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Seattle Structural Genomics Center for Infectious Disease

MypaA.01212.a: Malate dehydrogenase

Target Characteristics

from organism: Mycobacterium paratuberculosis ATCC BAA-968 / K-10
most recent status: crystallized
center reference id: MypaA.01212.a
is community request: False
associated disease: Johne's disease
NIH risk group: 2
is select agent: False
NIH priority
pathogens category:
IIIC

Ordering Clones & Proteins

If there are materials available for this target, they will be listed below. Materials can be ordered from SSGCID using the button in the "order material" column. Clicking the button will add the material to a virtual cart. You may order multiple materials at a time at no cost to you, as this contract is funded by NIAID. When you are ready to place your order, click the "Place Order" link which will appear in the top right corner of the page after you place your first item in your cart.

Clones*

CENTER
REFERENCE ID
DOMAIN/REGION
DESCRIPTION
INFO AA
START
AA
STOP
ORDER
MATERIAL
MypaA.01212.a.A1.GE29562 Full length( MypaA.01212.a ) 1 329 GE29562
* SSGCID clones represent un-induced expression constructs which have been verified by sequencing from vector primers. Clones may contain a tag, such as N-term 6xHis. Get sequence information using the button in the "info" column.

Proteins

CENTER
REFERENCE ID
DOMAIN/REGION
DESCRIPTION
INFO AA
START
AA
STOP
ORDER
MATERIAL
MypaA.01212.a.A1.PW29460 Full length( MypaA.01212.a ) 1 329

External Resources

Resource Reference ID
OrthoMCL: OG5_127410
PATRIC ID: fig|262316.17.peg.2697
RefSeq: NP_961475.1
UniProt: P61976

Enzyme & Pathway Information

Pathway Pathway ID EC Number
respiration (anaerobic) ANARESP1-PWY 1.1.1.37
mixed acid fermentation FERMENTATION-PWY 1.1.1.37
gluconeogenesis I GLUCONEO-PWY 1.1.1.37
superpathway of glycolysis, pyruvate dehydrogenase, TCA, and glyoxylate bypass GLYCOLYSIS-TCA-GLYOX-BYPASS 1.1.1.37
glyoxylate cycle GLYOXYLATE-BYPASS 1.1.1.37
L-aspartate degradation II MALATE-ASPARTATE-SHUTTLE-PWY 1.1.1.37
TCA cycle IV (2-oxoglutarate decarboxylase) P105-PWY 1.1.1.37
pyruvate fermentation to propanoate I P108-PWY 1.1.1.37
reductive TCA cycle I P23-PWY 1.1.1.37
incomplete reductive TCA cycle P42-PWY 1.1.1.37
formaldehyde assimilation I (serine pathway) PWY-1622 1.1.1.37
L-carnitine degradation III PWY-3641 1.1.1.37
L-glutamate degradation VIII (to propanoate) PWY-5088 1.1.1.37
reductive TCA cycle II PWY-5392 1.1.1.37
superpathway of cytosolic glycolysis (plants), pyruvate dehydrogenase and TCA cycle PWY-5464 1.1.1.37
superpathway of glyoxylate cycle and fatty acid degradation PWY-561 1.1.1.37
TCA cycle II (plants and fungi) PWY-5690 1.1.1.37
partial TCA cycle (obligate autotrophs) PWY-5913 1.1.1.37
Methanobacterium thermoautotrophicum biosynthetic metabolism PWY-6146 1.1.1.37
TCA cycle III (animals) PWY66-398 1.1.1.37
gluconeogenesis III PWY66-399 1.1.1.37
methylaspartate cycle PWY-6728 1.1.1.37
TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase) PWY-6969 1.1.1.37
malate-oxaloacetate shuttle I PWY-7047 1.1.1.37
malate-oxaloacetate shuttle II PWY-7048 1.1.1.37
C4 photosynthetic carbon assimilation cycle, NAD-ME type PWY-7115 1.1.1.37
chitin degradation to ethanol PWY-7118 1.1.1.37
anaerobic energy metabolism (invertebrates, cytosol) PWY-7383 1.1.1.37
anaerobic energy metabolism (invertebrates, mitochondrial) PWY-7384 1.1.1.37
superpathway of anaerobic energy metabolism (invertebrates) PWY-7389 1.1.1.37
TCA cycle I (prokaryotic) TCA 1.1.1.37
superpathway of glyoxylate bypass and TCA TCA-GLYOX-BYPASS 1.1.1.37

Sequences

These sequences are the native gene sequence; sequences of constructs derived from these sequences may differ due to codon optimization or other protocols. To find the specific sequence of any material you may have ordered, click on the "more" button next to the name of that material.
AA Sequence
MSASPLKVAV TGAAGQIGYS LLFRLASGSL LGPDRPIELR LLEIEPALKA LEGVVMELDD CAFPLLSGVE IGADPNKIFD GANLALLVGA RPRGPGMERS DLLEANGAIF TAQGKALNEV AADDIRVGVT GNPANTNALI AMSNAPDIPR ERFSALTRLD HNRAISQLAK KTGAKVTDIK KMTIWGNHSA TQYPDIFHAE VKGKNAAEVV GDQNWIENDF IPTVAKRGAA IIDARGASSA ASAASATTDA ARDWLLGTPA GDWVSMAVIS DGSYGVPEGL ISSFPVTTKD GDWTIVQGLE IDEFSRSRID KTTAELADER NAVTQLGLI

NT Sequence
GTGAGCGCAA GTCCTCTCAA GGTTGCCGTC ACCGGCGCCG CCGGCCAGAT CGGCTACAGC CTGTTGTTCC GCCTGGCCAG CGGCTCGTTG CTGGGCCCCG ACCGCCCGAT CGAGCTGCGT CTGCTCGAGA TCGAGCCCGC GCTCAAGGCG CTCGAGGGCG TCGTGATGGA ACTCGACGAC TGCGCCTTCC CGCTGCTGTC CGGCGTCGAG ATCGGCGCCG ACCCGAACAA GATCTTCGAC GGCGCCAACC TCGCGCTGCT GGTCGGCGCG CGGCCGCGCG GCCCGGGCAT GGAGCGCAGC GACCTGCTGG AGGCCAACGG CGCGATCTTC ACCGCGCAGG GCAAGGCGCT CAACGAGGTG GCCGCCGACG ACATCCGCGT CGGCGTGACC GGCAACCCGG CCAACACCAA CGCGTTGATC GCGATGAGCA ACGCCCCGGA CATCCCGCGC GAGCGGTTCT CGGCGCTGAC CCGCCTGGAC CACAACCGGG CCATCTCGCA GCTGGCCAAA AAGACCGGCG CCAAGGTCAC CGACATCAAG AAGATGACGA TCTGGGGCAA CCACTCCGCC ACCCAGTACC CCGATATCTT CCACGCCGAG GTCAAGGGTA AGAACGCGGC CGAGGTGGTG GGCGACCAGA ACTGGATCGA GAACGACTTC ATCCCGACCG TGGCCAAGCG CGGCGCGGCC ATCATCGACG CGCGGGGCGC CTCCTCGGCC GCGTCGGCCG CCTCGGCGAC CACCGACGCC GCCCGCGACT GGCTGCTGGG CACCCCGGCG GGCGACTGGG TCTCCATGGC CGTCATCTCC GACGGCTCCT ACGGCGTGCC GGAGGGGCTG ATCTCGTCGT TCCCGGTGAC CACCAAGGAC GGCGACTGGA CCATCGTGCA GGGCCTGGAG ATCGACGAGT TCTCCCGCAG CCGGATCGAC AAGACCACCG CCGAGCTCGC CGACGAGCGC AACGCGGTGA CCCAGCTCGG CCTGATC

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