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Seattle Structural Genomics Center for Infectious Disease

MymaA.00556.a: Succinyl-CoA ligase [ADP-forming] subunit alpha

Target Characteristics

from organism: Mycobacterium marinum ATCC BAA-535 / M
most recent status: cloned
center reference id: MymaA.00556.a
is community request: False
associated disease: Cutaneous ulcerations, deep abscesses
NIH risk group: 2
is select agent: False
NIH priority
pathogens category:
IIIC

Ordering Clones & Proteins

If there are materials available for this target, they will be listed below. Materials can be ordered from SSGCID using the button in the "order material" column. Clicking the button will add the material to a virtual cart. You may order multiple materials at a time at no cost to you, as this contract is funded by NIAID. When you are ready to place your order, click the "Place Order" link which will appear in the top right corner of the page after you place your first item in your cart.

External Resources

Resource Reference ID
OrthoMCL: OG5_127106
PATRIC ID: fig|216594.6.peg.4888
RefSeq: YP_001852810.1
UniProt: B2HED0

Enzyme & Pathway Information

Pathway Pathway ID EC Number
superpathway of glycolysis, pyruvate dehydrogenase, TCA, and glyoxylate bypass GLYCOLYSIS-TCA-GLYOX-BYPASS 6.2.1.5
reductive TCA cycle I P23-PWY 6.2.1.5
incomplete reductive TCA cycle P42-PWY 6.2.1.5
reductive TCA cycle II PWY-5392 6.2.1.5
superpathway of cytosolic glycolysis (plants), pyruvate dehydrogenase and TCA cycle PWY-5464 6.2.1.5
pyruvate fermentation to acetate V PWY-5537 6.2.1.5
pyruvate fermentation to acetate VI PWY-5538 6.2.1.5
TCA cycle II (plants and fungi) PWY-5690 6.2.1.5
partial TCA cycle (obligate autotrophs) PWY-5913 6.2.1.5
Methanobacterium thermoautotrophicum biosynthetic metabolism PWY-6146 6.2.1.5
TCA cycle III (animals) PWY66-398 6.2.1.5
methylaspartate cycle PWY-6728 6.2.1.5
TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase) PWY-6969 6.2.1.5
anaerobic energy metabolism (invertebrates, mitochondrial) PWY-7384 6.2.1.5
superpathway of anaerobic energy metabolism (invertebrates) PWY-7389 6.2.1.5
TCA cycle I (prokaryotic) TCA 6.2.1.5
superpathway of glyoxylate bypass and TCA TCA-GLYOX-BYPASS 6.2.1.5

Sequences

These sequences are the native gene sequence; sequences of constructs derived from these sequences may differ due to codon optimization or other protocols. To find the specific sequence of any material you may have ordered, click on the "more" button next to the name of that material.
AA Sequence
MSIFLNKDNK VIVQGITGSE ATVHTARMLK AGTQIVGGVN ARKAGTTVTH EDKGGRVIKL PVFGGVAEAM EKTGADVSII FVPPKFAKDA IIEAIDAEIP LLVVITEGIP VQDTAYAWAY NLGKGGKTRI IGPNCPGIIT PGQALVGITP ANITGAGPVG LVSKSGTLTY QMMFELRDFG FTTSIGIGGD PVIGTTHIDA IEAFEKDPDT KLIVMIGEIG GDAEERAADF IKANVSKPVV GYVAGFTAPE GKTMGHAGAI VSGSSGTAAA KKEALEAAGV QVGKTPSETA MLAREILKGL

NT Sequence
ATGTCGATCT TCTTGAACAA GGACAACAAG GTCATCGTCC AGGGCATCAC CGGCAGCGAG GCCACCGTCC ACACTGCGCG CATGCTCAAG GCCGGCACCC AAATCGTCGG CGGGGTGAAC GCGCGCAAGG CGGGCACCAC CGTGACGCAC GAGGACAAGG GCGGCCGGGT AATCAAGCTG CCGGTATTCG GCGGTGTCGC CGAGGCGATG GAAAAGACCG GCGCCGACGT CTCGATCATC TTCGTGCCGC CGAAGTTCGC CAAGGACGCG ATCATCGAGG CCATTGACGC CGAGATTCCG CTGCTGGTGG TCATCACCGA GGGGATCCCG GTGCAAGACA CCGCCTATGC CTGGGCCTAC AACCTGGGCA AGGGCGGCAA GACCCGCATC ATCGGGCCCA ACTGCCCGGG CATCATCACC CCAGGGCAGG CGCTGGTTGG CATCACCCCG GCCAACATCA CCGGCGCCGG CCCGGTCGGG CTGGTCTCCA AGTCCGGCAC GCTGACCTAC CAGATGATGT TCGAGCTGCG CGATTTCGGT TTCACCACCT CGATCGGTAT CGGTGGCGAC CCAGTGATCG GCACCACCCA CATCGATGCC ATCGAGGCGT TCGAGAAGGA TCCCGACACC AAGCTGATCG TGATGATCGG TGAGATCGGT GGGGACGCCG AGGAGCGAGC GGCCGACTTC ATCAAGGCCA ACGTGTCCAA GCCGGTTGTC GGTTACGTGG CGGGATTCAC CGCGCCGGAG GGCAAGACCA TGGGGCACGC GGGTGCCATC GTGTCCGGCT CCTCGGGCAC CGCGGCGGCC AAGAAAGAAG CCCTGGAGGC CGCCGGGGTA CAGGTCGGCA AGACCCCGTC GGAGACCGCG ATGCTGGCCC GGGAGATCCT GAAGGGTCTC

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