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Seattle Structural Genomics Center for Infectious Disease

MymaA.01570.a: 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase FolK (Rv3606c ortholog)

Target Characteristics

from organism: Mycobacterium marinum ATCC BAA-535 / M
most recent status: cloned
center reference id: MymaA.01570.a
is community request: True
associated disease: Cutaneous ulcerations, deep abscesses
NIH risk group: 2
is select agent: False
NIH priority
pathogens category:
IIIC

Ordering Clones & Proteins

If there are materials available for this target, they will be listed below. Materials can be ordered from SSGCID using the button in the "order material" column. Clicking the button will add the material to a virtual cart. You may order multiple materials at a time at no cost to you, as this contract is funded by NIAID. When you are ready to place your order, click the "Place Order" link which will appear in the top right corner of the page after you place your first item in your cart.

External Resources

Resource Reference ID
PATRIC ID: fig|216594.6.peg.5472
RefSeq: YP_001853368.1
UniProt: B2HJ50

Enzyme & Pathway Information

Pathway Pathway ID EC Number
superpathway of chorismate metabolism ALL-CHORISMATE-PWY 2.7.6.3
superpathway of tetrahydrofolate biosynthesis and salvage FOLSYN-PWY 2.7.6.3
6-hydroxymethyl-dihydropterin diphosphate biosynthesis I PWY-6147 2.7.6.3
tetrahydromethanopterin biosynthesis PWY-6148 2.7.6.3
superpathway of tetrahydrofolate biosynthesis PWY-6612 2.7.6.3
6-hydroxymethyl-dihydropterin diphosphate biosynthesis II (Methanocaldococcus) PWY-6797 2.7.6.3
6-hydroxymethyl-dihydropterin diphosphate biosynthesis III (Chlamydia) PWY-7539 2.7.6.3
6-hydroxymethyl-dihydropterin diphosphate biosynthesis IV (Plasmodium) PWY-7852 2.7.6.3
6-hydroxymethyl-dihydropterin diphosphate biosynthesis V (Pyrococcus) PWY-7853 2.7.6.3

Sequences

These sequences are the native gene sequence; sequences of constructs derived from these sequences may differ due to codon optimization or other protocols. To find the specific sequence of any material you may have ordered, click on the "more" button next to the name of that material.
AA Sequence
MSSVVLSVGS NLGDRLANLR SVVDGLGDTL VGASRVYETD PWGGVAQEPF LNVVLIADDP ARDGHAWLHQ AQEFERAAGR QRLQRWGPRT LDVDLVACYQ AGPAGRTEVR CNDSILTLPH PLAHQRAFVM VPWLDVDPAA ELTAPEGPRP VAALLAGLPP ADRASVRLTS LTVAA

NT Sequence
atgagttcgg tagtgctgtc ggtcggttcc aacctgggcg accgcctggc gaacctgcgt tcggtggtcg acggactcgg cgacacgttg gtcggggcgt cgcgtgtcta tgagaccgat ccgtggggtg gggtggccca ggagccgttc ctcaacgtgg tgctgatcgc agacgatccc gctcgcgacg gccatgcctg gttgcaccaa gctcaggagt tcgagcgggc ggccggccgg cagcgtctgc agcggtgggg gccgcgcacg ctcgacgtgg atctggtcgc ctgttaccag gccggcccgg ccggtcgtac cgaagtgcgc tgcaacgaca gcatcctgac gctgccacac ccattggcgc atcagcgggc ctttgtcatg gtcccttggc tcgacgttga ccccgcggcc gaactgaccg caccggaggg cccgcgcccg gttgccgcgc tgctggccgg gctgccgccg gccgatcggg caagcgtgcg gttgacctcg ctgaccgtgg cagcctga

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