NIAID Emerging and Re-emerging Infectious Diseases NIAID Bioinformatics Resource Centers NIAID Structural Genomic Centers Center for Structural Genomics of Infectious Disease
Seattle Structural Genomics Center for Infectious Disease

MymaA.00640.a: Acetate kinase AckA

Target Characteristics

from organism: Mycobacterium marinum ATCC BAA-535 / M
most recent status: in PDB
center reference id: MymaA.00640.a
is community request: False
associated disease: Cutaneous ulcerations, deep abscesses
NIH risk group: 2
is select agent: False
NIH priority
pathogens category:
IIIC

Ordering Clones & Proteins

If there are materials available for this target, they will be listed below. Materials can be ordered from SSGCID using the button in the "order material" column. Clicking the button will add the material to a virtual cart. You may order multiple materials at a time at no cost to you, as this contract is funded by NIAID. When you are ready to place your order, click the "Place Order" link which will appear in the top right corner of the page after you place your first item in your cart.

Clones*

CENTER
REFERENCE ID
DOMAIN/REGION
DESCRIPTION
INFO AA
START
AA
STOP
ORDER
MATERIAL
MymaA.00640.a.A1.GE30052 Full length( MymaA.00640.a ) 1 388 GE30052
* SSGCID clones represent un-induced expression constructs which have been verified by sequencing from vector primers. Clones may contain a tag, such as N-term 6xHis. Get sequence information using the button in the "info" column.

Proteins

CENTER
REFERENCE ID
DOMAIN/REGION
DESCRIPTION
INFO AA
START
AA
STOP
ORDER
MATERIAL
MymaA.00640.a.A1.PW29924 Full length( MymaA.00640.a ) 1 388

Structures

image of structure for 4DQ8
4DQ8
Deposited: 2/15/2012
Determination: XRay
Diffraction Image
Clone: MymaA.00640.a.A1.GE30052
Protein: MymaA.00640.a.A1.PW29924

Publications by SSGCID

Increasing the structural coverage of tuberculosis drug targets.
Abendroth J, Abramov A, Armour B, Barrett LK, Baugh L, Begley DW, Buchko GW, Choi R, Clifton MC, Dieterich SH, Dranow DM, Edwards TE, Fairman JW, Ferrell M, Fox D, Gardberg AS, Hewitt SN, Lorimer D, Lyons-Abbott S, Mundt E, Muruthi MM, Myers J, Myler PJ, Napuli AJ, Phan I, Sekar A, Serbzhinskiy D, Stacy R, Staker BL, Stewart LJ, Taylor BM, Thompkins K, Tran N, Van Voorhis WC, Zhang Y
Tuberculosis (Edinb) - 2014
volume 95, issue 2, pages 142-8
PMID: 25613812; PMCID: PMC4361283
PDB: 3GVC, 3GVG, 3GWC, 3H7F, 3H81, 3HE2, 3HWI, 3HWK, 3HZG, 3ICO, 3KHP, 3LLS, 3MOY, 3MPZ, 3MYB, 3NDN, 3NDO, 3NF4, 3NG3, 3NJD, 3NWO, 3O0M, 3O38, 3OC6, 3OC7, 3OEC, 3OI9, 3OKS, 3OL3, 3OL4, 3OME, 3P0T, 3P2Y, 3P4I, 3P4T, 3P5M, 3P85, 3PE8, 3PGX, 3PK0, 3PPI, 3PXX, 3PZY, 3Q1T, 3Q8N, 3QBP, 3QDF, 3QH4, 3QHA, 3QIV, 3QK8, 3QKA, 3QLJ, 3QMJ, 3QRE, 3QUA, 3QUV, 3QXI, 3QXZ, 3QYR, 3R0O, 3R1I, 3R1J, 3R20, 3R2N, 3R4T, 3R6H, 3R6O, 3R7K, 3R8C, 3R9P, 3R9Q, 3R9R, 3R9S, 3R9T, 3RD5, 3RD7, 3RD8, 3RFQ, 3RIH, 3RR2, 3RR6, 3RRP, 3RRV, 3RSI, 3RV2, 3S55, 3S82, 3SBX, 3SF6, 3SLL, 3SVK, 3SVT, 3SWO, 3SWT, 3SWX, 3SX2, 3T3W, 3T7C, 3TAV, 3TCR, 3TDE, 3TJR, 3TL3, 3TLF, 3TRR, 3TSC, 3TX2, 3TZQ, 3TZU, 3U0A, 3U0B, 3UCX, 3UVE, 4DI1, 4DIE, 4DQ8, 4DXL, 4ED4, 4EGE, 4EGF, 4EMD, 4EO9, 4EYE, 4F3W, 4F47, 4FFC, 4GK6, 4HDT, 4HR3, 4I1Y, 4IJN, 4IV6, 4IZ9, 4J5I, 4KAM, 4LGV, 4O2D, 5EJ2

Citations by Others

Investigation of pyrophosphate versus ATP substrate selection in the Entamoeba histolytica acetate kinase
T Dang, C Ingram-Smith- Scientific Reports, 2017 - ncbi.nlm.nih.gov
PDB: 4DQ8

This list was obtained from Google Scholar searches using the Open Source tool https://github.com/ckreibich/scholar.py and each citation has been manually reviewed.

External Resources

Resource Reference ID
OrthoMCL: OG5_130287
PATRIC ID: fig|216594.6.peg.762
RefSeq: YP_001849025.1
UniProt: B2HPZ3

Enzyme & Pathway Information

Pathway Pathway ID EC Number
(S)-propane-1,2-diol degradation PWY-7013 2.7.2.1
superpathway of L-threonine metabolism THREOCAT-PWY 2.7.2.1

Sequences

These sequences are the native gene sequence; sequences of constructs derived from these sequences may differ due to codon optimization or other protocols. To find the specific sequence of any material you may have ordered, click on the "more" button next to the name of that material.
AA Sequence
MSASRPNRVV LVLNSGSSSL KFQLVEPDSG MSRATGNIER IGEESSSVPD HDAALRRVFE ILAEDDIDLQ SCGLVAVGHR VVHGGKDFYE PTLLNDAVIG KLDELSPLAP LHNPPAVLCI RVARALLPDV PHIAVFDTAF FHQLPPAAAT YAIDRELADV WKIRRYGFHG TSHEYVSQQA AEFLGKPIGD LNQIVLHLGN GASASAVAGG RPVETSMGLT PLEGLVMGTR SGDLDPGVIG YLWRTAKLGV DEIESMLNHR SGMLGLAGER DFRRLRAMID DGDPAAELAY DVFIHRLRKY VGAYLAVLGH TDVVSFTAGI GEHDAAVRRD TLAGMAELGI SLDERRNACP SGGARRISAD DSPVTVLVIP TNEELAIARH CCSVLVAV

NT Sequence
ATGAGCGCTA GCCGTCCGAA TCGTGTTGTG CTGGTCCTCA ACTCTGGATC CTCATCCCTG AAGTTTCAGC TCGTCGAACC CGATTCAGGT ATGTCACGGG CGACCGGAAA CATCGAGCGC ATCGGCGAAG AATCGTCATC GGTGCCCGAC CACGACGCGG CCCTGCGCCG AGTGTTCGAG ATCTTGGCCG AAGACGACAT CGACCTTCAG TCCTGCGGCC TGGTCGCGGT GGGGCATCGG GTAGTGCACG GCGGCAAGGA CTTTTACGAA CCGACGTTGC TCAACGATGC GGTGATCGGC AAGCTCGATG AGCTATCGCC GCTGGCCCCG CTGCACAATC CGCCCGCGGT GTTGTGCATC AGGGTGGCGC GTGCGTTGCT GCCCGACGTG CCGCACATCG CGGTCTTCGA CACCGCCTTC TTTCACCAGC TCCCGCCCGC GGCGGCCACC TACGCCATCG ATCGCGAGTT GGCGGACGTC TGGAAAATTC GCCGCTATGG CTTCCACGGG ACATCCCATG AGTACGTCAG CCAACAAGCC GCGGAATTCC TGGGCAAGCC CATTGGTGAT CTGAATCAGA TTGTGCTGCA TCTGGGTAAC GGCGCGTCGG CTTCAGCGGT TGCGGGAGGA CGGCCGGTGG AGACGTCGAT GGGTCTGACG CCGCTGGAGG GTTTGGTGAT GGGCACCCGC AGTGGTGACT TGGACCCCGG GGTTATTGGA TACCTTTGGC GCACCGCAAA GTTGGGTGTT GATGAGATCG AATCAATGCT CAACCACCGG TCCGGGATGT TGGGGTTGGC AGGCGAGCGG GACTTTCGCC GGCTGAGGGC AATGATCGAC GACGGCGACC CGGCGGCTGA ATTGGCTTAC GACGTCTTCA TTCACCGGCT GCGCAAGTAC GTTGGCGCTT ACCTGGCGGT GCTGGGCCAC ACCGACGTGG TGAGCTTTAC CGCCGGGATC GGCGAGCACG ACGCGGCGGT GCGCCGAGAC ACCCTGGCCG GGATGGCCGA ACTAGGGATC AGCCTGGACG AGCGGCGCAA CGCCTGCCCG TCCGGTGGCG CGCGCCGGAT CTCCGCCGAC GACTCGCCGG TCACCGTTTT GGTGATACCG ACCAACGAAG AACTGGCTAT TGCCCGGCAT TGCTGCTCGG TGTTGGTCGC CGTA

© 2022 Seattle Children's Research Institute. All rights reserved.