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Seattle Structural Genomics Center for Infectious Disease

MytuD.00781.a: acetyl-CoA acetyltransferase

Target Characteristics

from organism: Mycobacterium tuberculosis H37Rv
most recent status: expressed
center reference id: MytuD.00781.a
is community request: False
associated disease: Tuberculosis
NIH risk group: 2
is select agent: False
NIH priority
pathogens category:
IIIC

Ordering Clones & Proteins

If there are materials available for this target, they will be listed below. Materials can be ordered from SSGCID using the button in the "order material" column. Clicking the button will add the material to a virtual cart. You may order multiple materials at a time at no cost to you, as this contract is funded by NIAID. When you are ready to place your order, click the "Place Order" link which will appear in the top right corner of the page after you place your first item in your cart.

Clones*

CENTER
REFERENCE ID
DOMAIN/REGION
DESCRIPTION
INFO AA
START
AA
STOP
ORDER
MATERIAL
MytuD.00781.a.B1.GE27169 Full length( MytuD.00781.a ) 1 405 GE27169
MytuD.00781.a.B1.GE27590 Full length( MytuD.00781.a ) 1 405 GE27590
* SSGCID clones represent un-induced expression constructs which have been verified by sequencing from vector primers. Clones may contain a tag, such as N-term 6xHis. Get sequence information using the button in the "info" column.

External Resources

Resource Reference ID
OrthoMCL: OG5_128333
PATRIC ID: fig|83332.12.peg.1200
RefSeq: NP_215590.1
TubercuList: Rv1074c
MTB Network Portal: Rv1074c
UniProt: O53422

Orthologues for Rv1074c

Species % Identity % Coverage Clones Proteins Structures
marinum 93 100 1 0 0
ulcerans 92 100 1 0 0
avium 91 100 1 0 0
paratuberculosis 91 68 1 0 0
smegmatis 84 100 1 1 0
thermoresistibile 84 97 1 0 0
abscessus 83 100 1 1 0
paratuberculosis 40 99 0 0 0
marinum 39 99 0 0 0
ulcerans 39 99 1 0 0
thermoresistibile 38 78 0 0 0
thermoresistibile 37 87 1 0 0

Enzyme & Pathway Information

Pathway Pathway ID EC Number
acetoacetate degradation (to acetyl CoA) ACETOACETATE-DEG-PWY 2.3.1.9

Sequences

These sequences are the native gene sequence; sequences of constructs derived from these sequences may differ due to codon optimization or other protocols. To find the specific sequence of any material you may have ordered, click on the "more" button next to the name of that material.
AA Sequence
MPEAVIVSTA RSPIGRAMKG SLVGMRPDDL AVQMVRAALD KVPALNPHQI DDLMMGCGLP GGESGFNIAR VVAVALGYDF LPGTTVNRYC SSSLQTTRMA FHAIKAGEGD AFISAGVETV SRFAKGNSDS WPDTKNPLFD GAQERSAAAA AGADEWHDPR TDQKLPDIYI AMGQTAENVA IMTGISREEQ DRWGVRSQNR AEEAIKNGFF EREITPVTLP DGTTVSTDDG PRPGTTYEKV SELKPAFRPN GTVTAGNACP LNDGAAAVVI TSDTKAKELG LTPLARIVST GVSGLSPEIM GLGPIEASKK ALERAGMAIT DIDLVEINEA FAVQVLGSAR ELGIDEDKLN ISGGAIALGH PFGMTGARIT TTLLNNLQTY DKTFGLETMC VGGGQGMAMV IERLA

NT Sequence
ATGCCAGAAG CTGTCATCGT CTCGACTGCC CGCTCGCCGA TTGGCCGGGC CATGAAAGGA TCGCTGGTCG GCATGCGGCC CGACGACCTG GCCGTCCAGA TGGTGCGCGC CGCGCTCGAC AAGGTTCCGG CACTGAACCC CCATCAGATC GACGACCTCA TGATGGGCTG TGGCCTGCCA GGCGGTGAGT CCGGTTTCAA CATCGCCCGT GTCGTCGCCG TCGCGCTCGG CTATGACTTC CTGCCGGGCA CCACGGTCAA CCGGTACTGT TCGTCGTCGC TGCAGACCAC CCGGATGGCC TTCCACGCGA TCAAGGCCGG TGAGGGCGAC GCGTTCATCT CCGCGGGCGT GGAAACCGTC TCCCGGTTCG CCAAGGGAAA CTCCGACTCC TGGCCGGACA CCAAGAACCC GCTGTTCGAC GGGGCTCAGG AACGTTCGGC CGCGGCAGCC GCCGGCGCCG ACGAATGGCA CGATCCCCGC ACCGATCAGA AGCTGCCGGA CATCTATATT GCGATGGGCC AGACCGCGGA AAACGTCGCC ATCATGACCG GCATCAGCCG CGAAGAACAG GACCGCTGGG GCGTGCGCAG CCAGAACCGG GCCGAAGAGG CGATCAAGAA CGGGTTCTTC GAACGAGAAA TCACGCCGGT CACCCTTCCG GACGGCACCA CGGTCAGCAC CGACGACGGC CCGCGACCGG GTACCACCTA CGAAAAGGTC AGCGAGCTCA AGCCGGCTTT CCGGCCGAAT GGCACCGTGA CCGCGGGGAA TGCCTGTCCG CTCAACGACG GGGCCGCCGC GGTGGTGATC ACCAGCGACA CCAAGGCCAA GGAATTAGGC TTGACACCGC TGGCGCGCAT TGTGTCCACC GGGGTCAGCG GGCTGTCCCC GGAGATCATG GGCTTAGGGC CGATCGAGGC GTCCAAGAAG GCGCTGGAAA GAGCCGGGAT GGCGATCACC GACATCGACC TGGTCGAGAT CAACGAGGCC TTCGCGGTGC AGGTCCTGGG CTCGGCGCGC GAGCTGGGCA TCGACGAGGA CAAGCTCAAC ATCTCAGGTG GCGCGATCGC CCTAGGTCAC CCGTTCGGTA TGACGGGCGC GCGCATCACC ACCACGCTGT TGAACAACCT GCAGACCTAC GACAAGACGT TCGGTCTGGA AACCATGTGT GTCGGTGGCG GCCAGGGCAT GGCGATGGTG ATCGAGCGCC TCGCG

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