MytuD.01212.a: Malate dehydrogenase
Target Characteristics
| from organism: | Mycobacterium tuberculosis H37Rv |
| most recent status: | purified |
| center reference id: | MytuD.01212.a |
| is community request: | False |
| associated disease: | Tuberculosis |
| NIH risk group: | 2 |
| is select agent: | False |
| NIH priority pathogens category: |
IIIC |
Ordering Clones & Proteins
If there are materials available for this target, they will be listed below.
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Clones*
| CENTER REFERENCE ID |
DOMAIN/REGION DESCRIPTION |
INFO | AA START |
AA STOP |
ORDER MATERIAL |
|---|---|---|---|---|---|
| MytuD.01212.a.A1.GE25949 | Full length( MytuD.01212.a ) | 1 | 329 | GE25949 |
* SSGCID clones represent un-induced expression constructs which have been verified by sequencing from vector primers. Clones may contain a tag, such as N-term 6xHis. Get sequence information
using the button in the "info" column.
Proteins
| CENTER REFERENCE ID |
DOMAIN/REGION DESCRIPTION |
INFO | AA START |
AA STOP |
ORDER MATERIAL |
|---|---|---|---|---|---|
| MytuD.01212.a.A1.PS00155 | Full length( MytuD.01212.a ) | 1 | 329 |
External Resources
| Resource | Reference ID |
|---|---|
| OrthoMCL: | OG5_127410 |
| PATRIC ID: | fig|83332.12.peg.1389 |
| RefSeq: | NP_215756.1 |
| TubercuList: | Rv1240 |
| MTB Network Portal: | Rv1240 |
| UniProt: | P9WK13 |
Orthologues for Rv1240
| Species | % Identity | % Coverage | Clones | Proteins | Structures |
|---|---|---|---|---|---|
| marinum | 94 | 100 | 1 | 0 | 0 |
| ulcerans | 93 | 100 | 0 | 0 | 0 |
| paratuberculosis | 92 | 100 | 1 | 0 | 0 |
| avium | 91 | 100 | 1 | 1 | 0 |
| leprae | 89 | 100 | 1 | 0 | 0 |
Enzyme & Pathway Information
| Pathway | Pathway ID | EC Number |
|---|---|---|
| respiration (anaerobic) | ANARESP1-PWY | 1.1.1.37 |
| mixed acid fermentation | FERMENTATION-PWY | 1.1.1.37 |
| gluconeogenesis I | GLUCONEO-PWY | 1.1.1.37 |
| superpathway of glycolysis, pyruvate dehydrogenase, TCA, and glyoxylate bypass | GLYCOLYSIS-TCA-GLYOX-BYPASS | 1.1.1.37 |
| glyoxylate cycle | GLYOXYLATE-BYPASS | 1.1.1.37 |
| L-aspartate degradation II | MALATE-ASPARTATE-SHUTTLE-PWY | 1.1.1.37 |
| TCA cycle IV (2-oxoglutarate decarboxylase) | P105-PWY | 1.1.1.37 |
| pyruvate fermentation to propanoate I | P108-PWY | 1.1.1.37 |
| reductive TCA cycle I | P23-PWY | 1.1.1.37 |
| incomplete reductive TCA cycle | P42-PWY | 1.1.1.37 |
| formaldehyde assimilation I (serine pathway) | PWY-1622 | 1.1.1.37 |
| L-carnitine degradation III | PWY-3641 | 1.1.1.37 |
| L-glutamate degradation VIII (to propanoate) | PWY-5088 | 1.1.1.37 |
| reductive TCA cycle II | PWY-5392 | 1.1.1.37 |
| superpathway of cytosolic glycolysis (plants), pyruvate dehydrogenase and TCA cycle | PWY-5464 | 1.1.1.37 |
| superpathway of glyoxylate cycle and fatty acid degradation | PWY-561 | 1.1.1.37 |
| TCA cycle II (plants and fungi) | PWY-5690 | 1.1.1.37 |
| partial TCA cycle (obligate autotrophs) | PWY-5913 | 1.1.1.37 |
| Methanobacterium thermoautotrophicum biosynthetic metabolism | PWY-6146 | 1.1.1.37 |
| TCA cycle III (animals) | PWY66-398 | 1.1.1.37 |
| gluconeogenesis III | PWY66-399 | 1.1.1.37 |
| methylaspartate cycle | PWY-6728 | 1.1.1.37 |
| TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase) | PWY-6969 | 1.1.1.37 |
| malate-oxaloacetate shuttle I | PWY-7047 | 1.1.1.37 |
| malate-oxaloacetate shuttle II | PWY-7048 | 1.1.1.37 |
| C4 photosynthetic carbon assimilation cycle, NAD-ME type | PWY-7115 | 1.1.1.37 |
| chitin degradation to ethanol | PWY-7118 | 1.1.1.37 |
| anaerobic energy metabolism (invertebrates, cytosol) | PWY-7383 | 1.1.1.37 |
| anaerobic energy metabolism (invertebrates, mitochondrial) | PWY-7384 | 1.1.1.37 |
| superpathway of anaerobic energy metabolism (invertebrates) | PWY-7389 | 1.1.1.37 |
| TCA cycle I (prokaryotic) | TCA | 1.1.1.37 |
| superpathway of glyoxylate bypass and TCA | TCA-GLYOX-BYPASS | 1.1.1.37 |
Sequences
These sequences are the native gene sequence; sequences of constructs derived from these sequences may differ due to codon optimization or other protocols.
To find the specific sequence of any material you may have ordered, click on the "more" button next to the name of that material.
AA Sequence
MSASPLKVAV TGAAGQIGYS LLFRLASGSL LGPDRPIELR LLEIEPALQA LEGVVMELDD CAFPLLSGVE IGSDPQKIFD GVSLALLVGA RPRGAGMERS DLLEANGAIF TAQGKALNAV AADDVRVGVT GNPANTNALI AMTNAPDIPR ERFSALTRLD HNRAISQLAA KTGAAVTDIK KMTIWGNHSA TQYPDLFHAE VAGKNAAEVV NDQAWIEDEF IPTVAKRGAA IIDARGASSA ASAASATIDA ARDWLLGTPA DDWVSMAVVS DGSYGVPEGL ISSFPVTTKG GNWTIVSGLE IDEFSRGRID KSTAELADER SAVTELGLI
NT Sequence
GTGAGCGCTA GTCCTCTCAA GGTCGCCGTT ACCGGCGCCG CCGGCCAAAT CGGCTACAGC CTGTTGTTCC GCCTGGCCAG CGGCTCTTTG CTGGGCCCTG ACCGTCCGAT CGAGCTGCGG CTGCTCGAGA TCGAGCCGGC ACTGCAGGCG CTCGAGGGTG TGGTGATGGA ACTCGACGAC TGCGCTTTCC CGCTGTTGTC CGGGGTGGAG ATCGGTTCCG ATCCCCAGAA GATCTTCGAT GGTGTGAGCC TGGCCCTGCT GGTCGGAGCC CGCCCCCGGG GCGCGGGCAT GGAGCGAAGT GACCTGCTGG AGGCCAACGG CGCGATCTTC ACCGCTCAGG GCAAAGCCCT CAACGCTGTC GCCGCGGATG ACGTTCGCGT CGGGGTGACC GGCAACCCCG CCAACACCAA CGCGCTGATC GCGATGACCA ATGCGCCCGA CATTCCCCGC GAGCGGTTCT CGGCGCTCAC CCGGCTGGAC CACAATCGGG CGATCTCGCA GCTGGCCGCC AAGACCGGCG CGGCGGTCAC CGACATCAAG AAGATGACGA TCTGGGGCAA TCACTCGGCC ACCCAGTACC CCGACCTGTT CCACGCGGAG GTCGCCGGAA AGAACGCGGC CGAAGTGGTC AACGACCAGG CCTGGATCGA GGATGAATTC ATCCCGACGG TCGCCAAGCG CGGTGCGGCG ATCATCGATG CGCGCGGCGC GTCGTCGGCC GCCTCGGCCG CGTCGGCAAC CATCGACGCT GCCCGGGACT GGTTGCTGGG GACGCCGGCG GACGATTGGG TCTCGATGGC CGTCGTCTCC GACGGGTCCT ACGGGGTGCC GGAGGGCTTG ATCTCCTCGT TTCCGGTCAC CACCAAGGGC GGCAACTGGA CGATCGTGAG CGGCTTGGAG ATCGACGAGT TCTCCCGCGG CCGGATCGAC AAGTCAACCG CCGAGTTGGC TGACGAGCGC AGCGCGGTCA CCGAGCTCGG CCTGATC