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Seattle Structural Genomics Center for Infectious Disease

MytuD.01649.a: Putative conserved protein Rv2377c

Target Characteristics

from organism: Mycobacterium tuberculosis H37Rv
most recent status: in PDB
center reference id: MytuD.01649.a
is community request: True
associated disease: Tuberculosis
NIH risk group: 2
is select agent: False
NIH priority
pathogens category:
IIIC

Ordering Clones & Proteins

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Structures

image of structure for 2KHR
2KHR
Deposited: 4/10/2009
Determination: NMR
Clone: MytuD.01649.a.M1.GE00001
Protein: MytuD.01649.a.M1.PB00023

Publications by SSGCID

Solution structure of Rv2377c-founding member of the MbtH-like protein family.
Buchko GW, Kim CY, Myler PJ, Terwilliger TC
Tuberculosis (Edinb) - 2010
volume 90, issue 4, pages 245-51
PMID: 20434955; PMCID: PMC2910232
PDB: 2KHR

Citations by Others

Identification of outer membrane and exoproteins of carbapenem-resistant multilocus sequence type 258 Klebsiella pneumoniae
AJ Brinkworth, CH Hammer, LR Olano, SD Kobayashi- PloS one, 2015 - ncbi.nlm.nih.gov
cited by: 19 others
PDB: 2KHR

This list was obtained from Google Scholar searches using the Open Source tool https://github.com/ckreibich/scholar.py and each citation has been manually reviewed.

External Resources

Resource Reference ID
OrthoMCL: OG5_160502
PATRIC ID: fig|83332.12.peg.2658
RefSeq: NP_216893.1
TubercuList: Rv2377c
MTB Network Portal: Rv2377c
UniProt: P9WIP5

Orthologues for Rv2377c

Species % Identity % Coverage Clones Proteins Structures
avium 78 97 1 1 0
avium 78 97 1 1 1
smegmatis 78 96 1 1 0
marinum 76 100 0 0 0
smegmatis 76 99 1 0 0
thermoresistibile 76 99 0 0 0
ulcerans 75 100 0 0 0
abscessus 74 99 0 0 0
thermoresistibile 74 99 0 0 0
ulcerans 72 100 0 0 0
marinum 72 96 1 1 1
avium 71 96 1 0 0
paratuberculosis 71 96 1 0 0
marinum 70 100 0 0 0
abscessus 70 99 0 0 0
marinum 70 97 0 0 0
abscessus 69 96 1 1 0
marinum 68 96 0 0 0
smegmatis 63 94 0 0 0

Sequences

These sequences are the native gene sequence; sequences of constructs derived from these sequences may differ due to codon optimization or other protocols. To find the specific sequence of any material you may have ordered, click on the "more" button next to the name of that material.
AA Sequence
MSTNPFDDDN GAFFVLVNDE DQHSLWPVFA DIPAGWRVVH GEASRAACLD YVEKNWTDLR PKSLRDAMVE D

NT Sequence
gtgagcacca atcctttcga tgacgacaac ggcgcattct tcgtgctggt caacgacgaa gaccagcaca gcctgtggcc ggtgttcgcc gatatcccgg ccggctggcg cgtggtgcac ggcgaagcca gccgtgccgc ctgcctggac tacgtggaaa agaactggac cgatctgcgg ccgaagagcc tgcgtgacgc catggtcgag gactga

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