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Seattle Structural Genomics Center for Infectious Disease

MytuD.01549.a: pyruvate phosphate dikinase

Target Characteristics

from organism: Mycobacterium tuberculosis H37Rv
most recent status: purified
center reference id: MytuD.01549.a
is community request: False
associated disease: Tuberculosis
NIH risk group: 2
is select agent: False
NIH priority
pathogens category:
IIIC

Ordering Clones & Proteins

If there are materials available for this target, they will be listed below. Materials can be ordered from SSGCID using the button in the "order material" column. Clicking the button will add the material to a virtual cart. You may order multiple materials at a time at no cost to you, as this contract is funded by NIAID. When you are ready to place your order, click the "Place Order" link which will appear in the top right corner of the page after you place your first item in your cart.

External Resources

Resource Reference ID
OrthoMCL: OG5_127082
PATRIC ID: fig|83332.12.peg.1262
RefSeq: NP_215643.1
TubercuList: Rv1127c
MTB Network Portal: Rv1127c
UniProt: O06579

Orthologues for Rv1127c

Species % Identity % Coverage Clones Proteins Structures
marinum 77 100 1 1 0
ulcerans 77 100 0 0 0
paratuberculosis 77 97 1 0 0
avium 77 96 1 0 0
leprae 72 97 0 0 0
avium 67 97 1 1 0
avium 48 94 1 1 0

Enzyme & Pathway Information

Pathway Pathway ID EC Number
C4 photosynthetic carbon assimilation cycle, NADP-ME type PWY-241 2.7.9.1
starch plastidic translocation I PWY-6240 2.7.9.1
L-glutamine biosynthesis III PWY-6549 2.7.9.1
C4 photosynthetic carbon assimilation cycle, NAD-ME type PWY-7115 2.7.9.1
C4 photosynthetic carbon assimilation cycle, PEPCK type PWY-7117 2.7.9.1

Sequences

These sequences are the native gene sequence; sequences of constructs derived from these sequences may differ due to codon optimization or other protocols. To find the specific sequence of any material you may have ordered, click on the "more" button next to the name of that material.
AA Sequence
MTRITRANGC PDGTLENAVV ALDGGANYPR EILGNKGHGI DMMRRHHLPV PPAFCITTEV GVRYLAAPGS TIAAIWDDVL DRMSWLETET SCTFGRGPNP LLVSVRSGAT QSMPGMMDTI LDVGMTDAVE RVLARPGAAD FAHDTRRRFT SMYRRIVGSA GPITDDPYAQ LRASIEAVFA SWNSPRAVAY RDHHGLDDQG GTAVVVQAMV FGNLTANSGA GVLSSRNPIT GANEPFGEWL PGGQGDDVVS GLVAVAPITA LRDQQPAVYD QLMAAARSLE RMAGDVQEIE FTVEDSQLWL LQTRGAERSA QAAVRLALQL HHEGLIDDTE TLRRVTPTHI ETLLRPSLQT ETRLAAPLLA KGLPACPGVV SGTAYTEVDE ALDAADRGEP VILVRDHTRP EDVMGMLAAQ GIVTEVGGAA SHAAVVSREL GRVAVVGCGP GVAAALAGKE ITVDGYEGEV RQGVLALSAW SESDTPELRE LADIAQRISS

NT Sequence
ATGACTCGTA TCACCCGAGC CAATGGTTGC CCCGACGGAA CTCTCGAAAA CGCCGTTGTG GCGCTGGACG GCGGCGCGAA CTACCCACGC GAGATCCTGG GCAACAAAGG CCACGGCATC GACATGATGC GCCGGCACCA TCTGCCGGTG CCGCCTGCAT TCTGCATTAC CACCGAGGTG GGCGTGCGCT ATCTCGCCGC GCCCGGATCC ACGATCGCCG CGATCTGGGA TGACGTGCTG GATCGGATGA GCTGGCTGGA AACAGAAACC TCGTGCACGT TCGGCCGTGG CCCGAATCCG CTGCTGGTCA GCGTGCGCTC GGGAGCCACC CAGTCGATGC CCGGCATGAT GGACACGATT CTGGACGTGG GCATGACCGA CGCGGTCGAA CGAGTACTTG CCAGGCCGGG TGCCGCCGAC TTCGCCCACG ACACCAGACG GCGATTCACC AGCATGTATC GGCGCATCGT CGGCAGCGCC GGTCCCATTA CCGACGACCC GTATGCCCAG TTGCGCGCGA GCATCGAGGC GGTATTCGCC TCCTGGAACT CACCTCGCGC CGTTGCCTAT CGCGACCATC ACGGCCTCGA CGACCAAGGC GGTACGGCGG TGGTGGTGCA GGCGATGGTA TTCGGCAACC TCACCGCGAA CTCGGGCGCC GGGGTGCTGT CCTCACGCAA CCCGATCACC GGAGCCAACG AACCGTTCGG CGAATGGCTA CCCGGCGGCC AAGGCGACGA CGTGGTGTCC GGATTGGTCG CCGTCGCACC GATCACCGCC CTGCGCGACC AGCAGCCGGC CGTCTACGAC CAACTGATGG CGGCCGCCCG CAGTTTGGAG CGCATGGCAG GCGACGTCCA GGAGATCGAA TTCACCGTGG AGGACAGCCA GCTGTGGCTG CTGCAGACCC GCGGGGCGGA ACGCTCGGCG CAGGCCGCCG TGCGACTGGC GCTGCAACTG CATCACGAGG GACTCATCGA CGACACCGAG ACACTGCGCC GGGTGACTCC GACGCACATC GAGACTTTGC TACGGCCGTC GCTGCAGACG GAAACACGGT TGGCTGCACC GCTTTTGGCC AAGGGCCTGC CCGCTTGCCC GGGCGTGGTA TCCGGGACCG CCTACACCGA GGTGGACGAG GCGCTGGACG CTGCGGACCG GGGCGAGCCG GTCATCTTGG TGCGAGATCA CACCAGACCG GAGGACGTCA TGGGCATGCT TGCCGCGCAA GGCATTGTCA CCGAGGTGGG GGGTGCCGCC AGTCATGCGG CGGTGGTTAG CCGCGAGCTC GGTCGAGTGG CCGTGGTGGG TTGCGGTCCC GGGGTCGCGG CGGCACTGGC CGGCAAGGAG ATCACCGTCG ACGGCTATGA AGGCGAAGTG CGCCAAGGCG TTCTGGCATT GTCTGCCTGG TCGGAAAGTG ACACGCCGGA GTTGCGCGAG CTGGCCGACA TCGCGCAACG GATCAGTTCA

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