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Seattle Structural Genomics Center for Infectious Disease

MytuD.10520.b: POSSIBLE GLYOXALASE II (HYDROXYACYLGLUTATHIONE HYDROLASE) (GLX II)(putative beta-lactamase)

Target Characteristics

from organism: Mycobacterium tuberculosis H37Rv
most recent status: expressed
center reference id: MytuD.10520.b
is community request: True
associated disease: Tuberculosis
NIH risk group: 2
is select agent: False
NIH priority
pathogens category:
IIIC

Ordering Clones & Proteins

If there are materials available for this target, they will be listed below. Materials can be ordered from SSGCID using the button in the "order material" column. Clicking the button will add the material to a virtual cart. You may order multiple materials at a time at no cost to you, as this contract is funded by NIAID. When you are ready to place your order, click the "Place Order" link which will appear in the top right corner of the page after you place your first item in your cart.

Clones*

CENTER
REFERENCE ID
DOMAIN/REGION
DESCRIPTION
INFO AA
START
AA
STOP
ORDER
MATERIAL
MytuD.10520.b.A2.GE27894 Mature protein( MytuD.10520.b ) 19 224 GE27894
* SSGCID clones represent un-induced expression constructs which have been verified by sequencing from vector primers. Clones may contain a tag, such as N-term 6xHis. Get sequence information using the button in the "info" column.

External Resources

Resource Reference ID
OrthoMCL: OG5_127147
PATRIC ID: fig|83332.12.peg.2890
RefSeq: NP_217097.1
TubercuList: Rv2581c
MTB Network Portal: Rv2581c
UniProt: P9WMW3

Orthologues for Rv2581c

Species % Identity % Coverage Clones Proteins Structures
marinum 88 100 1 0 0
ulcerans 87 100 0 0 0
avium 84 99 1 0 0
paratuberculosis 83 99 0 0 0
leprae 82 99 1 0 0
smegmatis 71 100 0 0 0
abscessus 59 100 1 2 0

Sequences

These sequences are the native gene sequence; sequences of constructs derived from these sequences may differ due to codon optimization or other protocols. To find the specific sequence of any material you may have ordered, click on the "more" button next to the name of that material.
AA Sequence
MLITGFPAGL LACNCYVLAE RPGTDAVIVD PGQGAMGTLR RILDKNRLTP AAVLLTHGHI DHIWSAQKVS DTFGCPTYVH PADRFMLTDP IYGLGPRIAQ LVAGAFFREP KQVVELDRDG DKIDLGGISV NIDHTPGHTR GSVVFRVLQA TNNDKDIVFT GDTLFERAIG RTDLAGGSGR DLLRSIVDKL LVLDDSTVVL PGHGNSTTIG AERRFNPFLE GLSR

NT Sequence
GTGTTGATCA CCGGATTTCC TGCGGGGTTG CTGGCGTGTA ACTGTTATGT GCTGGCCGAG CGGCCCGGAA CCGACGCCGT CATCGTCGAT CCGGGCCAGG GTGCGATGGG CACGCTGCGT CGCATCCTCG ACAAGAACCG GCTGACCCCT GCCGCGGTGC TGCTCACCCA CGGACACATC GATCACATCT GGTCCGCGCA GAAGGTCTCA GACACCTTCG GCTGCCCCAC CTATGTGCAT CCCGCCGACC GGTTCATGCT GACCGACCCC ATCTACGGCC TGGGCCCGCG GATAGCGCAG CTGGTTGCGG GTGCGTTCTT TCGTGAGCCT AAACAGGTTG TGGAGCTGGA CCGAGACGGC GACAAGATCG ACCTCGGCGG CATCTCGGTC AACATCGATC ACACACCGGG TCACACCCGC GGGTCGGTGG TCTTCCGGGT CCTGCAGGCG ACCAACAACG ACAAGGACAT CGTGTTCACC GGTGACACCC TGTTCGAGCG TGCGATAGGC CGCACCGACT TGGCCGGCGG CAGCGGCCGC GACCTGTTGC GCTCCATCGT CGACAAACTC CTGGTGCTCG ACGACAGCAC GGTGGTGCTG CCCGGGCACG GCAACTCCAC CACCATTGGG GCCGAGCGGC GCTTCAATCC GTTCCTTGAG GGCTTGAGCC GG

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