NIAID Emerging and Re-emerging Infectious Diseases NIAID Bioinformatics Resource Centers NIAID Structural Genomic Centers Center for Structural Genomics of Infectious Disease
Seattle Structural Genomics Center for Infectious Disease

MytuD.00145.a: aspartyl-tRNA synthetase

Target Characteristics

from organism: Mycobacterium tuberculosis H37Rv
most recent status: purified
center reference id: MytuD.00145.a
is community request: True
associated disease: Tuberculosis
NIH risk group: 2
is select agent: False
NIH priority
pathogens category:
IIIC

Ordering Clones & Proteins

If there are materials available for this target, they will be listed below. Materials can be ordered from SSGCID using the button in the "order material" column. Clicking the button will add the material to a virtual cart. You may order multiple materials at a time at no cost to you, as this contract is funded by NIAID. When you are ready to place your order, click the "Place Order" link which will appear in the top right corner of the page after you place your first item in your cart.

Clones*

CENTER
REFERENCE ID
DOMAIN/REGION
DESCRIPTION
INFO AA
START
AA
STOP
ORDER
MATERIAL
MytuD.00145.a.A1.GE25249 Full length( MytuD.00145.a ) 1 596 GE25249
* SSGCID clones represent un-induced expression constructs which have been verified by sequencing from vector primers. Clones may contain a tag, such as N-term 6xHis. Get sequence information using the button in the "info" column.

Proteins

CENTER
REFERENCE ID
DOMAIN/REGION
DESCRIPTION
INFO AA
START
AA
STOP
ORDER
MATERIAL
MytuD.00145.a.A1.PW27581 Full length( MytuD.00145.a ) 1 596

External Resources

Resource Reference ID
OrthoMCL: OG5_127662
PATRIC ID: fig|83332.12.peg.2880
RefSeq: NP_217088.1
TubercuList: Rv2572c
MTB Network Portal: Rv2572c
UniProt: P9WFW3

Orthologues for Rv2572c

Species % Identity % Coverage Clones Proteins Structures
bovis 99 99 0 0 0
marinum 90 100 1 0 0
ulcerans 89 100 0 0 0
avium 88 99 0 0 0
leprae 88 99 1 0 0
paratuberculosis 88 99 0 0 0
smegmatis 82 99 1 0 1
abscessus 81 100 0 0 0

Enzyme & Pathway Information

Pathway Pathway ID EC Number
tRNA charging TRNA-CHARGING-PWY 6.1.1.12
L-asparagine biosynthesis III (tRNA-dependent) PWY490-4 6.1.1.23

Sequences

These sequences are the native gene sequence; sequences of constructs derived from these sequences may differ due to codon optimization or other protocols. To find the specific sequence of any material you may have ordered, click on the "more" button next to the name of that material.
AA Sequence
MFVLRSHAAG LLREGDAGQQ VTLAGWVARR RDHGGVIFID LRDASGIAQV VFRDPQDTEV LAQAHRLRAE FCVSVAGVVE IRPEGNANPE IATGEIEVNA TSLTVLGECA PLPFQLDEPA GEELRLKYRY LDLRRDDPAA AIRLRSRVNA AARAVLARHD FVEIETPTIT RSTPEGARDF LVPARLHPGS FYALPQSPQL FKQLLMVAGM ERYYQIARCY RDEDFRADRQ PEFTQLDMEM SFVDAEDIIA ISEEVLTELW ALIGYRIPTP IPRIGYAEAM RRFGTDKPDL RFGLELVECT DFFSDTTFRV FQAPYVGAVV MPGGASQPRR TLDGWQDWAK QRGHRGLAYV LVAEDGTLGG PVAKNLTEAE RTGLADHVGA KPGDCIFFSA GPVKSSRALL GAARVEIANR LGLIDPDAWA FVWVVDPPLF EPADEATAAG EVAVGSGAWT AVHHAFTAPK PEWEDRIESD TGSVLADAYD IVCNGHEIGG GSVRIHRRDI QERVFAVMGL DKAEAEEKFG FLLEAFMFGA PPHGGIAFGW DRTTALLAGM DSIREVIAFP KTGGGVDPLT DAPAPITAQQ RKESGIDAQP KRVQQA

NT Sequence
GTGTTTGTGC TGCGCAGCCA CGCCGCGGGT TTGCTACGGG AAGGCGACGC CGGGCAGCAG GTGACATTGG CCGGCTGGGT GGCTCGCCGC CGCGACCACG GCGGCGTGAT CTTCATCGAT CTGCGGGACG CTTCGGGCAT CGCACAGGTG GTGTTCCGCG ACCCCCAGGA CACTGAGGTG CTGGCGCAGG CTCACCGGCT GCGTGCGGAA TTCTGCGTAT CGGTGGCCGG CGTCGTCGAG ATCCGCCCGG AAGGCAACGC CAACCCGGAG ATCGCCACCG GCGAGATCGA GGTCAACGCC ACGTCGTTGA CCGTGCTGGG CGAATGTGCG CCGCTGCCGT TTCAGCTGGA CGAACCGGCG GGTGAGGAGT TGCGACTGAA GTACCGCTAC CTCGATCTGC GCCGCGACGA CCCCGCTGCG GCGATTCGAC TGCGTTCCCG GGTGAATGCC GCTGCGCGCG CGGTGCTGGC GCGTCACGAC TTCGTCGAGA TCGAGACGCC GACGATCACC CGCTCGACCC CGGAGGGAGC GCGCGACTTC CTGGTGCCGG CCCGACTGCA CCCCGGTTCG TTTTACGCCC TACCGCAGAG CCCGCAGCTG TTCAAGCAGC TGCTGATGGT GGCGGGGATG GAACGCTACT ACCAGATCGC CCGCTGCTAC CGCGACGAGG ACTTCCGCGC CGACCGCCAG CCCGAATTCA CCCAGCTCGA TATGGAGATG AGCTTCGTCG ACGCCGAGGA CATCATCGCG ATCTCCGAGG AAGTTCTGAC CGAGCTGTGG GCGCTGATAG GCTACCGGAT TCCGACGCCC ATCCCGCGGA TCGGCTATGC CGAAGCGATG CGCCGATTCG GTACGGACAA ACCCGACCTG CGGTTCGGGC TGGAGCTCGT CGAATGCACG GATTTCTTCT CCGACACCAC ATTTCGTGTC TTCCAGGCAC CGTATGTGGG CGCGGTGGTG ATGCCTGGCG GGGCGTCGCA GCCGCGGCGC ACGCTGGACG GCTGGCAGGA CTGGGCCAAG CAGCGCGGCC ACCGCGGACT GGCCTACGTG CTGGTCGCCG AAGACGGCAC GCTGGGCGGT CCGGTGGCCA AAAACCTGAC CGAGGCCGAG CGCACCGGAC TGGCCGACCA TGTCGGGGCC AAACCCGGCG ATTGCATCTT CTTCTCGGCC GGTCCGGTCA AATCGTCGCG GGCACTGCTG GGCGCGGCCC GCGTCGAGAT CGCCAACCGG CTGGGCCTGA TTGACCCCGA TGCGTGGGCA TTCGTCTGGG TCGTTGACCC GCCGCTGTTC GAGCCGGCCG ACGAAGCGAC CGCCGCCGGT GAGGTCGCGG TCGGCTCGGG GGCCTGGACC GCGGTGCACC ATGCCTTCAC CGCGCCGAAA CCGGAATGGG AGGACCGCAT CGAATCCGAT ACCGGCAGCG TGCTGGCCGA CGCGTACGAC ATCGTCTGCA ACGGCCACGA GATCGGTGGC GGCTCGGTGC GTATCCACCG CCGTGATATC CAGGAACGGG TGTTCGCGGT GATGGGCCTG GACAAGGCCG AGGCGGAGGA AAAGTTCGGA TTCCTGTTGG AGGCGTTCAT GTTTGGCGCA CCGCCGCACG GCGGAATCGC GTTCGGGTGG GACCGGACCA CCGCGCTGCT GGCCGGGATG GACTCGATCC GTGAGGTGAT CGCGTTCCCG AAGACCGGCG GCGGCGTCGA TCCGCTCACC GACGCGCCGG CGCCCATTAC CGCTCAGCAA CGTAAGGAGT CCGGAATAGA TGCCCAGCCC AAGCGGGTCC AGCAGGCA

© 2019 Seattle Children's Research Institute. All rights reserved.