NIAID Emerging and Re-emerging Infectious Diseases NIAID Bioinformatics Resource Centers NIAID Structural Genomic Centers Center for Structural Genomics of Infectious Disease
Seattle Structural Genomics Center for Infectious Disease

MytuD.00554.a: PROBABLE SHORT-CHAIN TYPE DEHYDROGENASE/REDUCTASE

Target Characteristics

from organism: Mycobacterium tuberculosis H37Rv
most recent status: in PDB
center reference id: MytuD.00554.a
is community request: True
associated disease: Tuberculosis
NIH risk group: 2
is select agent: False
NIH priority
pathogens category:
IIIC

Ordering Clones & Proteins

If there are materials available for this target, they will be listed below. Materials can be ordered from SSGCID using the button in the "order material" column. Clicking the button will add the material to a virtual cart. You may order multiple materials at a time at no cost to you, as this contract is funded by NIAID. When you are ready to place your order, click the "Place Order" link which will appear in the top right corner of the page after you place your first item in your cart.

Clones*

CENTER
REFERENCE ID
DOMAIN/REGION
DESCRIPTION
INFO AA
START
AA
STOP
ORDER
MATERIAL
MytuD.00554.a.B1.GE42761 Full length( MytuD.00554.a ) 1 250 GE42761
MytuD.00554.a.B12.GE42762 Full length( MytuD.00554.a ) 1 250 GE42762
MytuD.00554.a.B13.GE42763 Full length( MytuD.00554.a ) 1 250 GE42763
MytuD.00554.a.B14.GE42764 Full length( MytuD.00554.a ) 1 250 GE42764
* SSGCID clones represent un-induced expression constructs which have been verified by sequencing from vector primers. Clones may contain a tag, such as N-term 6xHis. Get sequence information using the button in the "info" column.

Proteins

CENTER
REFERENCE ID
DOMAIN/REGION
DESCRIPTION
INFO AA
START
AA
STOP
ORDER
MATERIAL
MytuD.00554.a.B1.PW38579 Full length( MytuD.00554.a ) 1 250

Structures

image of structure for 6UJK
6UJK
Deposited: 10/3/2019
Determination: XRay
Diffraction Image
Clone: MytuD.00554.a.B1.GE42761
Protein: MytuD.00554.a.B1.PW38579

External Resources

Resource Reference ID
OrthoMCL: OG5_129031
PATRIC ID: fig|83332.12.peg.1282
RefSeq: NP_215660.1
TubercuList: Rv1144
MTB Network Portal: Rv1144
UniProt: P9WGQ7

Orthologues for Rv1144

Species % Identity % Coverage Clones Proteins Structures
marinum 87 100 0 0 0
ulcerans 87 100 1 1 1
paratuberculosis 81 100 1 0 0
smegmatis 80 100 1 0 0
thermoresistibile 79 93 1 0 0
marinum 49 100 0 0 0
smegmatis 49 98 0 0 0
avium 47 98 1 1 1
thermoresistibile 43 100 1 0 0

Sequences

These sequences are the native gene sequence; sequences of constructs derived from these sequences may differ due to codon optimization or other protocols. To find the specific sequence of any material you may have ordered, click on the "more" button next to the name of that material.
AA Sequence
MKTKDAVAVV TGGASGLGLA TTKRLLDAGA QVVVVDLRGD DVVGGLGDRA RFAQADVTDE AAVSNALELA DSLGPVRVVV NCAGTGNAIR VLSRDGVFPL AAFRKIVDIN LVGTFNVLRL GAERIAKTEP IGEERGVIIN TASVAAFDGQ IGQAAYSASK GGVVGMTLPI ARDLASKLIR VVTIAPGLFD TPLLASLPAE AKASLGQQVP HPSRLGNPDE YGALVLHIIE NPMLNGEVIR LDGAIRMAPR

NT Sequence
ATGAAGACCA AAGACGCCGT AGCCGTTGTC ACCGGTGGCG CCTCAGGCCT GGGTCTGGCC ACCACCAAGC GGCTATTGGA CGCTGGGGCA CAGGTGGTCG TCGTGGACCT CCGCGGCGAC GACGTGGTTG GCGGGCTCGG CGATCGCGCG CGTTTTGCGC AAGCCGACGT CACCGACGAA GCCGCCGTCA GCAACGCGCT AGAGCTGGCG GATTCGCTCG GCCCGGTGCG GGTCGTCGTC AACTGCGCCG GCACCGGCAA CGCGATTCGC GTACTGAGTC GCGACGGCGT GTTCCCGCTG GCCGCGTTCC GCAAGATCGT GGACATCAAC CTAGTCGGCA CCTTCAACGT GCTGCGACTG GGCGCCGAGC GGATCGCCAA GACCGAACCG ATTGGGGAAG AGCGCGGCGT CATCATTAAC ACCGCCTCGG TGGCGGCATT CGACGGTCAG ATCGGCCAGG CCGCCTACTC GGCGTCCAAG GGCGGCGTAG TTGGCATGAC CCTGCCGATC GCCCGCGATC TGGCCAGCAA GCTGATCCGG GTGGTCACCA TTGCGCCGGG TCTGTTCGAC ACCCCGCTGC TGGCTTCATT GCCGGCGGAG GCCAAGGCCT CACTGGGCCA ACAGGTGCCG CATCCCTCGC GGCTGGGCAA CCCCGACGAG TACGGGGCGC TAGTTCTGCA CATCATCGAA AACCCGATGC TTAACGGCGA GGTCATCCGT CTGGACGGCG CCATCCGCAT GGCGCCGCGC

© 2020 Seattle Children's Research Institute. All rights reserved.