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Seattle Structural Genomics Center for Infectious Disease

MytuD.17861.a: DNA-directed RNA polymerase subunit beta Rv0667

Target Characteristics

from organism: Mycobacterium tuberculosis H37Rv
most recent status: purified
center reference id: MytuD.17861.a
is community request: True
associated disease: Tuberculosis
NIH risk group: 2
is select agent: False
NIH priority
pathogens category:
IIIC

Ordering Clones & Proteins

If there are materials available for this target, they will be listed below. Materials can be ordered from SSGCID using the button in the "order material" column. Clicking the button will add the material to a virtual cart. You may order multiple materials at a time at no cost to you, as this contract is funded by NIAID. When you are ready to place your order, click the "Place Order" link which will appear in the top right corner of the page after you place your first item in your cart.

External Resources

Resource Reference ID
OrthoMCL: OG5_130697
PATRIC ID: fig|83332.12.peg.742
RefSeq: NP_215181.1
TubercuList: Rv0667
MTB Network Portal: Rv0667
UniProt: P9WGY9

Orthologues for Rv0667

Species % Identity % Coverage Clones Proteins Structures
fortuitum 99 7 0 0 0
abscessus 98 11 0 0 0
fortuitum 98 11 0 0 0
abscessus 98 9 0 0 0
fortuitum 98 9 0 0 0
abscessus 97 9 0 0 0
fortuitum 97 9 0 0 0
abscessus 96 12 1 0 0
abscessus 96 9 0 0 0
abscessus 96 9 0 0 0
fortuitum 95 9 0 0 0
fortuitum 94 20 0 0 0
fortuitum 94 20 0 0 0
fortuitum 94 20 0 0 0
fortuitum 94 20 0 0 0
fortuitum 94 5 0 0 0
fortuitum 93 20 0 0 0
thermoresistibile 89 100 0 0 0
fortuitum 88 21 0 0 0
fortuitum 88 21 1 0 0
fortuitum 88 20 0 0 0
fortuitum 87 20 0 0 0
fortuitum 87 20 0 0 0
fortuitum 87 20 0 0 0
fortuitum 87 19 0 0 0
fortuitum 87 19 1 0 0
fortuitum 87 19 1 0 0
abscessus 86 21 2 0 0
fortuitum 86 19 0 0 0
thermoresistibile 86 19 1 0 0
abscessus 85 21 0 0 0
abscessus 85 21 1 0 0
abscessus 85 20 1 0 0
abscessus 85 20 0 0 0
fortuitum 85 17 1 0 0
abscessus 84 20 0 0 0
abscessus 84 19 0 0 0
abscessus 84 19 1 0 0
abscessus 84 19 0 0 0
abscessus 83 19 1 0 0
abscessus 83 18 0 0 0
abscessus 83 18 1 0 0

Enzyme & Pathway Information

Pathway Pathway ID EC Number
2.7.7.6

Sequences

These sequences are the native gene sequence; sequences of constructs derived from these sequences may differ due to codon optimization or other protocols. To find the specific sequence of any material you may have ordered, click on the "more" button next to the name of that material.
AA Sequence
MLEGCILADS RQSKTAASPS PSRPQSSSNN SVPGAPNRVS FAKLREPLEV PGLLDVQTDS FEWLIGSPRW RESAAERGDV NPVGGLEEVL YELSPIEDFS GSMSLSFSDP RFDDVKAPVD ECKDKDMTYA APLFVTAEFI NNNTGEIKSQ TVFMGDFPMM TEKGTFIING TERVVVSQLV RSPGVYFDET IDKSTDKTLH SVKVIPSRGA WLEFDVDKRD TVGVRIDRKR RQPVTVLLKA LGWTSEQIVE RFGFSEIMRS TLEKDNTVGT DEALLDIYRK LRPGEPPTKE SAQTLLENLF FKEKRYDLAR VGRYKVNKKL GLHVGEPITS STLTEEDVVA TIEYLVRLHE GQTTMTVPGG VEVPVETDDI DHFGNRRLRT VGELIQNQIR VGMSRMERVV RERMTTQDVE AITPQTLINI RPVVAAIKEF FGTSQLSQFM DQNNPLSGLT HKRRLSALGP GGLSRERAGL EVRDVHPSHY GRMCPIETPE GPNIGLIGSL SVYARVNPFG FIETPYRKVV DGVVSDEIVY LTADEEDRHV VAQANSPIDA DGRFVEPRVL VRRKAGEVEY VPSSEVDYMD VSPRQMVSVA TAMIPFLEHD DANRALMGAN MQRQAVPLVR SEAPLVGTGM ELRAAIDAGD VVVAEESGVI EEVSADYITV MHDNGTRRTY RMRKFARSNH GTCANQCPIV DAGDRVEAGQ VIADGPCTDD GEMALGKNLL VAIMPWEGHN YEDAIILSNR LVEEDVLTSI HIEEHEIDAR DTKLGAEEIT RDIPNISDEV LADLDERGIV RIGAEVRDGD ILVGKVTPKG ETELTPEERL LRAIFGEKAR EVRDTSLKVP HGESGKVIGI RVFSREDEDE LPAGVNELVR VYVAQKRKIS DGDKLAGRHG NKGVIGKILP VEDMPFLADG TPVDIILNTH GVPRRMNIGQ ILETHLGWCA HSGWKVDAAK GVPDWAARLP DELLEAQPNA IVSTPVFDGA QEAELQGLLS CTLPNRDGDV LVDADGKAML FDGRSGEPFP YPVTVGYMYI MKLHHLVDDK IHARSTGPYS MITQQPLGGK AQFGGQRFGE MECWAMQAYG AAYTLQELLT IKSDDTVGRV KVYEAIVKGE NIPEPGIPES FKVLLKELQS LCLNVEVLSS DGAAIELREG EDEDLERAAA NLGINLSRNE SASVEDLA

NT Sequence
gtgctggaag gatgcatctt ggcagattcc cgccagagca aaacagccgc tagtcctagt ccgagtcgcc cgcaaagttc ctcgaataac tccgtacccg gagcgccaaa ccgggtctcc ttcgctaagc tgcgcgaacc acttgaggtt ccgggactcc ttgacgtcca gaccgattcg ttcgagtggc tgatcggttc gccgcgctgg cgcgaatccg ccgccgagcg gggtgatgtc aacccagtgg gtggcctgga agaggtgctc tacgagctgt ctccgatcga ggacttctcc gggtcgatgt cgttgtcgtt ctctgaccct cgtttcgacg atgtcaaggc acccgtcgac gagtgcaaag acaaggacat gacgtacgcg gctccactgt tcgtcaccgc cgagttcatc aacaacaaca ccggtgagat caagagtcag acggtgttca tgggtgactt cccgatgatg accgagaagg gcacgttcat catcaacggg accgagcgtg tggtggtcag ccagctggtg cggtcgcccg gggtgtactt cgacgagacc attgacaagt ccaccgacaa gacgctgcac agcgtcaagg tgatcccgag ccgcggcgcg tggctcgagt ttgacgtcga caagcgcgac accgtcggcg tgcgcatcga ccgcaaacgc cggcaaccgg tcaccgtgct gctcaaggcg ctgggctgga ccagcgagca gattgtcgag cggttcgggt tctccgagat catgcgatcg acgctggaga aggacaacac cgtcggcacc gacgaggcgc tgttggacat ctaccgcaag ctgcgtccgg gcgagccccc gaccaaagag tcagcgcaga cgctgttgga aaacttgttc ttcaaggaga agcgctacga cctggcccgc gtcggtcgct ataaggtcaa caagaagctc gggctgcatg tcggcgagcc catcacgtcg tcgacgctga ccgaagaaga cgtcgtggcc accatcgaat atctggtccg cttgcacgag ggtcagacca cgatgaccgt tccgggcggc gtcgaggtgc cggtggaaac cgacgacatc gaccacttcg gcaaccgccg cctgcgtacg gtcggcgagc tgatccaaaa ccagatccgg gtcggcatgt cgcggatgga gcgggtggtc cgggagcgga tgaccaccca ggacgtggag gcgatcacac cgcagacgtt gatcaacatc cggccggtgg tcgccgcgat caaggagttc ttcggcacca gccagctgag ccaattcatg gaccagaaca acccgctgtc ggggttgacc cacaagcgcc gactgtcggc gctggggccc ggcggtctgt cacgtgagcg tgccgggctg gaggtccgcg acgtgcaccc gtcgcactac ggccggatgt gcccgatcga aacccctgag gggcccaaca tcggtctgat cggctcgctg tcggtgtacg cgcgggtcaa cccgttcggg ttcatcgaaa cgccgtaccg caaggtggtc gacggcgtgg ttagcgacga gatcgtgtac ctgaccgccg acgaggagga ccgccacgtg gtggcacagg ccaattcgcc gatcgatgcg gacggtcgct tcgtcgagcc gcgcgtgctg gtccgccgca aggcgggcga ggtggagtac gtgccctcgt ctgaggtgga ctacatggac gtctcgcccc gccagatggt gtcggtggcc accgcgatga ttcccttcct ggagcacgac gacgccaacc gtgccctcat gggggcaaac atgcagcgcc aggcggtgcc gctggtccgt agcgaggccc cgctggtggg caccgggatg gagctgcgcg cggcgatcga cgcggcgacg tcgtcgtcgc aagaaagcgg cgtcatcgag gaggtgtcgg ccgactacat cactgtgatg cacgacaacg gcacccggcg tacctaccgg atgcgcaagt ttgcccggtc caaccacggc acttgcgcca accagtgccc catcgtggac gcgggcgacc gagtcgaggc cggtcaggtg atcgccgacg gtccctgtac tgacgacggc gagatggcgc tgggcaagaa cctgctggtg gccatcatgc cgtgggaggg ccacaactac gaggacgcga tcatcctgtc caaccgcctg gtcgaagagg acgtgctcac ctcgatccac atcgaggagc atgagatcga tgctcgcgac accaagctgg gtgcggagga gatcacccgc gacatcccga acatctccga cgaggtgctc gccgacctgg atgagcgggg catcgtgcgc atcggtgccg aggttcgcga cggggacatc ctggtcggca aggtcacccc gaagggtgag accgagctga cgccggagga gcggctgctg cgtgccatct tcggtgagaa ggcccgcgag gtgcgcgaca cttcgctgaa ggtgccgcac ggcgaatccg gcaaggtgat cggcattcgg gtgttttccc gcgaggacga ggacgagttg ccggccggtg tcaacgagct ggtgcgtgtg tatgtggctc agaaacgcaa gatctccgac ggtgacaagc tggccggccg gcacggcaac aagggcgtga tcggcaagat cctgccggtt gaggacatgc cgttccttgc cgacggcacc ccggtggaca ttattttgaa cacccacggc gtgccgcgac ggatgaacat cggccagatt ttggagaccc acctgggttg gtgtgcccac agcggctgga aggtcgacgc cgccaagggg gttccggact gggccgccag gctgcccgac gaactgctcg aggcgcatgc gaacgccatt gtgtcgacgc cggtgttcga cggcgcccag gaggccgagc tgcagggcct gttgtcgtgc acgctgccca accgcgacgg tgacgtgctg gtcgacgccg acggcaaggc catgctcttc gacgggcgca gcggcgagcc gttcccgtac ccggtcacgg ttggctacat gtacatcatg aagctgcacc acctggtgga cgacaagatc cacgcccgct ccaccgggcc gtactcgatg atcacccagc agccgctggg cggtaaggcg cagttcggtg gccagcggtt cggggagatg gagtgctggg ccatgcaggc ctacggtgct gcctacaccc tgcaggagct gttgaccatc aagtccgatg acaccgtcgg ccgcgtcaag gtgtacgagg cgatcgtcaa gggtgagaac atcccggagc cgggcatccc cgagtcgttc aaggtgctgc tcaaagaact gcagtcgctg tgcctcaacg tcgaggtgct atcgagtgac ggtgcggcga tcgaactgcg cgaaggtgag gacgaggacc tggagcgggc cgcggccaac ctgggaatca atctgtcccg caacgaatcc gcaagtttcg aggatcttgc gtaa

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