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Seattle Structural Genomics Center for Infectious Disease

MysmA.01625.a: S-adenosylmethionine synthetase

Target Characteristics

from organism: Mycobacterium smegmatis ATCC 700084 / mc(2)155
most recent status: crystallized
center reference id: MysmA.01625.a
is community request: False
associated disease:
NIH risk group: 2
is select agent: False
NIH priority
pathogens category:
IIIC

Ordering Clones & Proteins

If there are materials available for this target, they will be listed below. Materials can be ordered from SSGCID using the button in the "order material" column. Clicking the button will add the material to a virtual cart. You may order multiple materials at a time at no cost to you, as this contract is funded by NIAID. When you are ready to place your order, click the "Place Order" link which will appear in the top right corner of the page after you place your first item in your cart.

Proteins

CENTER
REFERENCE ID
DOMAIN/REGION
DESCRIPTION
INFO AA
START
AA
STOP
ORDER
MATERIAL
MysmA.01625.a.A1.PW28876 Full length( MysmA.01625.a ) 1 399

External Resources

Resource Reference ID
OrthoMCL: OG5_126734
PATRIC ID: fig|246196.19.peg.3016
RefSeq: YP_887371.1
UniProt: A0QWT3

Enzyme & Pathway Information

Pathway Pathway ID EC Number
ethylene biosynthesis I (plants) ETHYL-PWY 2.5.1.6
L-methionine degradation I (to L-homocysteine) METHIONINE-DEG1-PWY 2.5.1.6
superpathway of S-adenosyl-L-methionine biosynthesis MET-SAM-PWY 2.5.1.6
aspartate superpathway PWY0-781 2.5.1.6
S-adenosyl-L-methionine cycle II PWY-5041 2.5.1.6
superpathway of L-methionine salvage and degradation PWY-5328 2.5.1.6
2'-deoxymugineic acid phytosiderophore biosynthesis PWY-5912 2.5.1.6
S-adenosyl-L-methionine cycle I PWY-6151 2.5.1.6
superpathway of L-cysteine biosynthesis (mammalian) PWY-6292 2.5.1.6
L-methionine salvage cycle II (plants) PWY-7270 2.5.1.6
L-methionine salvage cycle III PWY-7527 2.5.1.6
L-methionine salvage cycle I (bacteria and plants) PWY-7528 2.5.1.6
L-cysteine biosynthesis VI (from L-methionine) PWY-I9 2.5.1.6
S-adenosyl-L-methionine biosynthesis SAM-PWY 2.5.1.6

Sequences

These sequences are the native gene sequence; sequences of constructs derived from these sequences may differ due to codon optimization or other protocols. To find the specific sequence of any material you may have ordered, click on the "more" button next to the name of that material.
AA Sequence
MSKGRLFTSE SVTEGHPDKI CDAISDSVLD ALLEQDPKSR VAVETLVTTG QVHVAGEVTT TAYADIPKIV RDRILDIGYD SSTKGFDGAS CGVNVAIGAQ SPDIAQGVDT AHETRVEGKA DPLDLQGAGD QGLMFGYAIG DTPELMPLPI ALAHRLARRL TEVRKNGVLD YLRPDGKTQV TIQYDGTTPV RLDTVVLSTQ HADGIDLEGT LTPDIREKVV NTVLADLGHE TLDTSDYRLL VNPTGKFVLG GPMGDAGLTG RKIIVDTYGG WARHGGGAFS GKDPSKVDRS AAYAMRWVAK NVVAAGLAER VEVQVAYAIG KAAPVGLFVE TFGSETVDPA KIEKAIGEVF DLRPAAIVRD LDLLRPIYAP TAAYGHFGRT DIELPWEQTN KVDDLKSAI

NT Sequence
GTGAGCAAAG GTCGCCTGTT TACCAGTGAG TCGGTAACCG AAGGGCACCC CGACAAGATC TGTGACGCAA TCAGCGACTC TGTGCTCGAC GCGCTGCTGG AGCAGGATCC CAAGTCCCGC GTCGCCGTCG AGACGCTGGT CACCACGGGC CAGGTGCACG TCGCCGGTGA GGTGACCACC ACGGCGTACG CCGACATCCC CAAGATCGTG CGCGACCGCA TCCTCGACAT CGGCTACGAC TCGTCGACCA AGGGCTTCGA CGGCGCCTCG TGCGGCGTCA ACGTGGCGAT CGGTGCGCAG TCGCCCGACA TCGCCCAAGG CGTCGACACC GCCCACGAGA CCCGCGTCGA GGGCAAGGCC GACCCGCTGG ACCTGCAGGG CGCAGGCGAC CAGGGCCTGA TGTTCGGCTA CGCCATCGGC GACACCCCCG AACTCATGCC GCTGCCCATC GCGCTGGCCC ACCGCCTCGC GCGCCGCCTG ACCGAGGTGC GCAAGAACGG TGTGCTGGAC TACCTGCGGC CCGACGGCAA GACCCAGGTC ACCATCCAGT ACGACGGCAC CACCCCGGTG CGGTTGGACA CCGTGGTGCT GTCCACCCAG CACGCCGACG GCATCGACCT GGAGGGCACC CTCACGCCCG ACATCCGCGA GAAGGTCGTC AACACCGTGC TCGCCGATCT CGGCCATGAG ACCCTCGACA CGTCCGACTA CCGCCTGCTG GTCAACCCGA CGGGCAAGTT CGTCCTCGGC GGCCCCATGG GCGACGCCGG CCTGACCGGC CGCAAGATCA TCGTCGACAC CTACGGCGGC TGGGCTCGCC ACGGCGGCGG CGCCTTCTCG GGCAAGGATC CGTCAAAGGT CGACCGCTCG GCCGCCTACG CGATGCGCTG GGTCGCCAAG AACGTCGTCG CCGCTGGCCT GGCCGAGCGC GTCGAGGTGC AGGTCGCCTA CGCGATCGGC AAGGCCGCCC CGGTGGGTCT GTTCGTGGAG ACCTTCGGCA GCGAGACCGT CGACCCGGCC AAGATCGAGA AGGCCATCGG CGAGGTGTTC GACCTGCGTC CCGCCGCGAT CGTGCGCGAC CTCGACCTGC TGCGCCCGAT CTACGCGCCC ACCGCCGCGT ACGGACACTT CGGCCGCACC GACATCGAGC TGCCGTGGGA GCAGACCAAC AAGGTGGACG ACCTGAAGTC CGCCATC

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