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Seattle Structural Genomics Center for Infectious Disease

MytuD.17208.b: ECF RNA polymerase sigma factor SigH

Target Characteristics

from organism: Mycobacterium tuberculosis H37Rv
most recent status: purified
center reference id: MytuD.17208.b
is community request: True
associated disease: Tuberculosis
NIH risk group: 2
is select agent: False
NIH priority
pathogens category:
IIIC

Ordering Clones & Proteins

If there are materials available for this target, they will be listed below. Materials can be ordered from SSGCID using the button in the "order material" column. Clicking the button will add the material to a virtual cart. You may order multiple materials at a time at no cost to you, as this contract is funded by NIAID. When you are ready to place your order, click the "Place Order" link which will appear in the top right corner of the page after you place your first item in your cart.

Clones*

CENTER
REFERENCE ID
DOMAIN/REGION
DESCRIPTION
INFO AA
START
AA
STOP
ORDER
MATERIAL
MytuD.17208.b.B2.GE39444 soluble domain 16 101 GE39444
MytuD.17208.b.MB1.GE39286 full length 1 216 GE39286
* SSGCID clones represent un-induced expression constructs which have been verified by sequencing from vector primers. Clones may contain a tag, such as N-term 6xHis. Get sequence information using the button in the "info" column.

Proteins

CENTER
REFERENCE ID
DOMAIN/REGION
DESCRIPTION
INFO AA
START
AA
STOP
ORDER
MATERIAL
MytuD.17208.b.MB1.PW37780 full length 1 216

External Resources

Resource Reference ID
PATRIC ID: fig|83332.12.peg.3605
RefSeq: NP_217739.1
RefSeq: YP_006516697.1
RefSeq: WP_003416897.1
TubercuList: Rv3223c
MTB Network Portal: Rv3223c
UniProt: P9WGH9

Orthologues for Rv3223c

Species % Identity % Coverage Clones Proteins Structures
paratuberculosis 94 92 1 1 0
avium 94 92 1 0 0
fortuitum 93 92 1 1 0
marinum 92 100 2 1 0
ulcerans 91 100 1 1 0
smegmatis 88 98 1 0 0
abscessus 84 90 2 0 0
thermoresistibile 83 100 1 0 0

Sequences

These sequences are the native gene sequence; sequences of constructs derived from these sequences may differ due to codon optimization or other protocols. To find the specific sequence of any material you may have ordered, click on the "more" button next to the name of that material.
AA Sequence
MADIDGVTGS AGLQPGPSEE TDEELTARFE RDAIPLLDQL YGGALRMTRN PADAEDLLQE TMVKAYAGFR SFRHGTNLKA WLYRILTNTY INSYRKKQRQ PAEYPTEQIT DWQLASNAEH SSTGLRSAEV EALEALPDTE IKEALQALPE EFRMAVYYAD VEGFPYKEIA EIMDTPIGTV MSRLHRGRRQ LRGLLADVAR DRGFARGEQA HEGVSS

NT Sequence
atggccgaca tcgatggtgt aaccggttcg gcgggtctgc agcctgggcc gtctgaggag acagacgagg agttgaccgc gcgtttcgag cgcgacgcga ttcccctgtt ggaccagctg tacggcggtg cgctgcggat gacgcgcaat ccggccgacg ccgaggactt gctccaggag acgatggtga aggcctatgc gggatttcgt tcgttccggc acggtaccaa tctcaaggcc tggctctacc ggatactgac caacacctac atcaacagct atcgcaagaa acagcggcaa ccggcggagt atccgaccga gcagatcacc gattggcaac tggcgtccaa cgccgagcat tcctcgaccg ggctgcgctc ggctgaagtc gaagcgttag aagcgttgcc ggacaccgag atcaaagagg cgctgcaggc attgccggaa gagttccgga tggcggtcta ctacgccgat gtcgaaggtt tcccctacaa ggagatcgcc gagatcatgg atactccgat cggcaccgtg atgtcgaggc ttcatcgcgg ccgacgtcag ttgcgcggtc ttttagccga tgtggccagg gatcgggggt ttgccagggg cgagcaggcg cacgaggggg tgtcgtcatg a

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