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Seattle Structural Genomics Center for Infectious Disease

MytuD.01635.a: PROBABLE RUBREDOXIN RUBB

Target Characteristics

from organism: Mycobacterium tuberculosis H37Rv
most recent status: in PDB
center reference id: MytuD.01635.a
is community request: False
associated disease: Tuberculosis
NIH risk group: 2
is select agent: False
NIH priority
pathogens category:
IIIC

Ordering Clones & Proteins

If there are materials available for this target, they will be listed below. Materials can be ordered from SSGCID using the button in the "order material" column. Clicking the button will add the material to a virtual cart. You may order multiple materials at a time at no cost to you, as this contract is funded by NIAID. When you are ready to place your order, click the "Place Order" link which will appear in the top right corner of the page after you place your first item in your cart.

Clones*

CENTER
REFERENCE ID
DOMAIN/REGION
DESCRIPTION
INFO AA
START
AA
STOP
ORDER
MATERIAL
MytuD.01635.a.A1.GE26576 Full length( MytuD.01635.a ) 1 60 GE26576
* SSGCID clones represent un-induced expression constructs which have been verified by sequencing from vector primers. Clones may contain a tag, such as N-term 6xHis. Get sequence information using the button in the "info" column.

Proteins

CENTER
REFERENCE ID
DOMAIN/REGION
DESCRIPTION
INFO AA
START
AA
STOP
ORDER
MATERIAL
MytuD.01635.a.A1.PW26646 Full length( MytuD.01635.a ) 1 60

Structures

image of structure for 2KN9
2KN9
Deposited: 8/20/2009
Determination: NMR
Clone: MytuD.01635.a.A1.GE26576
Protein: MytuD.01635.a.A1.PB00042

Publications by SSGCID

Solution-state NMR structure and biophysical characterization of zinc-substituted rubredoxin B (Rv3250c) from Mycobacterium tuberculosis.
Buchko GW, Hewitt SN, Myler PJ, Napuli AJ, Van Voorhis WC
Acta Crystallogr. Sect. F Struct. Biol. Cryst. Commun. - 2011
volume 67, issue Pt 9, pages 1148-53
PMID: 21904065; PMCID: PMC3169417
PDB: 2KN9

Citations by Others

Rubredoxins derivatives: Simple sulphur-rich coordination metal sites and its relevance for biology and chemistry
BK Maiti, RM Almeida, I Moura, JJG Moura- Coordination Chemistry, 2017 - Elsevier
cited by: 4 others
PDB: 2KN9
Redox Proteins of Mycobacterium tuberculosis
S Phulera, M Akif, AA Sardesai? - Journal of the Indian Institute of Science, 2014 - journal.iisc.ernet.in
PDB: 2KN9

This list was obtained from Google Scholar searches using the Open Source tool https://github.com/ckreibich/scholar.py and each citation has been manually reviewed.

External Resources

Resource Reference ID
OrthoMCL: OG5_132030
PATRIC ID: fig|83332.12.peg.3634
RefSeq: NP_217767.1
TubercuList: Rv3250c
MTB Network Portal: Rv3250c
UniProt: I6YFL7

Orthologues for Rv3250c

Species % Identity % Coverage Clones Proteins Structures
avium 90 98 1 0 0
thermoresistibile 88 97 1 1 0
smegmatis 81 98 1 0 0
abscessus 79 97 1 0 0

Sequences

These sequences are the native gene sequence; sequences of constructs derived from these sequences may differ due to codon optimization or other protocols. To find the specific sequence of any material you may have ordered, click on the "more" button next to the name of that material.
AA Sequence
MNDYKLFRCI QCGFEYDEAL GWPEDGIAAG TRWDDIPDDW SCPDCGAAKS DFEMVEVARS

NT Sequence
GTGAACGACT ACAAACTGTT CCGCTGTATC CAATGCGGCT TTGAGTACGA TGAGGCGCTG GGTTGGCCGG AGGACGGCAT CGCGGCCGGC ACCCGCTGGG ACGACATCCC CGATGACTGG AGTTGCCCGG ATTGCGGTGC GGCAAAGTCG GATTTCGAGA TGGTGGAGGT GGCTCGCTCG

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