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MysmA.00640.a: Acetate kinase

Target Characteristics

from organism: Mycobacterium smegmatis ATCC 700084 / mc(2)155
most recent status: in PDB
center reference id: MysmA.00640.a
is community request: False
associated disease:
NIH risk group: 2
is select agent: False
NIH priority
pathogens category:
IIIC

Ordering Clones & Proteins

If there are materials available for this target, they will be listed below. Materials can be ordered from SSGCID using the button in the "order material" column. Clicking the button will add the material to a virtual cart. You may order multiple materials at a time at no cost to you, as this contract is funded by NIAID. When you are ready to place your order, click the "Place Order" link which will appear in the top right corner of the page after you place your first item in your cart.

Proteins

CENTER
REFERENCE ID
DOMAIN/REGION
DESCRIPTION
INFO AA
START
AA
STOP
ORDER
MATERIAL
MysmA.00640.a.A1.PS00601 Full length( MysmA.00640.a ) 1 376

Structures

image of structure for 4IJN
4IJN
Deposited: 12/21/2012
Determination: XRay
Diffraction Image
Clone: MysmA.00640.a.A1.GE28816
Protein: MysmA.00640.a.A1.PS00601

Publications by SSGCID

Increasing the structural coverage of tuberculosis drug targets.
Abendroth J, Abramov A, Armour B, Barrett LK, Baugh L, Begley DW, Buchko GW, Choi R, Clifton MC, Dieterich SH, Dranow DM, Edwards TE, Fairman JW, Ferrell M, Fox D, Gardberg AS, Hewitt SN, Lorimer D, Lyons-Abbott S, Mundt E, Muruthi MM, Myers J, Myler PJ, Napuli AJ, Phan I, Sekar A, Serbzhinskiy D, Stacy R, Staker BL, Stewart LJ, Taylor BM, Thompkins K, Tran N, Van Voorhis WC, Zhang Y
Tuberculosis (Edinb) - 2014
volume 95, issue 2, pages 142-8
PMID: 25613812; PMCID: PMC4361283
PDB: 3GVC, 3GVG, 3GWC, 3H7F, 3H81, 3HE2, 3HWI, 3HWK, 3HZG, 3ICO, 3KHP, 3LLS, 3MOY, 3MPZ, 3MYB, 3NDN, 3NDO, 3NF4, 3NG3, 3NJD, 3NWO, 3O0M, 3O38, 3OC6, 3OC7, 3OEC, 3OI9, 3OKS, 3OL3, 3OL4, 3OME, 3P0T, 3P2Y, 3P4I, 3P4T, 3P5M, 3P85, 3PE8, 3PGX, 3PK0, 3PPI, 3PXX, 3PZY, 3Q1T, 3Q8N, 3QBP, 3QDF, 3QH4, 3QHA, 3QIV, 3QK8, 3QKA, 3QLJ, 3QMJ, 3QRE, 3QUA, 3QUV, 3QXI, 3QXZ, 3QYR, 3R0O, 3R1I, 3R1J, 3R20, 3R2N, 3R4T, 3R6H, 3R6O, 3R7K, 3R8C, 3R9P, 3R9Q, 3R9R, 3R9S, 3R9T, 3RD5, 3RD7, 3RD8, 3RFQ, 3RIH, 3RR2, 3RR6, 3RRP, 3RRV, 3RSI, 3RV2, 3S55, 3S82, 3SBX, 3SF6, 3SLL, 3SVK, 3SVT, 3SWO, 3SWT, 3SWX, 3SX2, 3T3W, 3T7C, 3TAV, 3TCR, 3TDE, 3TJR, 3TL3, 3TLF, 3TRR, 3TSC, 3TX2, 3TZQ, 3TZU, 3U0A, 3U0B, 3UCX, 3UVE, 4DI1, 4DIE, 4DQ8, 4DXL, 4ED4, 4EGE, 4EGF, 4EMD, 4EO9, 4EYE, 4F3W, 4F47, 4FFC, 4GK6, 4HDT, 4HR3, 4I1Y, 4IJN, 4IV6, 4IZ9, 4J5I, 4KAM, 4LGV, 4O2D, 5EJ2

Citations by Others

Investigation of pyrophosphate versus ATP substrate selection in the Entamoeba histolytica acetate kinase
T Dang, C Ingram-Smith- Scientific Reports, 2017 - ncbi.nlm.nih.gov
PDB: 4IJN

This list was obtained from Google Scholar searches using the Open Source tool https://github.com/ckreibich/scholar.py and each citation has been manually reviewed.

External Resources

Resource Reference ID
OrthoMCL: OG5_130287
PATRIC ID: fig|246196.19.peg.779
RefSeq: YP_885189.1
UniProt: A0QQK1

Enzyme & Pathway Information

Pathway Pathway ID EC Number
(S)-propane-1,2-diol degradation PWY-7013 2.7.2.1
superpathway of L-threonine metabolism THREOCAT-PWY 2.7.2.1

Sequences

These sequences are the native gene sequence; sequences of constructs derived from these sequences may differ due to codon optimization or other protocols. To find the specific sequence of any material you may have ordered, click on the "more" button next to the name of that material.
AA Sequence
MTVLVVNSGS SSLKYAVVRP ASGEFLADGI IEEIGSGAVP DHDAALRAAF DELAAAGLHL EDLDLKAVGH RMVHGGKTFY KPSVVDDELI AKARELSPLA PLHNPPAIKG IEVARKLLPD LPHIAVFDTA FFHDLPAPAS TYAIDRELAE TWHIKRYGFH GTSHEYVSQQ AAIFLDRPLE SLNQIVLHLG NGASASAVAG GKAVDTSMGL TPMEGLVMGT RSGDIDPGVI MYLWRTAGMS VDDIESMLNR RSGVLGLGGA SDFRKLRELI ESGDEHAKLA YDVYIHRLRK YIGAYMAVLG RTDVISFTAG VGENVPPVRR DALAGLGGLG IEIDDALNSA KSDEPRLIST PDSRVTVLVV PTNEELAIAR ACVGVV

NT Sequence
GTGACAGTAC TCGTCGTCAA CTCAGGGTCG TCGTCGCTGA AATACGCCGT GGTGCGGCCG GCCAGCGGGG AATTCCTGGC CGACGGCATC ATCGAGGAGA TCGGGTCGGG CGCGGTGCCC GACCATGACG CCGCGTTGCG CGCCGCGTTC GACGAACTCG CCGCCGCGGG TCTCCATCTG GAAGACCTCG ATCTGAAGGC CGTCGGGCAC CGGATGGTCC ACGGCGGCAA GACGTTCTAC AAGCCGTCGG TGGTCGACGA CGAGCTCATC GCCAAGGCGC GCGAGCTCTC CCCGCTGGCG CCGCTGCACA ACCCGCCCGC CATCAAGGGC ATCGAGGTCG CCCGCAAGCT GCTGCCGGAC CTGCCGCACA TCGCCGTGTT CGACACCGCG TTCTTCCACG ACCTGCCCGC GCCCGCGAGC ACCTACGCCA TCGACCGCGA ACTCGCCGAG ACGTGGCACA TCAAGCGCTA CGGTTTTCAT GGCACGTCGC ACGAGTACGT CAGCCAGCAG GCCGCGATCT TCCTCGACCG TCCGCTGGAA TCGCTGAATC AGATTGTGCT GCACCTGGGT AACGGTGCCT CGGCAAGCGC CGTGGCAGGT GGTAAGGCCG TCGACACGTC GATGGGTCTG ACCCCGATGG AGGGCCTGGT GATGGGCACG CGCAGCGGTG ACATCGACCC CGGGGTCATC ATGTACCTGT GGCGCACCGC GGGCATGAGC GTCGACGACA TCGAGTCGAT GCTCAACCGG CGCTCCGGGG TCCTCGGTCT CGGTGGCGCC AGCGACTTCC GCAAGCTTCG TGAGCTCATC GAATCCGGGG ATGAGCACGC GAAACTGGCG TACGACGTCT ACATCCACCG ACTGCGCAAG TACATCGGCG CGTACATGGC CGTGCTCGGC AGGACCGACG TGATCAGCTT CACCGCCGGG GTGGGCGAGA ACGTCCCCCC GGTGCGGCGC GATGCGTTGG CCGGGCTGGG CGGTCTGGGC ATCGAGATCG ATGATGCGCT GAACTCCGCG AAATCCGATG AGCCCCGGCT CATCTCGACC CCGGATTCGC GTGTGACCGT GCTCGTGGTG CCCACCAACG AGGAACTCGC GATCGCCCGT GCGTGTGTGG GCGTGGTG

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