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Seattle Structural Genomics Center for Infectious Disease

MytuD.01026.a: 4-aminobutyrate aminotransferase

Target Characteristics

from organism: Mycobacterium tuberculosis H37Rv
most recent status: purified
center reference id: MytuD.01026.a
is community request: False
associated disease: Tuberculosis
NIH risk group: 2
is select agent: False
NIH priority
pathogens category:
IIIC

Ordering Clones & Proteins

If there are materials available for this target, they will be listed below. Materials can be ordered from SSGCID using the button in the "order material" column. Clicking the button will add the material to a virtual cart. You may order multiple materials at a time at no cost to you, as this contract is funded by NIAID. When you are ready to place your order, click the "Place Order" link which will appear in the top right corner of the page after you place your first item in your cart.

Clones*

CENTER
REFERENCE ID
DOMAIN/REGION
DESCRIPTION
INFO AA
START
AA
STOP
ORDER
MATERIAL
MytuD.01026.a.A1.GE25925 Full length( MytuD.01026.a ) 1 449 GE25925
* SSGCID clones represent un-induced expression constructs which have been verified by sequencing from vector primers. Clones may contain a tag, such as N-term 6xHis. Get sequence information using the button in the "info" column.

Proteins

CENTER
REFERENCE ID
DOMAIN/REGION
DESCRIPTION
INFO AA
START
AA
STOP
ORDER
MATERIAL
MytuD.01026.a.A1.PS00203b Full length( MytuD.01026.a ) 1 449

External Resources

Resource Reference ID
OrthoMCL: OG5_128761
PATRIC ID: fig|83332.12.peg.2898
RefSeq: NP_217105.1
TubercuList: Rv2589
MTB Network Portal: Rv2589
UniProt: P9WQ79

Orthologues for Rv2589

Species % Identity % Coverage Clones Proteins Structures
avium 85 100 1 0 0
paratuberculosis 85 100 0 0 0
leprae 84 100 1 0 0
marinum 84 100 1 1 1
ulcerans 83 100 1 0 0
smegmatis 78 99 0 1 1
smegmatis 69 100 0 1 1
abscessus 64 99 1 1 1
smegmatis 58 98 1 1 0
abscessus 54 98 1 0 0

Enzyme & Pathway Information

Pathway Pathway ID EC Number
superpathway of 4-aminobutanoate degradation 4AMINOBUTMETAB-PWY 2.6.1.19
superpathway of L-arginine, putrescine, and 4-aminobutanoate degradation ARGDEG-PWY 2.6.1.19
beta-alanine degradation I BETA-ALA-DEGRADATION-I-PWY 2.6.1.19
GABA shunt GLUDEG-I-PWY 2.6.1.19
superpathway of L-arginine and L-ornithine degradation ORNARGDEG-PWY 2.6.1.19
nicotine degradation I (pyridine pathway) P181-PWY 2.6.1.19
glutamate degradation IX (via 4-aminobutyrate) PWY3O-210 2.6.1.19
L-glutamate degradation IV PWY-4321 2.6.1.19
4-aminobutanoate degradation V PWY-5022 2.6.1.19
4-aminobutanoate degradation I PWY-6535 2.6.1.19
4-aminobutanoate degradation III PWY-6536 2.6.1.19
4-aminobutanoate degradation II PWY-6537 2.6.1.19
L-valine degradation I VALDEG-PWY 2.6.1.22

Sequences

These sequences are the native gene sequence; sequences of constructs derived from these sequences may differ due to codon optimization or other protocols. To find the specific sequence of any material you may have ordered, click on the "more" button next to the name of that material.
AA Sequence
MASLQQSRRL VTEIPGPASQ ALTHRRAAAV SSGVGVTLPV FVARAGGGIV EDVDGNRLID LGSGIAVTTI GNSSPRVVDA VRTQVAEFTH TCFMVTPYEG YVAVAEQLNR ITPGSGPKRS VLFNSGAEAV ENAVKIARSY TGKPAVVAFD HAYHGRTNLT MALTAKSMPY KSGFGPFAPE IYRAPLSYPY RDGLLDKQLA TNGELAAARA IGVIDKQVGA NNLAALVIEP IQGEGGFIVP AEGFLPALLD WCRKNHVVFI ADEVQTGFAR TGAMFACEHE GPDGLEPDLI CTAKGIADGL PLSAVTGRAE IMNAPHVGGL GGTFGGNPVA CAAALATIAT IESDGLIERA RQIERLVTDR LTTLQAVDDR IGDVRGRGAM IAVELVKSGT TEPDAGLTER LATAAHAAGV IILTCGMFGN IIRLLPPLTI GDELLSEGLD IVCAILADL

NT Sequence
GTGGCCAGCC TGCAGCAGAG TCGGCGCCTG GTCACCGAAA TCCCCGGTCC CGCATCGCAG GCACTGACTC ACCGCCGGGC GGCGGCGGTG TCCAGCGGTG TTGGGGTCAC CCTGCCGGTG TTCGTAGCCC GCGCCGGCGG CGGCATCGTG GAAGACGTGG ACGGTAACCG GCTCATCGAC CTGGGTTCGG GCATCGCAGT GACGACGATC GGCAACTCGT CGCCACGCGT GGTGGATGCG GTGCGCACGC AGGTGGCCGA ATTTACCCAC ACCTGCTTCA TGGTGACGCC ATACGAGGGG TACGTGGCCG TCGCCGAGCA ACTCAACCGG ATTACCCCAG GTTCGGGCCC CAAGCGCTCG GTGTTGTTCA ATTCCGGCGC CGAGGCAGTC GAGAACGCCG TCAAGATCGC ACGCTCCTAC ACCGGCAAGC CCGCGGTGGT GGCGTTCGAC CACGCCTACC ACGGTCGCAC CAACCTAACG ATGGCGCTGA CCGCCAAGTC GATGCCCTAC AAGAGCGGCT TCGGTCCGTT CGCGCCGGAG ATCTACCGAG CGCCATTGTC TTACCCCTAT CGGGACGGCC TCCTCGATAA GCAACTGGCT ACCAATGGTG AGCTAGCCGC GGCCCGAGCC ATCGGCGTCA TCGACAAGCA GGTAGGCGCG AACAACCTGG CCGCCCTCGT CATCGAACCG ATCCAGGGCG AAGGCGGTTT CATCGTTCCG GCCGAAGGGT TCCTACCTGC CCTCCTCGAT TGGTGCCGCA AGAACCATGT GGTGTTCATC GCCGACGAGG TGCAAACCGG CTTTGCCCGT ACCGGGGCGA TGTTCGCCTG CGAGCACGAG GGCCCCGACG GTCTAGAGCC CGACCTGATC TGCACGGCCA AAGGCATCGC CGATGGATTG CCGCTGTCGG CGGTCACCGG CCGCGCCGAG ATCATGAACG CCCCGCACGT GGGCGGCCTG GGCGGCACGT TCGGCGGCAA CCCGGTGGCC TGTGCGGCCG CGCTGGCCAC CATCGCAACC ATCGAAAGCG ACGGGCTGAT CGAGCGGGCC CGCCAGATCG AACGCCTGGT GACCGACCGG TTGACGACGC TGCAGGCCGT CGACGACCGG ATCGGCGACG TGCGTGGTCG CGGCGCCATG ATCGCCGTAG AGCTGGTCAA ATCCGGAACC ACCGAGCCCG ACGCCGGGCT GACCGAGCGG CTGGCGACCG CGGCCCACGC CGCCGGCGTC ATCATTTTGA CCTGCGGCAT GTTCGGCAAC ATCATCCGGC TACTGCCGCC GCTGACCATC GGCGACGAGC TGCTGAGTGA GGGGCTGGAC ATCGTGTGCG CGATCTTGGC CGACCTC

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