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Seattle Structural Genomics Center for Infectious Disease

MysmA.00556.a: Succinyl-CoA ligase [ADP-forming] subunit alpha

Target Characteristics

from organism: Mycobacterium smegmatis ATCC 700084 / mc(2)155
most recent status: soluble
center reference id: MysmA.00556.a
is community request: False
associated disease:
NIH risk group: 2
is select agent: False
NIH priority
pathogens category:
IIIC

Ordering Clones & Proteins

If there are materials available for this target, they will be listed below. Materials can be ordered from SSGCID using the button in the "order material" column. Clicking the button will add the material to a virtual cart. You may order multiple materials at a time at no cost to you, as this contract is funded by NIAID. When you are ready to place your order, click the "Place Order" link which will appear in the top right corner of the page after you place your first item in your cart.

External Resources

Resource Reference ID
OrthoMCL: OG5_127106
PATRIC ID: fig|246196.19.peg.5384
RefSeq: YP_889761.1
UniProt: A0R3M3

Enzyme & Pathway Information

Pathway Pathway ID EC Number
superpathway of glycolysis, pyruvate dehydrogenase, TCA, and glyoxylate bypass GLYCOLYSIS-TCA-GLYOX-BYPASS 6.2.1.5
reductive TCA cycle I P23-PWY 6.2.1.5
incomplete reductive TCA cycle P42-PWY 6.2.1.5
reductive TCA cycle II PWY-5392 6.2.1.5
superpathway of cytosolic glycolysis (plants), pyruvate dehydrogenase and TCA cycle PWY-5464 6.2.1.5
pyruvate fermentation to acetate V PWY-5537 6.2.1.5
pyruvate fermentation to acetate VI PWY-5538 6.2.1.5
TCA cycle II (plants and fungi) PWY-5690 6.2.1.5
partial TCA cycle (obligate autotrophs) PWY-5913 6.2.1.5
Methanobacterium thermoautotrophicum biosynthetic metabolism PWY-6146 6.2.1.5
TCA cycle III (animals) PWY66-398 6.2.1.5
methylaspartate cycle PWY-6728 6.2.1.5
TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase) PWY-6969 6.2.1.5
anaerobic energy metabolism (invertebrates, mitochondrial) PWY-7384 6.2.1.5
superpathway of anaerobic energy metabolism (invertebrates) PWY-7389 6.2.1.5
TCA cycle I (prokaryotic) TCA 6.2.1.5
superpathway of glyoxylate bypass and TCA TCA-GLYOX-BYPASS 6.2.1.5

Sequences

These sequences are the native gene sequence; sequences of constructs derived from these sequences may differ due to codon optimization or other protocols. To find the specific sequence of any material you may have ordered, click on the "more" button next to the name of that material.
AA Sequence
MSIFLNKDSK VIVQGITGGE GTKHTALMLK AGTQIVGGVN ARKAGTTVSH KDKDGNDIEL PVFGSVAEAI KETGADVSIA FVPPAFSKDA IIEAIDAEIP LLVVITEGIP VQDTAYAWAY NVDKGQKTRI IGPNCPGIIT PGEALVGITP NNITGKGPIG LVSKSGTLTY QMMYELRDFG FSTAIGIGGD PVIGTTHIDA IEAFEKDPET KVIVMIGEIG GDAEERAADY IKANVTKPVV GYVAGFTAPE GKTMGHAGAI VSGSSGTAAA KKEALEAAGV KVGKTPSETA KLAREILQSL

NT Sequence
ATGTCGATCT TTCTGAACAA GGACTCCAAG GTCATCGTCC AGGGCATCAC CGGTGGTGAG GGAACCAAGC ACACCGCGCT GATGCTCAAG GCCGGCACCC AGATCGTCGG TGGCGTGAAC GCGCGCAAGG CCGGCACCAC CGTGTCCCAC AAGGACAAGG ACGGCAACGA CATCGAACTC CCGGTGTTCG GCAGTGTCGC CGAGGCCATC AAGGAGACCG GCGCCGACGT GTCGATCGCC TTTGTGCCGC CGGCCTTCTC GAAGGACGCC ATCATCGAGG CCATCGACGC CGAGATCCCG CTGCTGGTGG TCATCACCGA GGGCATCCCG GTGCAGGACA CCGCCTACGC GTGGGCCTAC AACGTCGACA AGGGTCAGAA GACCCGCATC ATCGGCCCCA ACTGCCCCGG CATCATCACC CCCGGTGAGG CGCTGGTCGG CATCACGCCG AACAACATCA CCGGCAAGGG CCCGATCGGT CTGGTGTCGA AGTCCGGCAC GCTGACCTAC CAGATGATGT ACGAGCTGCG CGATTTCGGT TTCTCGACCG CCATCGGCAT CGGCGGCGAC CCGGTCATCG GCACCACCCA CATCGACGCC ATCGAGGCGT TCGAGAAGGA CCCCGAGACC AAGGTCATCG TGATGATCGG CGAGATCGGC GGCGACGCCG AGGAGCGCGC GGCCGACTAC ATCAAGGCCA ACGTCACCAA GCCGGTCGTC GGCTACGTCG CGGGCTTCAC CGCCCCGGAG GGCAAGACCA TGGGCCACGC CGGCGCCATC GTGTCGGGTT CGTCGGGCAC CGCCGCGGCC AAGAAGGAGG CCCTTGAGGC CGCGGGCGTC AAGGTCGGCA AGACCCCGTC CGAGACCGCC AAGCTGGCCC GCGAGATCCT GCAGTCGCTG

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