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Seattle Structural Genomics Center for Infectious Disease

MytuD.18359.a: PE-PGRS FAMILY PROTEIN

Target Characteristics

from organism: Mycobacterium tuberculosis H37Rv
most recent status: expressed
center reference id: MytuD.18359.a
is community request: True
associated disease: Tuberculosis
NIH risk group: 2
is select agent: False
NIH priority
pathogens category:
IIIC

Ordering Clones & Proteins

If there are materials available for this target, they will be listed below. Materials can be ordered from SSGCID using the button in the "order material" column. Clicking the button will add the material to a virtual cart. You may order multiple materials at a time at no cost to you, as this contract is funded by NIAID. When you are ready to place your order, click the "Place Order" link which will appear in the top right corner of the page after you place your first item in your cart.

External Resources

Resource Reference ID
OrthoMCL: OG5_129879
PATRIC ID: fig|83332.12.peg.843
RefSeq: YP_177752
TubercuList: Rv0754
MTB Network Portal: Rv0754
UniProt: Q79FW5

Enzyme & Pathway Information

Pathway Pathway ID EC Number
homolactic fermentation ANAEROFRUCAT-PWY 5.4.2.12
glycolysis III (from glucose) ANAGLYCOLYSIS-PWY 5.4.2.12
gluconeogenesis I GLUCONEO-PWY 5.4.2.12
glycolysis I (from glucose 6-phosphate) GLYCOLYSIS 5.4.2.12
superpathway of glycolysis and the Entner-Doudoroff pathway GLYCOLYSIS-E-D 5.4.2.12
superpathway of glycolysis, pyruvate dehydrogenase, TCA, and glyoxylate bypass GLYCOLYSIS-TCA-GLYOX-BYPASS 5.4.2.12
superpathway of hexitol degradation (bacteria) HEXITOLDEGSUPER-PWY 5.4.2.12
Bifidobacterium shunt P124-PWY 5.4.2.12
glycolysis V (Pyrococcus) P341-PWY 5.4.2.12
superpathway of N-acetylneuraminate degradation P441-PWY 5.4.2.12
hexitol fermentation to lactate, formate, ethanol and acetate P461-PWY 5.4.2.12
glycolysis IV (plant cytosol) PWY-1042 5.4.2.12
Entner-Doudoroff pathway III (semi-phosphorylative) PWY-2221 5.4.2.12
superpathway of cytosolic glycolysis (plants), pyruvate dehydrogenase and TCA cycle PWY-5464 5.4.2.12
glycolysis II (from fructose 6-phosphate) PWY-5484 5.4.2.12
Rubisco shunt PWY-5723 5.4.2.12
gluconeogenesis II (Methanobacterium thermoautotrophicum) PWY-6142 5.4.2.12
Methanobacterium thermoautotrophicum biosynthetic metabolism PWY-6146 5.4.2.12
1-butanol autotrophic biosynthesis (engineered) PWY-6886 5.4.2.12
superpathway of glucose and xylose degradation PWY-6901 5.4.2.12
glycerol degradation to butanol PWY-7003 5.4.2.12
ethylene biosynthesis V (engineered) PWY-7124 5.4.2.12
photosynthetic 3-hydroxybutanoate biosynthesis (engineered) PWY-7218 5.4.2.12
superpathway of anaerobic sucrose degradation PWY-7345 5.4.2.12

Sequences

These sequences are the native gene sequence; sequences of constructs derived from these sequences may differ due to codon optimization or other protocols. To find the specific sequence of any material you may have ordered, click on the "more" button next to the name of that material.
AA Sequence
MSFVIVARDA LAAAAADLAQ IGSAVNAGNL AAANPTTAVA AAAADEVSAA LAALFGAHAR EYQAAAAQAA AYHEQFVHRL SAAATSYAVT EVTIATSLRG ALGSAPASVS DGFQAFVYGP IHATGQQWIN SPVGEALAPI VNAPTNVLLG RDLIGNGVTG TAAAPNGGPG GLLFGDGGAG YTGGNGGSAG LIGNGGTGGA GFAGGVGGMG GTGGWLMGNG GMGGAGGVGG NGGAGGQALL FGNGGLGGAG GAGGVDGAIG RGGWFIGTGG MATIGGGGNG QSIVIDFVRH GQTPGNAAML IDTAVPGPGL TALGQQQAQA IANALAAKGP YAGIFDSQLI RTQQTAAPLA NLLGMAPQVL PGLNEIHAGI FEDLPQISPA GLLYLVGPIA WTLGFPIVPM LAPGSTDVNG IVFNRAFTGA VQTIYDASLA NPVVAADGNI TSVAYSSAFT IGVGTMMNVD NPHPLLLLTH PVPNTGAVVV QGNPEGGWTL VSWDGIPVGP ASLPTALFVD VRELITAPQY AAYDIWESLF TGDPAAVINA VRDGADEVGA AVVQFPHAVA DDVIDATGHP YLSGLPIGLP SLIP

NT Sequence
atgtcatttg tgatcgtggc gcgggacgcg ttggcggcgg ccgcggcgga tctagcgcag atcggttcgg cagtgaatgc gggcaatctg gccgcagcca atccgacgac cgctgtggcg gcggcggccg ccgacgaggt atcggcggca ctcgcggcgc tgttcggcgc gcatgcccgg gagtatcagg cggcggcggc gcaggcagcg gcgtatcacg agcagtttgt gcaccgattg agcgcggcag cgacatcgta tgcggttacc gaggtgacca tcgcgacgtc gctccggggg gcgctgggct cggcgcccgc gtccgtttcc gacgggttcc aagcgttcgt ctatggtccg attcacgcga ccggccagca atggatcaac agcccggtcg gcgaggcgct cgccccgatt gtcaatgcgc cgacaaacgt gctgctcggc cgcgatctga tcggcaacgg cgtcaccggg acggcggcag ctcccaacgg tggccccggc ggtttgctat tcggtgacgg tggggccggc tataccggcg gtaacggtgg gagtgccggg ttaatcggca acgggggtac cggtggcgcc ggctttgccg gcggagtggg cggcatgggc ggcaccggcg gctggttgat gggcaacggc ggcatgggtg gcgcgggcgg tgtcggcggt aacggcggcg ccgggggcca ggcgctgttg ttcggcaacg gcggcctggg cggagccggc ggggctggcg gggtcgatgg ggctatcggt cgtggcgggt ggttcatcgg taccggcggc atggccacga tcggtggtgg cggcaacggg cagtcgatcg tcatcgactt cgtgcggcac ggccagacgc cgggcaacgc cgcaatgttg atcgacacgg cggtgcccgg acccggactc accgcgctgg gccagcaaca ggcgcaggcc atcgccaacg cgctcgcggc caagggcccc tatgccggga tcttcgactc gcagttgatc agaacgcagc agaccgccgc gccgttggcg aacttgctgg ggatggcccc gcaggtattg cccgggctca acgagatcca tgccggcatc ttcgaggacc tgccgcagat cagccccgcg ggcctgctgt atctcgtcgg cccgatcgcc tggacgctcg gatttcccat cgtgccgatg ctggccccgg gctccaccga cgtcaacggg atcgtcttca accgagcctt taccggtgcg gttcaaacga tctacgacgc ttccttggcc aatccggtcg tggccgcaga cggcaacatc acgtcggtcg cttactccag cgcattcacc atcggggtcg ggacgatgat gaacgtcgac aatccccatc cgctactgct gctcacccac ccggtgccca acaccggcgc cgtcgtggta cagggcaatc ccgagggcgg ctggacgctg gtcagctggg acgggatacc cgtcgggccg gcgtcgctgc cgaccgcgtt attcgtcgac gtgcgcgagc tgatcacggc gccgcaatat gcggcctacg acatttggga gtccctgttc accggcgatc cggcggcggt catcaacgcg gtgcgagacg gtgccgatga ggtcggcgcg gctgtggtcc agttcccaca tgcggtggct gacgacgtga tcgacgctac gggccacccc tatctaagcg gcctgccgat cggtctgccc agcctgatcc catga

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