NIAID Emerging and Re-emerging Infectious Diseases NIAID Bioinformatics Resource Centers NIAID Structural Genomic Centers Center for Structural Genomics of Infectious Disease
Seattle Structural Genomics Center for Infectious Disease

MytuD.01156.a: O-acetylhomoserine sulfhydrylase MetC

Target Characteristics

from organism: Mycobacterium tuberculosis H37Rv
most recent status: purified
center reference id: MytuD.01156.a
is community request: False
associated disease: Tuberculosis
NIH risk group: 2
is select agent: False
NIH priority
pathogens category:
IIIC

Ordering Clones & Proteins

If there are materials available for this target, they will be listed below. Materials can be ordered from SSGCID using the button in the "order material" column. Clicking the button will add the material to a virtual cart. You may order multiple materials at a time at no cost to you, as this contract is funded by NIAID. When you are ready to place your order, click the "Place Order" link which will appear in the top right corner of the page after you place your first item in your cart.

Proteins

CENTER
REFERENCE ID
DOMAIN/REGION
DESCRIPTION
INFO AA
START
AA
STOP
ORDER
MATERIAL
MytuD.01156.a.A1.PS00164b Full length( MytuD.01156.a ) 1 449

External Resources

Resource Reference ID
OrthoMCL: OG5_130839
PATRIC ID: fig|83332.12.peg.3732
RefSeq: NP_217857.1
TubercuList: Rv3340
MTB Network Portal: Rv3340
UniProt: O53390

Orthologues for Rv3340

Species % Identity % Coverage Clones Proteins Structures
marinum 91 100 1 1 1
ulcerans 91 100 0 0 0
avium 89 100 1 1 0
paratuberculosis 89 100 1 1 0
smegmatis 84 98 0 2 0
thermoresistibile 82 100 0 0 0
abscessus 76 100 1 1 0
smegmatis 50 93 1 1 0

Enzyme & Pathway Information

Pathway Pathway ID EC Number
L-methionine biosynthesis III HSERMETANA-PWY 2.5.1.49
L-homocysteine biosynthesis PWY-5344 2.5.1.49
superpathway of L-methionine biosynthesis (by sulfhydrylation) PWY-5345 2.5.1.49
superpathway of L-cysteine biosynthesis (fungi) PWY-6293 2.5.1.49
S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation II PWY-7174 2.5.1.49
superpathway of sulfur amino acid biosynthesis (Saccharomyces cerevisiae) PWY-821 2.5.1.49

Sequences

These sequences are the native gene sequence; sequences of constructs derived from these sequences may differ due to codon optimization or other protocols. To find the specific sequence of any material you may have ordered, click on the "more" button next to the name of that material.
AA Sequence
MSADSNSTDA DPTAHWSFET KQIHAGQHPD PTTNARALPI YATTSYTFDD TAHAAALFGL EIPGNIYTRI GNPTTDVVEQ RIAALEGGVA ALFLSSGQAA ETFAILNLAG AGDHIVSSPR LYGGTYNLFH YSLAKLGIEV SFVDDPDDLD TWQAAVRPNT KAFFAETISN PQIDLLDTPA VSEVAHRNGV PLIVDNTIAT PYLIQPLAQG ADIVVHSATK YLGGHGAAIA GVIVDGGNFD WTQGRFPGFT TPDPSYHGVV FAELGPPAFA LKARVQLLRD YGSAASPFNA FLVAQGLETL SLRIERHVAN AQRVAEFLAA RDDVLSVNYA GLPSSPWHER AKRLAPKGTG AVLSFELAGG IEAGKAFVNA LKLHSHVANI GDVRSLVIHP ASTTHAQLSP AEQLATGVSP GLVRLAVGIE GIDDILADLE LGFAAARRFS ADPQSVAAF

NT Sequence
ATGAGCGCCG ACAGCAATAG CACCGACGCC GATCCGACCG CGCATTGGTC GTTCGAAACC AAACAGATAC ACGCTGGTCA GCACCCTGAT CCGACCACCA ACGCCCGGGC TCTGCCGATC TATGCGACCA CGTCGTACAC CTTCGACGAC ACCGCGCACG CCGCCGCCCT GTTCGGACTG GAAATTCCGG GCAATATCTA CACCCGGATC GGCAACCCCA CCACCGACGT CGTCGAGCAG CGCATCGCCG CGCTCGAGGG CGGTGTGGCC GCGCTGTTCC TGTCGTCGGG GCAGGCCGCG GAGACGTTCG CCATCTTGAA CCTGGCCGGC GCGGGCGATC ACATCGTGTC CAGCCCGCGC CTGTACGGCG GCACCTACAA CCTGTTCCAC TATTCGCTGG CCAAGCTCGG CATCGAGGTC AGCTTCGTCG ACGATCCGGA CGATCTGGAC ACCTGGCAGG CGGCGGTACG GCCCAACACC AAGGCGTTCT TCGCCGAGAC CATCTCCAAC CCGCAGATCG ACCTGCTGGA CACCCCGGCG GTTTCCGAGG TCGCCCATCG CAACGGGGTG CCGTTGATCG TCGACAACAC CATCGCCACG CCATACCTGA TCCAACCGTT GGCCCAGGGC GCCGACATCG TCGTGCATTC GGCCACCAAG TACCTGGGCG GGCACGGTGC CGCCATCGCG GGTGTGATCG TCGACGGCGG CAACTTCGAT TGGACCCAGG GCCGCTTCCC CGGCTTCACC ACCCCCGACC CCAGCTACCA CGGCGTGGTG TTCGCCGAGC TGGGTCCACC GGCGTTTGCG CTCAAAGCTC GAGTGCAGCT GCTCCGTGAC TACGGCTCGG CGGCTTCGCC GTTCAACGCG TTCTTGGTGG CGCAGGGTCT GGAAACGCTG AGCCTGCGGA TCGAGCGGCA CGTCGCCAAC GCGCAGCGCG TCGCCGAGTT CCTGGCCGCC CGCGACGACG TGCTTTCGGT CAACTATGCG GGGCTGCCCT CCTCGCCCTG GCATGAGCGG GCCAAGAGGC TGGCGCCCAA GGGAACCGGG GCCGTGCTGT CCTTCGAGTT GGCCGGCGGC ATCGAGGCCG GCAAGGCATT CGTGAACGCG TTGAAGCTGC ACAGCCACGT CGCCAACATC GGTGACGTGC GCTCGCTGGT GATCCACCCG GCATCGACCA CTCATGCCCA GCTGAGCCCG GCCGAGCAGC TGGCGACCGG GGTCAGCCCG GGCCTGGTGC GTTTGGCTGT GGGCATCGAA GGTATCGACG ATATCCTGGC CGACCTGGAG CTTGGCTTTG CCGCGGCCCG CAGATTCAGC GCCGACCCGC AGTCCGTGGC GGCGTTC

© 2021 Seattle Children's Research Institute. All rights reserved.