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Seattle Structural Genomics Center for Infectious Disease

MytuD.01241.a: PROBABLE THIOSULFATE SULFURTRANSFERASE SSEA (RHODANESE) (THIOSULFATE CYANIDE TRANSSULFURASE) (THIOSULFATE THIOTRANSFERASE)

Target Characteristics

from organism: Mycobacterium tuberculosis H37Rv
most recent status: in PDB
center reference id: MytuD.01241.a
is community request: True
associated disease: Tuberculosis
NIH risk group: 2
is select agent: False
NIH priority
pathogens category:
IIIC

Ordering Clones & Proteins

If there are materials available for this target, they will be listed below. Materials can be ordered from SSGCID using the button in the "order material" column. Clicking the button will add the material to a virtual cart. You may order multiple materials at a time at no cost to you, as this contract is funded by NIAID. When you are ready to place your order, click the "Place Order" link which will appear in the top right corner of the page after you place your first item in your cart.

Clones*

CENTER
REFERENCE ID
DOMAIN/REGION
DESCRIPTION
INFO AA
START
AA
STOP
ORDER
MATERIAL
MytuD.01241.a.A1.GE25951 Full length( MytuD.01241.a ) 1 297 GE25951
* SSGCID clones represent un-induced expression constructs which have been verified by sequencing from vector primers. Clones may contain a tag, such as N-term 6xHis. Get sequence information using the button in the "info" column.

Proteins

CENTER
REFERENCE ID
DOMAIN/REGION
DESCRIPTION
INFO AA
START
AA
STOP
ORDER
MATERIAL
MytuD.01241.a.A1.PS00234 Full length( MytuD.01241.a ) 1 297
MytuD.01241.a.A1.PW26027 Full length( MytuD.01241.a ) 1 297

Structures

image of structure for 3HZU
3HZU
Deposited: 6/24/2009
Determination: XRay
Diffraction Image
Clone: MytuD.01241.a.A1.GE25951
Protein: MytuD.01241.a.A1.PW26027

Publications by SSGCID

Mycobacterium thermoresistibile as a source of thermostable orthologs of Mycobacterium tuberculosis proteins.
Edwards TE, Grundner C, Liao R, Myler PJ, Phan I
Protein Sci. - 2012
volume 21, issue 7, pages 1093-6
PMID: 22544630; PMCID: PMC3403447
PDB: 3HZU, 3P3A

Citations by Others

Challenges and opportunities of automated proteinprotein docking: HDOCK server versus human predictions in CAPRI Rounds 3846
Y Yan, J He, Y Feng, P Lin, H Tao- Proteins: Structure, 2020 - Wiley Online Library
cited by: 4 others
PDB: 3HZU

This list was obtained from Google Scholar searches using the Open Source tool https://github.com/ckreibich/scholar.py and each citation has been manually reviewed.

External Resources

Resource Reference ID
OrthoMCL: OG5_127129
PATRIC ID: fig|83332.12.peg.3670
RefSeq: NP_217800.1
TubercuList: Rv3283
MTB Network Portal: Rv3283
UniProt: P9WHF7

Orthologues for Rv3283

Species % Identity % Coverage Clones Proteins Structures
paratuberculosis 87 99 1 0 0
marinum 85 98 0 0 0
leprae 84 100 1 0 0
ulcerans 84 98 0 0 0
smegmatis 82 99 1 1 0
thermoresistibile 79 99 1 2 1
abscessus 78 100 0 0 0

Enzyme & Pathway Information

Pathway Pathway ID EC Number
thiosulfate disproportionation IV (rhodanese) PWY-5350 2.8.1.1
sulfide oxidation IV (metazoa) PWY-7927 2.8.1.1

Sequences

These sequences are the native gene sequence; sequences of constructs derived from these sequences may differ due to codon optimization or other protocols. To find the specific sequence of any material you may have ordered, click on the "more" button next to the name of that material.
AA Sequence
MPLPADPSPT LSAYAHPERL VTADWLSAHM GAPGLAIVES DEDVLLYDVG HIPGAVKIDW HTDLNDPRVR DYINGEQFAE LMDRKGIARD DTVVIYGDKS NWWAAYALWV FTLFGHADVR LLNGGRDLWL AERRETTLDV PTKTCTGYPV VQRNDAPIRA FRDDVLAILG AQPLIDVRSP EEYTGKRTHM PDYPEEGALR AGHIPTAVHI PWGKAADESG RFRSREELER LYDFINPDDQ TVVYCRIGER SSHTWFVLTH LLGKADVRNY DGSWTEWGNA VRVPIVAGEE PGVVPVV

NT Sequence
GTGCCGCTTC CCGCAGACCC TAGCCCCACC TTGTCGGCCT ACGCCCATCC CGAACGGCTC GTGACCGCCG ACTGGTTGTC GGCACACATG GGCGCGCCGG GCCTGGCGAT CGTCGAATCC GACGAGGACG TCTTGCTCTA CGACGTCGGC CATATTCCCG GCGCCGTCAA GATCGACTGG CACACCGACC TCAACGACCC ACGGGTGCGC GACTACATCA ACGGCGAGCA GTTCGCCGAA TTGATGGACC GCAAGGGCAT CGCCCGCGAT GACACCGTGG TGATCTATGG CGACAAGAGC AATTGGTGGG CCGCCTATGC GTTGTGGGTG TTCACGCTGT TCGGTCACGC CGACGTGCGA CTCCTCAACG GCGGCCGTGA CCTCTGGCTC GCCGAGCGCC GGGAAACCAC CTTGGACGTC CCGACCAAGA CCTGCACCGG TTATCCCGTC GTGCAGCGCA ACGATGCACC CATCCGCGCA TTCAGAGACG ACGTGCTGGC CATCCTGGGC GCTCAGCCGC TGATCGACGT ACGCTCTCCC GAGGAGTACA CCGGCAAGCG CACCCATATG CCCGATTACC CCGAGGAAGG GGCGCTGCGG GCCGGTCACA TCCCCACGGC GGTGCACATT CCGTGGGGGA AGGCCGCCGA CGAAAGTGGA CGGTTTCGCA GCCGCGAGGA ATTGGAACGG CTCTATGACT TCATAAACCC GGACGACCAA ACCGTCGTCT ATTGCCGCAT CGGTGAACGC TCCAGCCATA CCTGGTTCGT GCTCACACAC CTGCTGGGCA AGGCAGATGT ACGGAACTAC GACGGCTCGT GGACCGAGTG GGGCAACGCC GTGCGAGTGC CGATCGTCGC GGGCGAAGAA CCAGGAGTGG TACCCGTCGT A

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