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Seattle Structural Genomics Center for Infectious Disease

MysmA.00754.a: HIT family protein

Target Characteristics

from organism: Mycobacterium smegmatis ATCC 700084 / mc(2)155
most recent status: in PDB
center reference id: MysmA.00754.a
is community request: False
associated disease:
NIH risk group: 2
is select agent: False
NIH priority
pathogens category:
IIIC

Ordering Clones & Proteins

If there are materials available for this target, they will be listed below. Materials can be ordered from SSGCID using the button in the "order material" column. Clicking the button will add the material to a virtual cart. You may order multiple materials at a time at no cost to you, as this contract is funded by NIAID. When you are ready to place your order, click the "Place Order" link which will appear in the top right corner of the page after you place your first item in your cart.

Clones*

CENTER
REFERENCE ID
DOMAIN/REGION
DESCRIPTION
INFO AA
START
AA
STOP
ORDER
MATERIAL
MysmA.00754.a.A1.GE28835 Full length( MysmA.00754.a ) 1 145 GE28835
* SSGCID clones represent un-induced expression constructs which have been verified by sequencing from vector primers. Clones may contain a tag, such as N-term 6xHis. Get sequence information using the button in the "info" column.

Proteins

CENTER
REFERENCE ID
DOMAIN/REGION
DESCRIPTION
INFO AA
START
AA
STOP
ORDER
MATERIAL
MysmA.00754.a.A1.PS00611 Full length( MysmA.00754.a ) 1 145

Structures

image of structure for 3O0M
3O0M
Deposited: 7/19/2010
Determination: XRay
Diffraction Image
Clone: MysmA.00754.a.A1.GE28835
Protein: MysmA.00754.a.A1.PS00611

Publications by SSGCID

Increasing the structural coverage of tuberculosis drug targets.
Abendroth J, Abramov A, Armour B, Barrett LK, Baugh L, Begley DW, Buchko GW, Choi R, Clifton MC, Dieterich SH, Dranow DM, Edwards TE, Fairman JW, Ferrell M, Fox D, Gardberg AS, Hewitt SN, Lorimer D, Lyons-Abbott S, Mundt E, Muruthi MM, Myers J, Myler PJ, Napuli AJ, Phan I, Sekar A, Serbzhinskiy D, Stacy R, Staker BL, Stewart LJ, Taylor BM, Thompkins K, Tran N, Van Voorhis WC, Zhang Y
Tuberculosis (Edinb) - 2014
volume 95, issue 2, pages 142-8
PMID: 25613812; PMCID: PMC4361283
PDB: 3GVC, 3GVG, 3GWC, 3H7F, 3H81, 3HE2, 3HWI, 3HWK, 3HZG, 3ICO, 3KHP, 3LLS, 3MOY, 3MPZ, 3MYB, 3NDN, 3NDO, 3NF4, 3NG3, 3NJD, 3NWO, 3O0M, 3O38, 3OC6, 3OC7, 3OEC, 3OI9, 3OKS, 3OL3, 3OL4, 3OME, 3P0T, 3P2Y, 3P4I, 3P4T, 3P5M, 3P85, 3PE8, 3PGX, 3PK0, 3PPI, 3PXX, 3PZY, 3Q1T, 3Q8N, 3QBP, 3QDF, 3QH4, 3QHA, 3QIV, 3QK8, 3QKA, 3QLJ, 3QMJ, 3QRE, 3QUA, 3QUV, 3QXI, 3QXZ, 3QYR, 3R0O, 3R1I, 3R1J, 3R20, 3R2N, 3R4T, 3R6H, 3R6O, 3R7K, 3R8C, 3R9P, 3R9Q, 3R9R, 3R9S, 3R9T, 3RD5, 3RD7, 3RD8, 3RFQ, 3RIH, 3RR2, 3RR6, 3RRP, 3RRV, 3RSI, 3RV2, 3S55, 3S82, 3SBX, 3SF6, 3SLL, 3SVK, 3SVT, 3SWO, 3SWT, 3SWX, 3SX2, 3T3W, 3T7C, 3TAV, 3TCR, 3TDE, 3TJR, 3TL3, 3TLF, 3TRR, 3TSC, 3TX2, 3TZQ, 3TZU, 3U0A, 3U0B, 3UCX, 3UVE, 4DI1, 4DIE, 4DQ8, 4DXL, 4ED4, 4EGE, 4EGF, 4EMD, 4EO9, 4EYE, 4F3W, 4F47, 4FFC, 4GK6, 4HDT, 4HR3, 4I1Y, 4IJN, 4IV6, 4IZ9, 4J5I, 4KAM, 4LGV, 4O2D, 5EJ2

Citations by Others

Crystal Structure of Histidine Triad Nucleotide-Binding Protein from the Pathogenic Fungus Candida albicans
A Jung, JS Yun, S Kim, SR Kim, M Shin- Molecules and, 2019 - ncbi.nlm.nih.gov
PDB: 3O0M
Evolutionary coupling methods in de novo protein structure prediction
S Seemayer - 2016 - edoc.ub.uni-muenchen.de
PDB: 3O0M
Structural Biology for Drug Design: Applications in Two Systems
KM Maize - 2016 - search.proquest.com
PDB: 3O0M
Rare Sidechain Conformations in Proteins and DNA
BJ Hintze - 2015 - search.proquest.com
PDB: 3O0M
Structural characterization of human histidine triad nucleotide-binding protein 2, a member of the histidine triad superfamily
KM Maize, CR Wagner, BC Finzel - FEBS Journal, 2013 - Wiley Online Library
cited by: 4 others
PDB: 3O0M
Structural Insights into the Novel Diadenosine 5′,5‴-P1,P4-Tetraphosphate Phosphorylase from Mycobacterium tuberculosis H37Rv
S Mori, K Shibayama, JI Wachino, Y Arakawa - Journal of Molecular Biology, 2011 - Elsevier
cited by: 3 others
PDB: 3O0M

This list was obtained from Google Scholar searches using the Open Source tool https://github.com/ckreibich/scholar.py and each citation has been manually reviewed.

External Resources

Resource Reference ID
OrthoMCL: OG5_126794
PATRIC ID: fig|246196.19.peg.4904
RefSeq: YP_889279.1
UniProt: A0R291

Enzyme & Pathway Information

Pathway Pathway ID EC Number
3.6.1.17

Sequences

These sequences are the native gene sequence; sequences of constructs derived from these sequences may differ due to codon optimization or other protocols. To find the specific sequence of any material you may have ordered, click on the "more" button next to the name of that material.
AA Sequence
MSCVFCAIVS GDAPAIRIYE DENFLGILDI RPFTRGHTLV IPKTHTVDLT DTPPETVAGM AAVGQRIARA ARESGLHADG NNIAINDGKA AFQTVFHIHL HVVPRRNGDK LSFAKGMVMR RDPDREESGR LLRAALAQLD SAEQD

NT Sequence
ATGTCATGCG TGTTCTGTGC CATCGTCTCC GGTGACGCCC CAGCCATCCG CATCTACGAA GACGAGAACT TCCTGGGCAT CCTCGACATC CGGCCGTTCA CCCGCGGCCA CACGCTGGTG ATCCCGAAAA CCCACACCGT CGACCTCACG GACACGCCGC CGGAGACGGT CGCCGGTATG GCGGCCGTCG GCCAGCGCAT CGCGCGGGCC GCACGCGAAT CGGGACTGCA CGCCGACGGC AACAACATCG CGATCAACGA CGGCAAGGCC GCGTTCCAGA CGGTGTTCCA CATCCACCTG CACGTGGTGC CCCGTCGCAA CGGCGACAAG CTGTCGTTCG CCAAGGGCAT GGTGATGCGC CGCGACCCCG ACCGCGAGGA GTCCGGCAGG CTGCTGCGGG CGGCCCTGGC GCAACTGGAC AGCGCCGAGC AGGAT

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