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Seattle Structural Genomics Center for Infectious Disease

MytuD.17261.a: recB Exodeoxyribonuclease V beta chain (EC 3.1.11.5) Rv0630c

Target Characteristics

from organism: Mycobacterium tuberculosis H37Rv
most recent status: soluble
center reference id: MytuD.17261.a
is community request: True
associated disease: Tuberculosis
NIH risk group: 2
is select agent: False
NIH priority
pathogens category:
IIIC

Ordering Clones & Proteins

If there are materials available for this target, they will be listed below. Materials can be ordered from SSGCID using the button in the "order material" column. Clicking the button will add the material to a virtual cart. You may order multiple materials at a time at no cost to you, as this contract is funded by NIAID. When you are ready to place your order, click the "Place Order" link which will appear in the top right corner of the page after you place your first item in your cart.

Clones*

CENTER
REFERENCE ID
DOMAIN/REGION
DESCRIPTION
INFO AA
START
AA
STOP
ORDER
MATERIAL
MytuD.17261.a.A2.GE30113 UvrD-like helicase ATP-binding domain 1 326 GE30113
MytuD.17261.a.A3.GE30114 UvrD-like helicase C-terminal domain 357 613 GE30114
MytuD.17261.a.A4.GE30115 Phage-type/RecB exonuclease C-terminal 764 1089 GE30115
* SSGCID clones represent un-induced expression constructs which have been verified by sequencing from vector primers. Clones may contain a tag, such as N-term 6xHis. Get sequence information using the button in the "info" column.

External Resources

Resource Reference ID
OrthoMCL: OG5_140510
PATRIC ID: fig|83332.12.peg.702
RefSeq: NP_215144.1
TubercuList: Rv0630c
MTB Network Portal: Rv0630c
UniProt: P9WMQ3

Orthologues for Rv0630c

Species % Identity % Coverage Clones Proteins Structures
marinum 66 100 0 0 0
smegmatis 66 99 4 2 0

Enzyme & Pathway Information

Pathway Pathway ID EC Number
3.1.11.5

Sequences

These sequences are the native gene sequence; sequences of constructs derived from these sequences may differ due to codon optimization or other protocols. To find the specific sequence of any material you may have ordered, click on the "more" button next to the name of that material.
AA Sequence
MDRFELLGPL PREGTTTVLE ASAGTGKTFA LAGLVTRYLA ETAATLDEML LITFNRAASR ELRERVRGQI VEAVGALQGD APPSGELVEH LLRGSDAERA QKRSRLRDAL ANFDAATIAT THEFCGSVLK SLGVAGDNAA DVELKESLTD LVTEIVDDRY LANFGRQETD PELTYAEALA LALAVVDDPC AQLRPPDPEP GSKAAVRLRF AAEVLEELER RKGRLRAQGF NDLLIRLATA LEAADSPARD RMRERWRIVL VDEFQDTDPM QWRVLERAFS RHSALILIGD PKQAIYGFRG GDIHTYLKAA GTADARYTLG VNWRSDRALV ESLQTVLRDA TLGHADIVVR GTDAHHAGHR LASAPRPAPF RLRVVKRHTL GYDGTAHVPI EALRRHIPDD LAADVAALLA SGATFAGRPV VAADIAVIVE HHKDARACRN ALAEAGIPAI YTGDTDVFAS QAAKDWLCLL EAFDAPQRSG LVRAAACTMF FGETAESLAA EGDALTDRVA GTLREWADHA RHRGVAAVFQ AAQLAGMGRR VLSQRGGERD LTDLAHIAQL LHEAAHRERL GLPGLRDWLR RQAKAGAGPP EHNRRLDSDA AAVQIMTVFV AKGLQFPIVY LPFAFNRNVR SDDILLYHDD GTRCLYIGGK DGGAQRRTVE GLNRVEAAHD NLRLTYVALT RAQSQVVAWW APTFDEVNGG LSRLLRGRRP GQSQVPDRCT PRVTDEQAWA VFAQWEAAGG PSVEESVIGA RSSLEKPVPV PGFEVRHFHR RIDTTWRRTS YSDLVRGSEA VTVTSEPAAG GRADEVEIAV VAAPGSGADL TSPLAALPSG ASFGSLVHAV LETADPAAPD LAAELEAQVR RHAPWWTVDV DHAQLAPELA RALLPMHDTP LGPAAAALTL RQIGVRDRLR ELDFEMPLAG GDLRGRSPDV SLADVGELLA SHLPGDDPLS PYADRLGSAG LGDQPLRGYL AGSIDVVLRL PGQRYLVVDY KTNHLGDTAA DYGFERLTEA MLHSDYPLQA LLYVVVLHRF LRWRQRDYAP ARHLGGVLYL FVRGMCGAAT PVTAGHPAGV FTWNPPTALV VALSDLLDRG RLQS

NT Sequence
atggaccgct tcgagctgct gggcccgttg ccgagggagg gcaccaccac cgtgctggaa gccagcgccg gcaccggtaa gacgttcgcg ctggccggtc tggtcacccg ctatctggcc gaaaccgccg cgacgctcga cgagatgttg ttgatcacgt tcaaccgtgc ggccagccgg gagttacgcg agcgagtgcg cgggcagatc gtcgaggccg tgggcgcgct acaaggcgac gcgccgccga gcggcgagct cgtcgagcac ctgctgcgcg gcagcgacgc cgagcgcgcc cagaagcggt cgcggctgcg tgacgcgctg gccaacttcg acgcggcaac catcgccacc acccacgagt tctgcggctc ggtgttgaaa tccctcggtg tggccggtga caacgccgcc gacgtggagc tcaaggagag ccttaccgac ctggtcactg agatcgtgga cgatcgctat ctggcgaact tcggtcgtca ggagaccgat ccggagctga cctacgccga ggcgctggcc ctggcccttg ccgtcgtcga cgacccgtgc gcccaactgc gcccgcctga tcccgagccc ggcagcaagg cagcggtgcg gctgcgcttt gccgccgagg tgctcgagga actcgagcgc cgcaagggcc ggctgcgtgc gcaaggattc aacgatctgc tgatccgttt ggcgacagcc ctcgaggcgg ccgactcgcc agctcgcgat cggatgcggg aacgctggcg gatcgtgctg gtggacgagt ttcaagatac cgaccccatg cagtggcggg tgctcgagcg cgcgtttagc cggcattcgg cgctgatcct gatcggcgat cccaagcagg cgatctacgg ctttcgcggc ggcgacatcc acacctacct caaggcggcc ggcaccgccg atgcccgcta cacgttgggc gtcaactggc gcagcgaccg ggcgctggtc gagagcctgc agacggtgct gcgcgatgcg accctgggtc acgccgacat cgtcgtccgc ggcaccgacg cccaccacgc cgggcaccgc ctggcctcgg cgccgcgccc ggcgccgttt cggttgcgcg tggtcaaacg gcacacgctc gggtatgacg ggaccgccca cgtcccgatc gaggcgctgc gccggcacat ccccgacgac ctggccgccg acgtcgcggc gctactggcc agcggggcca ccttcgccgg gcggcccgtg gtggccgcag acatcgcggt gatcgtcgag catcacaaag acgcgcgggc gtgccggaat gcgttggcgg aggcgggcat cccggcgatc tacaccggtg acaccgacgt gttcgcctcg caggccgcca aggactggct gtgcctgctg gaggcgttcg acgcgccgca gcgcagcggg ctggtccgcg ccgccgcgtg cacgatgttc ttcggtgaga ccgcggaatc gcttgccgcc gagggcgatg cgctgaccga tcgggtggcc ggcacgttgc gcgagtgggc cgaccacgca cgccatcgcg gtgtggccgc ggtgtttcag gccgctcagc tggccgggat gggccggcgc gtgctgagcc agcgcggcgg cgaacgggac ctgacagacc tggcgcacat tgcgcagctg ctgcacgagg ccgctcatcg cgagcggctc ggcctgcccg ggctgcgcga ttggctgcgc cgccaggcca aggcgggtgc cggcccgccg gaacacaatc gccggttgga cagcgacgcc gcggcggtgc agatcatgac cgtcttcgtg gccaagggac tgcagtttcc catcgtgtat ctgccgttcg ccttcaaccg caacgtccgc agcgacgaca tcctgctgta tcacgacgac ggcacccgct gcctgtacat cggcggcaag gacggcggtg ctcagcggcg caccgttgag gggctgaacc gcgtcgaggc ggcccacgac aacctccggc tcacctatgt cgcgcttacc cgcgcgcaat cgcaggtcgt cgcgtggtgg gcaccgacgt tcgacgaggt caacggcggg ttgtcgcggt tgctgcgcgg gcgccggccc ggccagtcgc aggtaccgga ccggtgtaca ccacgcgtca ccgacgagca ggcctgggcg gtgttcgcgc agtgggaggc cgcgggcggg ccgtcggtcg aggaatcggt catcggtgct cgcagttccc tcgaaaagcc ggtgcccgta cccggtttcg aggttcggca ctttcaccgc cggatcgaca ccacgtggcg gcggacctcg tactcggatc tggtgcgggg ctcggaagcc gtcaccgtca ccagcgagcc ggcggccggc ggccgtgcgg acgaggtgga gatcgccgtc gtcgccgcgc ccggttccgg cgccgatctg acatcaccgc tggccgcgct gccgtcgggg gcgtcgttcg gctcgctggt gcacgcggtg ctcgagaccg cggacccagc cgctcccgat ctggctgccg aactggaagc ccaggtgcgc cggcacgcgc cgtggtggac cgtggacgtc gaccacgcgc agctggctcc cgaactggcc cgagcgttgc tgccgatgca cgacacgccg ctgggacccg ccgccgccgc actgacattg cggcagatcg gtgtgcgtga tcgtctgcgg gagttggact tcgagatgcc gctggccggg ggcgatctgc gcggccggtc cccggacgtg tcgctggccg acgtgggtga gctgctggcg tcgcacctgc ccggcgacga cccgttgtcg ccctacgccg atcggcttgg ttcggccggg ttgggtgatc aaccgctgcg tggctacctg gcggggtcga tcgacgtggt gctgcggcta cccgggcagc gatatctggt ggtcgattac aagaccaatc accttggtga caccgccgcc gattacggct tcgagcggtt gaccgaggcc atgctgcatt cggactaccc actgcaggcg ctgctgtatg ttgttgtgct gcaccgcttt ctgcggtggc ggcagcggga ttacgctccg gcgcgccatc tcggcggggt gctgtacctg tttgtgcggg gcatgtgcgg tgcggcgacg ccggtgacgg ccgggcatcc ggccggtgtg ttcacctgga acccgcccac ggcgttggtg gtggcgctct cggatctgct cgaccgggga aggctgcagt cgtga

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