewitt SN, Lorimer D, Lyons-Abbott S, Mundt E, Muruthi MM, Myers J, Myler PJ, Napuli AJ, Phan I, Sekar A, Serbzhinskiy D, Stacy R, Staker BL, Stewart LJ, Taylor BM, Thompkins K, Tran N, Van Voorhis WC, Zhang Y
Tuberculosis (Edinb) - 2014
volume 95, issue 2, pages 142-8
PMID: 25613812; PMCID: PMC4361283
PDB: 3GVC, 3GVG, 3GWC, 3H7F, 3H81, 3HE2, 3HWI, 3HWK, 3HZG, 3ICO, 3KHP, 3LLS, 3MOY, 3MPZ, 3MYB, 3NDN, 3NDO, 3NF4, 3NG3, 3NJD, 3NWO, 3O0M, 3O38, 3OC6, 3OC7, 3OEC, 3OI9, 3OKS, 3OL3, 3OL4, 3OME, 3P0T, 3P2Y, 3P4I, 3P4T, 3P5M, 3P85, 3PE8, 3PGX, 3PK0, 3PPI, 3PXX, 3PZY, 3Q1T, 3Q8N, 3QBP, 3QDF, 3QH4, 3QHA, 3QIV, 3QK8, 3QKA, 3QLJ, 3QMJ, 3QRE, 3QUA, 3QUV, 3QXI, 3QXZ, 3QYR, 3R0O, 3R1I, 3R1J, 3R20, 3R2N, 3R4T, 3R6H, 3R6O, 3R7K, 3R8C, 3R9P, 3R9Q, 3R9R, 3R9S, 3R9T, 3RD5, 3RD7, 3RD8, 3RFQ, 3RIH, 3RR2, 3RR6, 3RRP, 3RRV, 3RSI, 3RV2, 3S55, 3S82, 3SBX, 3SF6, 3SLL, 3SVK, 3SVT, 3SWO, 3SWT, 3SWX, 3SX2, 3T3W, 3T7C, 3TAV, 3TCR, 3TDE, 3TJR, 3TL3, 3TLF, 3TRR, 3TSC, 3TX2, 3TZQ, 3TZU, 3U0A, 3U0B, 3UCX, 3UVE, 4DI1, 4DIE, 4DQ8, 4DXL, 4ED4, 4EGE, 4EGF, 4EMD, 4EO9, 4EYE, 4F3W, 4F47, 4FFC, 4GK6, 4HDT, 4HR3, 4I1Y, 4IJN, 4IV6, 4IZ9, 4J5I, 4KAM, 4LGV, 4O2D, 5EJ2

Citations by Others

Crystal structures of Cg1458 reveal a catalytic lid domain and a common catalytic mechanism for the FAH family
R Tingting, G Yanyan, M May, Z Wenjun? - Biochemical Journal, 2013 - biochemj.org
PDB: 3QDF
Expression, purification, crystallization and preliminary crystallographic analysis of Cg1458: a novel oxaloacetate decarboxylase from Corynebacterium glutamicum
T Ran, Y Wang, D Xu, W Wang - Acta Crystallographica Section F Structural Biology and Crystallization Communications, 2011 - scripts.iucr.org
cited by: 2 others
PDB: 3QDF

This list was obtained from Google Scholar searches using the Open Source tool https://github.com/ckreibich/scholar.py and each citation has been manually reviewed.

External Resources

Resource Reference ID
OrthoMCL: OG5_126763
PATRIC ID: fig|216594.6.peg.1838
RefSeq: YP_001850022.1
UniProt: B2HIH3

Sequences

These sequences are the native gene sequence; sequences of constructs derived from these sequences may differ due to codon optimization or other protocols. To find the specific sequence of any material you may have ordered, click on the "more" button next to the name of that material.
AA Sequence
MRLGRIASPD GVAFASIEGE LDNPGAMTAR EIAEHPFGTP NFTGRSWPLA DVRLLAPILA SKVVCVGKNY TDHIAEMGGQ TGPTPADPVI FLKPNTAIVG PNVPIRLPAN ASPVHFEGEL AIVIGRPCKD VSAAQAVDNI LGYTIGNDVS ARDQQKSDGQ WTRAKGHDTF CPVGPWIVTD VDPADLELRT EVNGAVKQHA RTSLMIHDVG AIVEWISAVM TLLPGDLILT GTPAGVGPIE DGDTVSITIE GIGTLTNPVV RKGKS

NT Sequence
ATGCGCCTTG GACGTATTGC CAGCCCTGAC GGGGTCGCCT TCGCCAGCAT CGAAGGCGAG TTAGACAATC CGGGTGCGAT GACCGCCCGG GAGATCGCGG AGCACCCTTT CGGGACGCCG AACTTCACCG GCCGCTCGTG GCCGTTGGCC GATGTGCGGC TGCTGGCCCC GATACTTGCC AGCAAGGTGG TCTGTGTCGG CAAGAACTAC ACCGATCACA TCGCGGAGAT GGGCGGCCAA ACCGGTCCGA CGCCGGCGGA TCCGGTGATA TTCCTCAAGC CCAACACGGC GATCGTCGGT CCGAACGTGC CGATTCGGTT GCCCGCCAAC GCATCACCAG TCCACTTCGA AGGCGAACTG GCGATTGTGA TCGGCCGGCC GTGTAAGGAC GTCTCGGCCG CGCAGGCGGT CGACAACATC CTCGGCTACA CCATCGGCAA TGACGTGTCC GCCCGCGATC AGCAGAAATC CGACGGGCAA TGGACCCGGG CCAAAGGCCA TGACACATTC TGTCCGGTCG GGCCATGGAT CGTTACCGAT GTCGACCCTG CCGACCTCGA ACTGCGCACC GAAGTCAATG GTGCGGTCAA GCAGCACGCG CGTACCTCGC TGATGATCCA CGATGTGGGT GCCATCGTGG AGTGGATCTC GGCGGTAATG ACATTGCTGC CCGGTGATCT CATCCTCACC GGAACACCCG CGGGGGTCGG TCCCATCGAA GACGGTGACA CCGTCTCCAT CACCATCGAG GGGATCGGCA CCCTGACCAA CCCCGTAGTC CGTAAAGGAA AGTCG

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