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Seattle Structural Genomics Center for Infectious Disease

MytuD.10611.c: Putative alcohol dehydrogenase D

Target Characteristics

from organism: Mycobacterium tuberculosis H37Rv
most recent status: expressed
center reference id: MytuD.10611.c
is community request: True
associated disease: Tuberculosis
NIH risk group: 2
is select agent: False
NIH priority
pathogens category:
IIIC

Ordering Clones & Proteins

If there are materials available for this target, they will be listed below. Materials can be ordered from SSGCID using the button in the "order material" column. Clicking the button will add the material to a virtual cart. You may order multiple materials at a time at no cost to you, as this contract is funded by NIAID. When you are ready to place your order, click the "Place Order" link which will appear in the top right corner of the page after you place your first item in your cart.

Clones*

CENTER
REFERENCE ID
DOMAIN/REGION
DESCRIPTION
INFO AA
START
AA
STOP
ORDER
MATERIAL
MytuD.10611.c.B1.GE37757 full length 1 368 GE37757
* SSGCID clones represent un-induced expression constructs which have been verified by sequencing from vector primers. Clones may contain a tag, such as N-term 6xHis. Get sequence information using the button in the "info" column.

External Resources

Resource Reference ID
PATRIC ID: fig|83332.12.peg.3442
RefSeq: NP_217602.1
RefSeq: YP_006516547.1
TubercuList: Rv3086
MTB Network Portal: Rv3086
UniProt: P9WQB9

Orthologues for Rv3086

Species % Identity % Coverage Clones Proteins Structures
marinum 86 100 1 0 0
smegmatis 73 100 0 0 0
abscessus 51 99 1 0 0
marinum 47 99 1 0 0
smegmatis 47 99 0 0 0
ulcerans 46 99 1 0 0

Enzyme & Pathway Information

Pathway Pathway ID EC Number
ethanol degradation I ETOH-ACETYLCOA-ANA-PWY 1.1.1.1
mixed acid fermentation FERMENTATION-PWY 1.1.1.1
heterolactic fermentation P122-PWY 1.1.1.1
acetylene degradation (anaerobic) P161-PWY 1.1.1.1
superpathway of N-acetylneuraminate degradation P441-PWY 1.1.1.1
hexitol fermentation to lactate, formate, ethanol and acetate P461-PWY 1.1.1.1
D-camphor degradation P601-PWY 1.1.1.1
ethanolamine utilization PWY0-1477 1.1.1.1
L-tryptophan degradation V (side chain pathway) PWY-3162 1.1.1.1
L-tyrosine degradation III PWY3O-4108 1.1.1.1
superpathway of fermentation (Chlamydomonas reinhardtii) PWY4LZ-257 1.1.1.1
L-valine degradation II PWY-5057 1.1.1.1
L-leucine degradation III PWY-5076 1.1.1.1
L-isoleucine degradation II PWY-5078 1.1.1.1
L-phenylalanine degradation III PWY-5079 1.1.1.1
L-methionine degradation III PWY-5082 1.1.1.1
pyruvate fermentation to ethanol I PWY-5480 1.1.1.1
pyruvate fermentation to ethanol II PWY-5486 1.1.1.1
phenylethanol biosynthesis PWY-5751 1.1.1.1
acetoin degradation PWY-6028 1.1.1.1
serotonin degradation PWY-6313 1.1.1.1
acetaldehyde biosynthesis I PWY-6333 1.1.1.1
noradrenaline and adrenaline degradation PWY-6342 1.1.1.1
pyruvate fermentation to ethanol III PWY-6587 1.1.1.1
superpathway of Clostridium acetobutylicum solventogenic fermentation PWY-6594 1.1.1.1
superpathway of Clostridium acetobutylicum acidogenic and solventogenic fermentation PWY-6604 1.1.1.1
ethanol degradation II PWY66-21 1.1.1.1
phytol degradation PWY66-389 1.1.1.1
salidroside biosynthesis PWY-6802 1.1.1.1
3-methylbutanol biosynthesis (engineered) PWY-6871 1.1.1.1
(S)-propane-1,2-diol degradation PWY-7013 1.1.1.1
pyruvate fermentation to isobutanol (engineered) PWY-7111 1.1.1.1
chitin degradation to ethanol PWY-7118 1.1.1.1
superpathway of anaerobic sucrose degradation PWY-7345 1.1.1.1
butanol and isobutanol biosynthesis (engineered) PWY-7396 1.1.1.1
dehydrodiconiferyl alcohol degradation PWY-7557 1.1.1.1

Sequences

These sequences are the native gene sequence; sequences of constructs derived from these sequences may differ due to codon optimization or other protocols. To find the specific sequence of any material you may have ordered, click on the "more" button next to the name of that material.
AA Sequence
MKTTAAVLFE AGKPFELMEL DLDGPGPGEV LVKYTAAGLC HSDLHLTDGD LPPRFPIVGG HEGSGVIEEV GAGVTRVKPG DHVVCSFIPN CGTCRYCCTG RQNLCDMGAT ILEGCMPDGS FRFHSQGTDF GAMCMLGTFA ERATVSQHSV VKVDDWLPLE TAVLVGCGVP SGWGTAVNAG NLRAGDTAVI YGVGGLGINA VQGATAAGCK YVVVVDPVAF KRETALKFGA THAFADAASA AAKVDELTWG QGADAALILV GTVDDEVVSA ATAVIGKGGT VVITGLADPA KLTVHVSGTD LTLHEKTIKG SLFGSCNPQY DIVRLLRLYD AGQLMLDELV TTTYNLEQVN QGYQDLRDGK NIRGVIVH

NT Sequence
atgaaaacca ccgcggcggt actgttcgag gcgggcaaac cgttcgagct gatggagctc gatctcgacg ggccgggtcc gggcgaggtg ttggtcaaat acaccgccgc cgggctgtgc cattccgacc tgcacctcac cgatggtgat ttaccaccgc ggttcccgat cgtgggcggc cacgaagggt ccggggtcat cgaggaggtg ggtgccggcg tcaccagggt caagcccgga gaccacgtgg tgtgcagctt catcccgaac tgcgggactt gccgctactg ctgcaccggc cggcagaacc tgtgcgacat gggggccacc atcctggagg gctgcatgcc ggacggcagt ttccgattcc attcccaggg aacagatttc ggcgccatgt gcatgctggg cacgttcgcc gagcgggcca ccgtctcgca gcattcggtg gtgaaggtgg acgactggct gccactggaa accgcggtgc tggtgggctg cggcgtgccg tccggttggg gcaccgcggt caatgccgga aacctgcggg ccggcgacac cgccgtcatc tacggcgtcg gcggcctggg catcaacgcg gtccagggcg cgaccgccgc cggctgtaag tacgtcgtgg tggtggaccc ggtggctttc aagcgcgaga ccgcgctcaa gttcggcgcc acccatgcct tcgccgacgc cgccagcgcg gcggccaagg tcgacgaact cacctggggg cagggcgccg acgcggcgct gatcctggtg ggcaccgtcg acgacgaggt ggtctcggcc gcgaccgcgg tgatcggcaa gggcggcacc gtcgtcatca ccgggctggc ggacccggcc aaactcaccg tgcacgtctc cggaaccgat ttgacgctgc acgagaaaac gatcaagggc tcgctgttcg gttcctgcaa tccgcaatac gacatcgtgc ggctgctgcg cctctacgac gccggccagc tgatgctgga cgaactcgtg accaccacct acaacctcga acaggtgaac cagggctacc aggatctgcg ggacggcaag aacattcggg gcgtgatcgt gcactga

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