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Seattle Structural Genomics Center for Infectious Disease

MytuD.01609.a: POSSIBLE OSMOPROTECTANT (GLYCINE BETAINE/CARNITINE/CHOLINE/L-PROLINE) TRANSPORT ATP-BINDING PROTEIN ABC TRANSPORTER PROV

Target Characteristics

from organism: Mycobacterium tuberculosis H37Rv
most recent status: expressed
center reference id: MytuD.01609.a
is community request: False
associated disease: Tuberculosis
NIH risk group: 2
is select agent: False
NIH priority
pathogens category:
IIIC

Ordering Clones & Proteins

If there are materials available for this target, they will be listed below. Materials can be ordered from SSGCID using the button in the "order material" column. Clicking the button will add the material to a virtual cart. You may order multiple materials at a time at no cost to you, as this contract is funded by NIAID. When you are ready to place your order, click the "Place Order" link which will appear in the top right corner of the page after you place your first item in your cart.

Clones*

CENTER
REFERENCE ID
DOMAIN/REGION
DESCRIPTION
INFO AA
START
AA
STOP
ORDER
MATERIAL
MytuD.01609.a.B1.GE26991 Full length( MytuD.01609.a ) 1 376 GE26991
* SSGCID clones represent un-induced expression constructs which have been verified by sequencing from vector primers. Clones may contain a tag, such as N-term 6xHis. Get sequence information using the button in the "info" column.

External Resources

Resource Reference ID
OrthoMCL: OG5_135381
PATRIC ID: fig|83332.12.peg.4187
RefSeq: NP_218275.1
TubercuList: Rv3758c
MTB Network Portal: Rv3758c
UniProt: O69724

Orthologues for Rv3758c

Species % Identity % Coverage Clones Proteins Structures
marinum 79 96 1 0 0
paratuberculosis 79 73 1 0 0
avium 78 96 1 0 0
fortuitum 76 38 0 0 0
smegmatis 67 95 0 0 0
abscessus 66 95 1 0 0
abscessus 49 79 1 0 0
marinum 48 78 1 0 0
smegmatis 38 55 0 0 0
smegmatis 32 54 0 0 0

Enzyme & Pathway Information

Pathway Pathway ID EC Number
7.6.2.9

Sequences

These sequences are the native gene sequence; sequences of constructs derived from these sequences may differ due to codon optimization or other protocols. To find the specific sequence of any material you may have ordered, click on the "more" button next to the name of that material.
AA Sequence
MICFDDVSKV YAHGATAVDR LTLEVPNGML TVFVGPSGCG KTTALRMINR MVDPTSGTIT VDGTDVSTVN AVKLRLGIGY VIQNAGLMPH QRVIDNVATV PVLKGQPRRA ARKAGYEVLE RVGLDPKVAT RYPAQLSGGE QQRVGVARAL AADPPILLMD EPFSAVDPVV RHELQNEILR LQAELHKTIV FVTHDIDEAL KLADLVAVFA PGGALAQYDE TARLLSSPAN DFVSKFIGLG RGYRWLQLFD AAGLPVRDIE QVSVNGLSDA RDRQVRDGWV LVVDGAGAPL GWIDADGRRR HRGGAALSDA MTVGGSVFRP NGNLSQALDA ALSSPSGVGV AVDGGGKVIG GILAADVLAE FQKGKKAGGG AKPCTT

NT Sequence
TTGATCTGCT TTGACGATGT CAGCAAGGTG TACGCACACG GTGCCACCGC CGTAGACCGG CTGACGCTGG AAGTCCCTAA CGGCATGCTG ACCGTCTTCG TCGGCCCCTC CGGCTGCGGC AAGACGACGG CGCTGCGAAT GATCAACCGA ATGGTGGATC CGACCTCGGG CACCATCACT GTCGACGGTA CCGACGTGTC GACGGTCAAT GCGGTGAAGC TGCGCCTGGG AATTGGCTAT GTCATCCAGA ACGCGGGGCT GATGCCTCAT CAACGGGTCA TCGACAACGT CGCAACGGTG CCGGTGCTGA AGGGTCAGCC GCGCCGGGCA GCCCGCAAAG CCGGTTATGA GGTGCTTGAG CGTGTCGGGC TGGACCCCAA GGTCGCCACC CGCTACCCGG CCCAGCTCTC GGGCGGCGAA CAGCAACGGG TCGGCGTGGC ACGGGCACTC GCGGCCGATC CGCCGATCTT GTTGATGGAC GAGCCGTTCT CGGCCGTCGA CCCGGTGGTT CGCCACGAGC TACAGAACGA AATACTTCGT CTGCAAGCCG AGTTGCACAA GACCATTGTC TTCGTGACGC ACGACATCGA CGAGGCGTTG AAGCTCGCCG ATCTGGTGGC GGTGTTCGCC CCGGGCGGCG CGCTTGCGCA GTACGACGAA ACTGCCCGGC TGTTATCCAG TCCGGCGAAT GACTTCGTGT CGAAGTTCAT CGGTCTCGGT CGCGGCTATC GGTGGCTGCA GCTGTTCGAC GCGGCCGGAC TACCTGTGCG CGACATCGAG CAAGTCTCGG TGAACGGCCT TTCCGATGCC CGGGACAGGC AAGTTCGTGA CGGCTGGGTG CTGGTGGTCG ACGGTGCGGG TGCGCCGTTG GGCTGGATCG ACGCCGATGG CCGGCGGCGT CACCGCGGCG GCGCGGCATT GTCGGATGCC ATGACCGTCG GCGGTTCGGT GTTCCGCCCG AACGGTAACC TCAGCCAGGC GCTGGACGCC GCCTTGTCCT CGCCGTCGGG GGTCGGTGTC GCCGTTGACG GCGGTGGCAA GGTCATCGGC GGGATACTGG CCGCCGACGT GCTGGCCGAG TTCCAAAAAG GCAAGAAGGC CGGCGGCGGA GCTAAGCCAT GCACTACC

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