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Seattle Structural Genomics Center for Infectious Disease

MytuD.17274.a: DNA-directed RNA polymerase subunit beta' Rv0668

Target Characteristics

from organism: Mycobacterium tuberculosis H37Rv
most recent status: crystallized
center reference id: MytuD.17274.a
is community request: True
associated disease: Tuberculosis
NIH risk group: 2
is select agent: False
NIH priority
pathogens category:
IIIC

Ordering Clones & Proteins

If there are materials available for this target, they will be listed below. Materials can be ordered from SSGCID using the button in the "order material" column. Clicking the button will add the material to a virtual cart. You may order multiple materials at a time at no cost to you, as this contract is funded by NIAID. When you are ready to place your order, click the "Place Order" link which will appear in the top right corner of the page after you place your first item in your cart.

External Resources

Resource Reference ID
OrthoMCL: OG5_126637
PATRIC ID: fig|83332.12.peg.743
RefSeq: NP_215182.1
TubercuList: Rv0668
MTB Network Portal: Rv0668
UniProt: P9WGY7

Orthologues for Rv0668

Species % Identity % Coverage Clones Proteins Structures
thermoresistibile 91 100 1 0 0

Enzyme & Pathway Information

Pathway Pathway ID EC Number
2.7.7.6

Sequences

These sequences are the native gene sequence; sequences of constructs derived from these sequences may differ due to codon optimization or other protocols. To find the specific sequence of any material you may have ordered, click on the "more" button next to the name of that material.
AA Sequence
MLDVNFFDEL RIGLATAEDI RQWSYGEVKK PETINYRTLK PEKDGLFCEK IFGPTRDWEC YCGKYKRVRF KGIICERCGV EVTRAKVRRE RMGHIELAAP VTHIWYFKGV PSRLGYLLDL APKDLEKIIY FAAYVITSVD EEMRHNELST LEAEMAVERK AVEDQRDGEL EARAQKLEAD LAELEAEGAK ADARRKVRDG GEREMRQIRD RAQRELDRLE DIWSTFTKLA PKQLIVDENL YRELVDRYGE YFTGAMGAES IQKLIENFDI DAEAESLRDV IRNGKGQKKL RALKRLKVVA AFQQSGNSPM GMVLDAVPVI PPELRPMVQL DGGRFATSDL NDLYRRVINR NNRLKRLIDL GAPEIIVNNE KRMLQESVDA LFDNGRRGRP VTGPGNRPLK SLSDLLKGKQ GRFRQNLLGK RVDYSGRSVI VVGPQLKLHQ CGLPKLMALE LFKPFVMKRL VDLNHAQNIK SAKRMVERQR PQVWDVLEEV IAEHPVLLNR APTLHRLGIQ AFEPMLVEGK AIQLHPLVCE AFNADFDGDQ MAVHLPLSAE AQAEARILML SSNNILSPAS GRPLAMPRLD MVTGLYYLTT EVPGDTGEYQ PASGDHPETG VYSSPAEAIM AADRGVLSVR AKIKVRLTQL RPPVEIEAEL FGHSGWQPGD AWMAETTLGR VMFNELLPLG YPFVNKQMHK KVQAAIINDL AERYPMIVVA QTVDKLKDAG FYWATRSGVT VSMADVLVPP RKKEILDHYE ERADKVEKQF QRGALNHDER NEALVEIWKE ATDEVGQALR EHYPDDNPII TIVDSGATGN FTQTRTLAGM KGLVTNPKGE FIPRPVKSSF REGLTVLEYF INTHGARKGL ADTALRTADS GYLTRRLVDV SQDVIVREHD CQTERGIVVE LAERAPDGTL IRDPYIETSA YARTLGTDAV DEAGNVIVER GQDLGDPEID ALLAAGITQV KVRSVLTCAT STGVCATCYG RSMATGKLVD IGEAVGIVAA QSIGEPGTQL TMRTFHQGGV GEDITGGLPR VQELFEARVP RGKAPIADVT GRVRLEDGER FYKITIVPDD GGEEVVYDKI SKRQRLRVFK HEDGSERVLS DGDHVEVGQQ LMEGSADPHE VLRVQGPREV QIHLVREVQE VYRAQGVSIH DKHIEVIVRQ MLRRVTIIDS GSTEFLPGSL IDRAEFEAEN RRVVAEGGEP AAGRPVLMGI TKASLATDSW LSAASFQETT RVLTDAAINC RSDKLNGLKE NVIIGKLIPA GTGINRYRNI AVQPTEEARA AAYTIPSYED QYYSPDFGAA TGAAVPLDDY GYSDYR

NT Sequence
gtgctcgacg tcaacttctt cgatgaactc cgcatcggtc ttgctaccgc ggaggacatc aggcaatggt cctatggcga ggtcaaaaag ccggagacga tcaactaccg cacgcttaag ccggagaagg acggcctgtt ctgcgagaag atcttcgggc cgactcgcga ctgggaatgc tactgcggca agtacaagcg ggtgcgcttc aagggcatca tctgcgagcg ctgcggcgtc gaggtgaccc gcgccaaggt gcgtcgtgag cggatgggcc acatcgagct tgccgcgccc gtcacccaca tctggtactt caagggtgtg ccctcgcggc tggggtatct gctggacctg gccccgaagg acctggagaa gatcatctac ttcgctgcct acgtgatcac ctcggtcgac gaggagatgc gccacaatga gctctccacg ctcgaggccg aaatggcggt ggagcgcaag gccgtcgaag accagcgcga cggcgaacta gaggcccggg cgcaaaagct ggaggccgac ctggccgagc tggaggccga gggcgccaag gccgatgcgc ggcgcaaggt tcgcgacggc ggcgagcgcg agatgcgcca gatccgtgac cgcgcgcagc gtgagctgga ccggttggag gacatctgga gcactttcac caagctggcg cccaagcagc tgatcgtcga cgaaaacctc taccgcgaac tcgtcgaccg ctacggcgag tacttcaccg gtgccatggg cgcggagtcg atccagaagc tgatcgagaa cttcgacatc gacgccgaag ccgagtcgct gcgggatgtc atccgaaacg gcaaggggca gaagaagctt cgcgccctca agcggctgaa ggtggttgcg gcgttccaac agtcgggcaa ctcgccgatg ggcatggtgc tcgacgccgt cccggtgatc ccgccggagc tgcgcccgat ggtgcagctc gacggcggcc ggttcgccac gtccgacttg aacgacctgt accgcagggt gatcaaccgc aacaaccggc tgaaaaggct gatcgatctg ggtgcgccgg aaatcatcgt caacaacgag aagcggatgc tgcaggaatc cgtggacgcg ctgttcgaca atggccgccg cggccggccc gtcaccgggc cgggcaaccg tccgctcaag tcgctttccg atctgctcaa gggcaagcag ggccggttcc ggcagaacct gctcggcaag cgtgtcgact actcgggccg gtcggtcatc gtggtcggcc cgcagctcaa gctgcaccag tgcggtctgc ccaagctgat ggcgctggag ctgttcaagc cgttcgtgat gaagcggctg gtggacctca accatgcgca gaacatcaag agcgccaagc gcatggtgga gcgccagcgc ccccaagtgt gggatgtgct cgaagaggtc atcgccgagc acccggtgtt gctgaaccgc gcacccaccc tgcaccggtt gggtatccag gccttcgagc caatgctggt ggaaggcaag gccattcagc tgcacccgtt ggtgtgtgag gcgttcaatg ccgacttcga cggtgaccag atggccgtgc acctgccttt gagcgccgaa gcgcaggccg aggctcgcat tttgatgttg tcctccaaca acatcctgtc gccggcatct gggcgtccgt tggccatgcc gcggctggac atggtgaccg ggctgtacta cctgaccacc gaggtccccg gggacaccgg cgaataccag ccggccagcg gggatcaccc ggagactggt gtctactctt cgccggccga agcgatcatg gcggccgacc gcggtgtctt gagcgtgcgg gccaagatca aggtgcggct gacccagctg cggccgccgg tcgagatcga ggccgagcta ttcggccaca gcggctggca gccgggcgat gcgtggatgg ccgagaccac gctgggccgg gtgatgttca acgagctgct gccgctgggt tatccgttcg tcaacaagca gatgcacaag aaggtgcagg ccgccatcat caacgacctg gccgagcgtt acccgatgat cgtggtcgcc cagaccgtcg acaagctcaa ggacgccggc ttctactggg ccacccgcag cggcgtgacg gtgtcgatgg ccgacgtgct ggtgccgccg cgcaagaagg agatcctcga ccactacgag gagcgcgcgg acaaggtcga aaagcagttc cagcgtggcg ctttgaacca cgacgagcgc aacgaggcgc tggtggagat ttggaaggaa gccaccgacg aggtcggtca ggcgttgcgg gagcactacc ccgacgacaa cccgatcatc accatcgtcg actccggcgc caccggcaac ttcacccaga ctcgaacgct ggccggtatg aagggcctgg tgaccaaccc gaagggtgag ttcatcccgc gtccggtcaa gtcctccttc cgtgagggcc tgaccgtgct ggagtacttc atcaacaccc acggcgctcg aaagggcttg gcggacaccg cgttgcgcac cgccgactcc ggctacctga cccgacgtct ggtggacgtg tcccaggacg tgatcgtgcg cgagcacgac tgccagaccg agcgcggcat cgtcgtcgag ctggccgagc gtgcacccga cggcacgctg atccgcgacc cgtacatcga aacctcggcc tacgcgcgga ccctgggcac cgacgcggtc gacgaggccg gcaacgtcat cgtcgagcgt ggtcaagacc tgggcgatcc ggagattgac gctctgttgg ctgctggtat tacccaggtc aaggtgcgtt cggtgctgac gtgtgccacc agcaccggcg tgtgcgcgac ctgctacggg cgttccatgg ccaccggcaa gctggtcgac atcggtgaag ccgtcggcat cgtggccgcc cagtccatcg gcgaacccgg cacccagctg accatgcgca ccttccacca gggtggcgtc ggtgaggaca tcaccggtgg tctgccccgg gtgcaggagc tgttcgaggc ccgggtaccg cgtggcaagg cgccgatcgc cgacgtcacc ggccgggttc ggctcgagga cggcgagcgg ttctacaaga tcaccatcgt tcctgacgac ggcggtgagg aagtggtcta cgacaagatc tccaagcggc agcggctgcg ggtgttcaag cacgaagacg gttccgaacg ggtgctctcc gatggcgacc acgtcgaggt gggccagcag ctgatggaag gctcggccga cccgcatgag gtgctgcggg tgcagggccc ccgcgaggtg cagatacacc tggttcgcga ggtccaggag gtctaccgcg cccaaggtgt gtcgatccac gacaagcaca tcgaggtgat cgttcgccag atgctgcgcc gggtgaccat catcgactcg ggctcgacgg agtttttgcc tggctcgctg atcgaccgcg cggagttcga ggcagagaac cgccgagtgg tggccgaggg cggtgagccc gcggccggcc gtccggtgct gatgggcatc acgaaggcgt cgctggccac cgactcgtgg ctgtcggcgg cgtcgttcca ggagaccact cgcgtgctga ccgatgcggc gatcaactgc cgcagcgata agctcaacgg tctgaaggaa aacgtgatca tcggcaagct gatcccggcc ggtaccggta tcaaccgcta ccgcaacatc gcggtgcagc ccaccgagga ggcccgcgct gcggcgtaca ccatcccgtc gtatgaggat cagtactaca gcccggactt cggtgcggcc accggtgctg ccgtcccgct ggacgactac ggctacagcg actaccgcta g

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