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Seattle Structural Genomics Center for Infectious Disease

MypaA.01625.a: S-adenosylmethionine synthetase

Target Characteristics

from organism: Mycobacterium paratuberculosis ATCC BAA-968 / K-10
most recent status: expressed
center reference id: MypaA.01625.a
is community request: False
associated disease: Johne's disease
NIH risk group: 2
is select agent: False
NIH priority
pathogens category:
IIIC

Ordering Clones & Proteins

If there are materials available for this target, they will be listed below. Materials can be ordered from SSGCID using the button in the "order material" column. Clicking the button will add the material to a virtual cart. You may order multiple materials at a time at no cost to you, as this contract is funded by NIAID. When you are ready to place your order, click the "Place Order" link which will appear in the top right corner of the page after you place your first item in your cart.

External Resources

Resource Reference ID
OrthoMCL: OG5_126734
PATRIC ID: fig|262316.17.peg.1185
RefSeq: NP_960060.1
UniProt: Q741G5

Enzyme & Pathway Information

Pathway Pathway ID EC Number
ethylene biosynthesis I (plants) ETHYL-PWY 2.5.1.6
L-methionine degradation I (to L-homocysteine) METHIONINE-DEG1-PWY 2.5.1.6
superpathway of S-adenosyl-L-methionine biosynthesis MET-SAM-PWY 2.5.1.6
aspartate superpathway PWY0-781 2.5.1.6
S-adenosyl-L-methionine cycle II PWY-5041 2.5.1.6
superpathway of L-methionine salvage and degradation PWY-5328 2.5.1.6
2'-deoxymugineic acid phytosiderophore biosynthesis PWY-5912 2.5.1.6
S-adenosyl-L-methionine cycle I PWY-6151 2.5.1.6
superpathway of L-cysteine biosynthesis (mammalian) PWY-6292 2.5.1.6
L-methionine salvage cycle II (plants) PWY-7270 2.5.1.6
L-methionine salvage cycle III PWY-7527 2.5.1.6
L-methionine salvage cycle I (bacteria and plants) PWY-7528 2.5.1.6
L-cysteine biosynthesis VI (from L-methionine) PWY-I9 2.5.1.6
S-adenosyl-L-methionine biosynthesis SAM-PWY 2.5.1.6

Sequences

These sequences are the native gene sequence; sequences of constructs derived from these sequences may differ due to codon optimization or other protocols. To find the specific sequence of any material you may have ordered, click on the "more" button next to the name of that material.
AA Sequence
MSEKGRLFTS ESVTEGHPDK ICDAISDSVL DALLAQDPRS RVAVETLVTT GQVHVVGEVT TTAKEAFADI TNTVRERILD IGYDSSDKGF DGASCGVNIG IGAQSPDIAQ GVDTAHETRV EGAADPLDAQ GAGDQGLMFG YAIKDTPEMM PLPIALAHRL SRRLTEVRKS GVLPYLRPDG KTQVTIEYED DVPVRLDTVV VSTQHAADID LENTLTPDIR EKVLNTVLDD LAHDTLDTSS TRLLVNPTGK FVVGGPMGDA GLTGRKIIVD TYGGWARHGG GAFSGKDPSK VDRSAAYAMR WVAKNIVAAG LAERVEVQVA YAIGKAAPVG LFVETFGTAT VDPVKIEKIV PEVFDLRPGA IIRDLDLLRP IYAQTAAYGH FGRTDVELPW EQLNKVDELK RAV

NT Sequence
GTGAGCGAAA AGGGTCGCCT GTTTACCAGT GAGTCGGTGA CGGAGGGACA TCCCGACAAG ATCTGTGACG CGATCAGCGA CTCGGTGCTC GACGCGCTGC TGGCGCAGGA CCCCCGCTCA CGTGTCGCGG TCGAGACCCT GGTCACCACC GGGCAGGTGC ACGTGGTCGG CGAGGTGACG ACGACGGCCA AGGAGGCGTT CGCCGACATC ACCAACACGG TGCGCGAGCG CATCCTCGAC ATCGGCTACG ACTCCTCGGA CAAGGGCTTC GACGGCGCCT CCTGCGGGGT GAACATCGGC ATCGGCGCGC AGTCACCCGA CATCGCCCAG GGCGTTGACA CCGCCCACGA GACCCGCGTC GAGGGCGCGG CCGACCCGCT GGACGCCCAG GGCGCCGGCG ACCAGGGCCT GATGTTCGGC TACGCCATCA AGGACACCCC GGAGATGATG CCGCTGCCGA TCGCGCTGGC GCACCGGCTG TCGCGGCGGC TGACCGAGGT CCGCAAGAGC GGCGTGCTGC CCTACCTGCG TCCGGACGGC AAGACGCAGG TCACCATCGA ATACGAGGAC GACGTTCCCG TCCGGCTGGA CACCGTGGTG GTGTCCACCC AGCACGCGGC CGACATCGAC CTGGAGAACA CCCTGACCCC CGACATCCGG GAAAAGGTGC TCAACACCGT GCTCGACGAC CTGGCGCACG ACACCCTGGA CACCTCCTCG ACGCGGTTGC TGGTCAACCC GACCGGCAAG TTCGTCGTCG GCGGCCCGAT GGGCGACGCG GGGCTGACCG GCCGCAAGAT CATCGTCGAC ACCTACGGCG GCTGGGCCCG CCACGGCGGC GGCGCCTTCT CCGGCAAGGA TCCGTCGAAG GTGGACCGGT CCGCGGCGTA CGCGATGCGC TGGGTGGCCA AGAACATCGT CGCCGCCGGG CTGGCGGAGC GGGTGGAGGT GCAGGTGGCC TACGCCATCG GCAAGGCCGC CCCGGTGGGC CTGTTCGTGG AGACCTTCGG CACCGCGACC GTCGACCCGG TCAAGATCGA GAAGATCGTG CCCGAGGTGT TCGACCTGCG GCCCGGCGCG ATCATCCGCG ACCTGGACCT GCTGCGCCCG ATCTACGCGC AGACCGCCGC CTACGGGCAC TTCGGCCGCA CCGACGTCGA ACTGCCCTGG GAGCAGCTGA ACAAGGTCGA CGAGCTCAAG CGCGCCGTC

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