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MysmA.00762.b: Short chain dehydrogenase

Target Characteristics

from organism: Mycobacterium smegmatis ATCC 700084 / mc(2)155
most recent status: in PDB
center reference id: MysmA.00762.b
is community request: False
associated disease:
NIH risk group: 2
is select agent: False
NIH priority
pathogens category:
IIIC

Ordering Clones & Proteins

If there are materials available for this target, they will be listed below. Materials can be ordered from SSGCID using the button in the "order material" column. Clicking the button will add the material to a virtual cart. You may order multiple materials at a time at no cost to you, as this contract is funded by NIAID. When you are ready to place your order, click the "Place Order" link which will appear in the top right corner of the page after you place your first item in your cart.

Clones*

CENTER
REFERENCE ID
DOMAIN/REGION
DESCRIPTION
INFO AA
START
AA
STOP
ORDER
MATERIAL
MysmA.00762.b.A1.GE28838 Full length( MysmA.00762.b ) 1 262 GE28838
* SSGCID clones represent un-induced expression constructs which have been verified by sequencing from vector primers. Clones may contain a tag, such as N-term 6xHis. Get sequence information using the button in the "info" column.

Proteins

CENTER
REFERENCE ID
DOMAIN/REGION
DESCRIPTION
INFO AA
START
AA
STOP
ORDER
MATERIAL
MysmA.00762.b.A1.PS00603 Full length( MysmA.00762.b ) 1 262

Structures

image of structure for 3O38
3O38
Deposited: 7/23/2010
Determination: XRay
Diffraction Image
Clone: MysmA.00762.b.A1.GE28838
Protein: MysmA.00762.b.A1.PS00603

Publications by SSGCID

Increasing the structural coverage of tuberculosis drug targets.
Abendroth J, Abramov A, Armour B, Barrett LK, Baugh L, Begley DW, Buchko GW, Choi R, Clifton MC, Dieterich SH, Dranow DM, Edwards TE, Fairman JW, Ferrell M, Fox D, Gardberg AS, Hewitt SN, Lorimer D, Lyons-Abbott S, Mundt E, Muruthi MM, Myers J, Myler PJ, Napuli AJ, Phan I, Sekar A, Serbzhinskiy D, Stacy R, Staker BL, Stewart LJ, Taylor BM, Thompkins K, Tran N, Van Voorhis WC, Zhang Y
Tuberculosis (Edinb) - 2014
volume 95, issue 2, pages 142-8
PMID: 25613812; PMCID: PMC4361283
PDB: 3GVC, 3GVG, 3GWC, 3H7F, 3H81, 3HE2, 3HWI, 3HWK, 3HZG, 3ICO, 3KHP, 3LLS, 3MOY, 3MPZ, 3MYB, 3NDN, 3NDO, 3NF4, 3NG3, 3NJD, 3NWO, 3O0M, 3O38, 3OC6, 3OC7, 3OEC, 3OI9, 3OKS, 3OL3, 3OL4, 3OME, 3P0T, 3P2Y, 3P4I, 3P4T, 3P5M, 3P85, 3PE8, 3PGX, 3PK0, 3PPI, 3PXX, 3PZY, 3Q1T, 3Q8N, 3QBP, 3QDF, 3QH4, 3QHA, 3QIV, 3QK8, 3QKA, 3QLJ, 3QMJ, 3QRE, 3QUA, 3QUV, 3QXI, 3QXZ, 3QYR, 3R0O, 3R1I, 3R1J, 3R20, 3R2N, 3R4T, 3R6H, 3R6O, 3R7K, 3R8C, 3R9P, 3R9Q, 3R9R, 3R9S, 3R9T, 3RD5, 3RD7, 3RD8, 3RFQ, 3RIH, 3RR2, 3RR6, 3RRP, 3RRV, 3RSI, 3RV2, 3S55, 3S82, 3SBX, 3SF6, 3SLL, 3SVK, 3SVT, 3SWO, 3SWT, 3SWX, 3SX2, 3T3W, 3T7C, 3TAV, 3TCR, 3TDE, 3TJR, 3TL3, 3TLF, 3TRR, 3TSC, 3TX2, 3TZQ, 3TZU, 3U0A, 3U0B, 3UCX, 3UVE, 4DI1, 4DIE, 4DQ8, 4DXL, 4ED4, 4EGE, 4EGF, 4EMD, 4EO9, 4EYE, 4F3W, 4F47, 4FFC, 4GK6, 4HDT, 4HR3, 4I1Y, 4IJN, 4IV6, 4IZ9, 4J5I, 4KAM, 4LGV, 4O2D, 5EJ2

Citations by Others

Rare Sidechain Conformations in Proteins and DNA
BJ Hintze - 2015 - search.proquest.com
PDB: 3O38

This list was obtained from Google Scholar searches using the Open Source tool https://github.com/ckreibich/scholar.py and each citation has been manually reviewed.

External Resources

Resource Reference ID
OrthoMCL: OG5_168406
PATRIC ID: fig|246196.19.peg.5847
RefSeq: YP_890236.1
UniProt: A0R4Z8

Enzyme & Pathway Information

Pathway Pathway ID EC Number
biotin biosynthesis I BIOTIN-BIOSYNTHESIS-PWY 1.1.1.100
(5Z)-dodecenoate biosynthesis I PWY0-862 1.1.1.100
superpathway of fatty acid biosynthesis I (E. coli) PWY0-881 1.1.1.100
arachidonate biosynthesis PWY-5353 1.1.1.100
petroselinate biosynthesis PWY-5367 1.1.1.100
cis-vaccenate biosynthesis PWY-5973 1.1.1.100
superpathway of mycolate biosynthesis PWY-6113 1.1.1.100
palmitoleate biosynthesis I (from (5Z)-dodec-5-enoate) PWY-6282 1.1.1.100
superpathway of unsaturated fatty acids biosynthesis (E. coli) PWY-6284 1.1.1.100
superpathway of fatty acids biosynthesis (E. coli) PWY-6285 1.1.1.100
8-amino-7-oxononanoate biosynthesis I PWY-6519 1.1.1.100
eicosapentaenoate biosynthesis from arachidonate PWY-6940 1.1.1.100
docosahexanoate biosynthesis II PWY-6951 1.1.1.100
docosahexanoate biosynthesis I PWY-7053 1.1.1.100
gondoate biosynthesis (anaerobic) PWY-7663 1.1.1.100
oleate biosynthesis IV (anaerobic) PWY-7664 1.1.1.100
(5Z)-dodecenoate biosynthesis II PWY-7858 1.1.1.100
mycolate biosynthesis PWYG-321 1.1.1.100

Sequences

These sequences are the native gene sequence; sequences of constructs derived from these sequences may differ due to codon optimization or other protocols. To find the specific sequence of any material you may have ordered, click on the "more" button next to the name of that material.
AA Sequence
MNLSEAPKEI DGHGLLKGKV VLVTAAAGTG IGSTTARRAL LEGADVVISD YHERRLGETR DQLADLGLGR VEAVVCDVTS TEAVDALITQ TVEKAGRLDV LVNNAGLGGQ TPVVDMTDEE WDRVLNVTLT SVMRATRAAL RYFRGVDHGG VIVNNASVLG WRAQHSQSHY AAAKAGVMAL TRCSAIEAVE FGVRINAVSP SIARHKFLEK TSSSELLDRL ASDEAFGRAA EPWEVAATIA FLASDYSSYM TGEVVSVSSQ RA

NT Sequence
ATGAATCTGT CGGAGGCCCC GAAAGAGATT GACGGGCACG GTCTTCTGAA GGGCAAGGTG GTCCTGGTGA CCGCCGCCGC CGGTACCGGC ATCGGCTCGA CCACCGCGCG GCGTGCGCTG CTCGAGGGTG CCGACGTGGT GATCTCCGAC TACCACGAGC GCAGGCTGGG GGAGACCCGC GATCAGCTGG CCGACCTGGG CCTGGGACGT GTCGAAGCCG TCGTGTGTGA CGTGACCTCC ACCGAGGCCG TCGATGCGCT GATCACCCAG ACCGTCGAGA AGGCCGGACG GCTGGATGTG CTGGTCAACA ACGCCGGCCT GGGCGGGCAG ACACCCGTCG TCGACATGAC AGACGAGGAG TGGGACCGCG TCCTCAACGT CACGCTCACC TCGGTCATGC GCGCCACGCG GGCCGCGTTG CGGTACTTCC GCGGCGTCGA CCACGGCGGT GTCATCGTCA ACAACGCGAG CGTGCTGGGT TGGCGCGCAC AGCATTCGCA GTCGCACTAC GCGGCCGCGA AAGCCGGTGT CATGGCCCTG ACGCGCTGCA GCGCGATCGA GGCCGTCGAG TTCGGCGTGC GCATCAACGC CGTGTCGCCG AGCATCGCGC GGCACAAGTT CCTGGAGAAG ACGTCGTCCT CGGAACTGCT GGACCGCCTG GCCAGTGACG AGGCGTTCGG CCGCGCGGCC GAACCGTGGG AAGTCGCGGC GACCATCGCC TTCCTCGCGA GTGACTACTC CAGTTACATG ACCGGAGAGG TCGTCTCGGT GTCCAGCCAG CGGGCC

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