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Seattle Structural Genomics Center for Infectious Disease

MytuD.10611.b: POSSIBLE ZINC-CONTAINING ALCOHOL DEHYDROGENASE NAD DEPENDENT ADHB

Target Characteristics

from organism: Mycobacterium tuberculosis H37Rv
most recent status: expressed
center reference id: MytuD.10611.b
is community request: True
associated disease: Tuberculosis
NIH risk group: 2
is select agent: False
NIH priority
pathogens category:
IIIC

Ordering Clones & Proteins

If there are materials available for this target, they will be listed below. Materials can be ordered from SSGCID using the button in the "order material" column. Clicking the button will add the material to a virtual cart. You may order multiple materials at a time at no cost to you, as this contract is funded by NIAID. When you are ready to place your order, click the "Place Order" link which will appear in the top right corner of the page after you place your first item in your cart.

Clones*

CENTER
REFERENCE ID
DOMAIN/REGION
DESCRIPTION
INFO AA
START
AA
STOP
ORDER
MATERIAL
MytuD.10611.b.A1.GE27896 Full length( MytuD.10611.b ) 1 375 GE27896
* SSGCID clones represent un-induced expression constructs which have been verified by sequencing from vector primers. Clones may contain a tag, such as N-term 6xHis. Get sequence information using the button in the "info" column.

External Resources

Resource Reference ID
OrthoMCL: OG5_127257
PATRIC ID: fig|83332.12.peg.851
RefSeq: YP_177754.1
TubercuList: Rv0761c
MTB Network Portal: Rv0761c
UniProt: P9WQC7

Orthologues for Rv0761c

Species % Identity % Coverage Clones Proteins Structures
avium 87 100 1 0 0
marinum 87 100 1 0 0
ulcerans 87 100 1 0 0
thermoresistibile 84 100 2 1 0
smegmatis 81 100 0 0 0
abscessus 59 100 1 0 0
smegmatis 58 100 0 0 0
thermoresistibile 57 100 1 0 0
marinum 51 99 1 0 0
paratuberculosis 46 99 1 1 0
avium 45 99 1 0 0
avium 45 97 1 0 0
marinum 44 99 1 0 0
ulcerans 43 99 0 0 0

Enzyme & Pathway Information

Pathway Pathway ID EC Number
ethanol degradation I ETOH-ACETYLCOA-ANA-PWY 1.1.1.1
mixed acid fermentation FERMENTATION-PWY 1.1.1.1
heterolactic fermentation P122-PWY 1.1.1.1
acetylene degradation (anaerobic) P161-PWY 1.1.1.1
superpathway of N-acetylneuraminate degradation P441-PWY 1.1.1.1
hexitol fermentation to lactate, formate, ethanol and acetate P461-PWY 1.1.1.1
D-camphor degradation P601-PWY 1.1.1.1
ethanolamine utilization PWY0-1477 1.1.1.1
L-tryptophan degradation V (side chain pathway) PWY-3162 1.1.1.1
L-tyrosine degradation III PWY3O-4108 1.1.1.1
superpathway of fermentation (Chlamydomonas reinhardtii) PWY4LZ-257 1.1.1.1
L-valine degradation II PWY-5057 1.1.1.1
L-leucine degradation III PWY-5076 1.1.1.1
L-isoleucine degradation II PWY-5078 1.1.1.1
L-phenylalanine degradation III PWY-5079 1.1.1.1
L-methionine degradation III PWY-5082 1.1.1.1
pyruvate fermentation to ethanol I PWY-5480 1.1.1.1
pyruvate fermentation to ethanol II PWY-5486 1.1.1.1
phenylethanol biosynthesis PWY-5751 1.1.1.1
acetoin degradation PWY-6028 1.1.1.1
serotonin degradation PWY-6313 1.1.1.1
acetaldehyde biosynthesis I PWY-6333 1.1.1.1
noradrenaline and adrenaline degradation PWY-6342 1.1.1.1
pyruvate fermentation to ethanol III PWY-6587 1.1.1.1
superpathway of Clostridium acetobutylicum solventogenic fermentation PWY-6594 1.1.1.1
superpathway of Clostridium acetobutylicum acidogenic and solventogenic fermentation PWY-6604 1.1.1.1
ethanol degradation II PWY66-21 1.1.1.1
phytol degradation PWY66-389 1.1.1.1
salidroside biosynthesis PWY-6802 1.1.1.1
3-methylbutanol biosynthesis (engineered) PWY-6871 1.1.1.1
(S)-propane-1,2-diol degradation PWY-7013 1.1.1.1
pyruvate fermentation to isobutanol (engineered) PWY-7111 1.1.1.1
chitin degradation to ethanol PWY-7118 1.1.1.1
superpathway of anaerobic sucrose degradation PWY-7345 1.1.1.1
butanol and isobutanol biosynthesis (engineered) PWY-7396 1.1.1.1
dehydrodiconiferyl alcohol degradation PWY-7557 1.1.1.1

Sequences

These sequences are the native gene sequence; sequences of constructs derived from these sequences may differ due to codon optimization or other protocols. To find the specific sequence of any material you may have ordered, click on the "more" button next to the name of that material.
AA Sequence
MKTKGALIWE FNQPWSVEEI EIGDPRKDEV KIQMEAAGMC RSDHHLVTGD IPMAGFPVLG GHEGAGIVTE VGPGVDDFAP GDHVVLAFIP SCGKCPSCQA GMRNLCDLGA GLLAGESVTD GSFRIQARGQ NVYPMTLLGT FSPYMVVHRS SVVKIDPSVP FEVACLVGCG VTTGYGSAVR TADVRPGDDV AIVGLGGVGM AALQGAVSAG ARYVFAVEPV EWKRDQALKF GATHVYPDIN AALMGIAEVT YGLMAQKVII TVGKLDGADV DSYLTITAKG GTCVLTAIGS LVDTQVTLNL AMLTLLQKNI QGTIFGGGNP HYDIPKLLSM YKAGKLNLDD MVTTAYKLEQ INDGYQDMLN GKNIRGVIRY TDDDR

NT Sequence
GTGAAGACCA AGGGCGCACT GATCTGGGAG TTCAACCAGC CATGGTCCGT CGAAGAGATC GAAATCGGCG ACCCGCGCAA GGACGAAGTC AAGATCCAGA TGGAAGCGGC TGGGATGTGC CGCTCCGACC ATCACCTGGT GACGGGCGAC ATCCCGATGG CGGGCTTTCC CGTTCTGGGC GGACACGAGG GCGCGGGCAT CGTCACCGAG GTCGGCCCGG GAGTCGACGA CTTCGCCCCG GGCGATCACG TGGTGTTGGC ATTCATCCCG TCCTGCGGCA AGTGTCCGTC CTGCCAGGCT GGAATGCGGA ATCTGTGCGA CCTGGGGGCG GGGCTGCTCG CCGGGGAATC TGTGACGGAC GGCTCCTTCC GGATTCAGGC TCGCGGCCAG AACGTCTACC CGATGACCCT GCTCGGAACG TTTTCACCGT ACATGGTGGT GCACCGCAGC TCGGTGGTGA AGATCGACCC GTCGGTGCCC TTCGAAGTCG CCTGCCTGGT TGGTTGCGGC GTCACCACCG GCTATGGTTC GGCGGTCCGC ACGGCCGACG TCCGGCCGGG CGACGACGTG GCCATCGTCG GCTTGGGTGG GGTCGGCATG GCGGCGTTGC AGGGCGCGGT CAGCGCGGGC GCCCGCTACG TCTTCGCGGT GGAGCCGGTG GAATGGAAAC GTGATCAGGC TCTGAAATTC GGTGCCACCC ACGTCTACCC GGACATCAAC GCCGCGCTGA TGGGCATTGC CGAGGTCACC TACGGCCTGA TGGCGCAGAA GGTGATCATC ACCGTCGGCA AGCTCGATGG CGCCGACGTC GACAGCTATC TGACCATCAC GGCCAAGGGC GGCACCTGCG TGCTGACGGC CATCGGCAGC CTGGTCGACA CCCAGGTGAC GCTGAACCTC GCGATGTTGA CCCTGCTGCA AAAGAACATC CAGGGCACCA TCTTCGGCGG CGGCAACCCG CACTACGACA TTCCGAAGCT GTTGTCGATG TATAAGGCCG GCAAACTCAA CCTCGACGAC ATGGTGACCA CTGCGTACAA GCTGGAGCAG ATCAACGACG GATACCAGGA CATGCTGAAC GGCAAGAACA TTCGCGGCGT GATCCGGTAC ACGGACGACG ACCGC

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