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Seattle Structural Genomics Center for Infectious Disease

MyulA.00725.a: 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase (IspE)

Target Characteristics

from organism: Mycobacterium ulcerans Agy99
most recent status: cloned
center reference id: MyulA.00725.a
is community request: True
associated disease: Buruli, Bairnsdale ulcer
NIH risk group: 2
is select agent: False
NIH priority
pathogens category:
IIIC

Ordering Clones & Proteins

If there are materials available for this target, they will be listed below. Materials can be ordered from SSGCID using the button in the "order material" column. Clicking the button will add the material to a virtual cart. You may order multiple materials at a time at no cost to you, as this contract is funded by NIAID. When you are ready to place your order, click the "Place Order" link which will appear in the top right corner of the page after you place your first item in your cart.

Clones*

CENTER
REFERENCE ID
DOMAIN/REGION
DESCRIPTION
INFO AA
START
AA
STOP
ORDER
MATERIAL
MyulA.00725.a.B1.GE40304 Full length( MyulA.00725.a ) 1 307 GE40304
* SSGCID clones represent un-induced expression constructs which have been verified by sequencing from vector primers. Clones may contain a tag, such as N-term 6xHis. Get sequence information using the button in the "info" column.

External Resources

Resource Reference ID
OrthoMCL: OG5_130885
PATRIC ID: fig|362242.7.peg.5372
RefSeq: YP_908059.1
UniProt: A0PW69

Enzyme & Pathway Information

Pathway Pathway ID EC Number
methylerythritol phosphate pathway I NONMEVIPP-PWY 2.7.1.148
superpathway of geranylgeranyl diphosphate biosynthesis II (via MEP) PWY-5121 2.7.1.148
isoprene biosynthesis I PWY-6270 2.7.1.148
superpathway of ergosterol biosynthesis II PWY-7156 2.7.1.148
taxadiene biosynthesis (engineered) PWY-7392 2.7.1.148
methylerythritol phosphate pathway II PWY-7560 2.7.1.148

Sequences

These sequences are the native gene sequence; sequences of constructs derived from these sequences may differ due to codon optimization or other protocols. To find the specific sequence of any material you may have ordered, click on the "more" button next to the name of that material.
AA Sequence
MPTGSATVRV PGKVNLYLAV GDRRDDGYHE LTTVFHAVSL VDEVTVRNAD LLSLEVVGEG ADKLPTDKRN LAWQAAELMA EHVGRAPDVS IFIDKSIPVA GGMAGGSADA AAVLVAMNSL WELNLPRRDL RMLAAQLGSD VPFALHGGTA LGTGRGEELA TVLSRNTFHW VLAFARSGLS TPAVFTELDR LRDVGSPPRL AEPGPVLAAL AAGDPEQLAP LLGNEMQAAA VSLDPALRRA LRAGVEAGAL AGIVSGSGPT CAFLCRTAES ALDVSAQLSG AGVCRTVRIA TGPVPGARVV PTPGTPE

NT Sequence
GTGCCTACCG GGTCGGCGAC CGTAAGGGTC CCCGGCAAGG TCAACCTGTA CCTGGCGGTC GGCGATCGCC GCGATGACGG CTATCACGAG TTGACCACGG TGTTTCACGC GGTCTCCCTG GTCGACGAGG TGACGGTGCG CAACGCCGAC CTGCTGTCGC TGGAGGTCGT CGGCGAGGGC GCCGACAAAC TGCCCACCGA CAAACGCAAC CTCGCCTGGC AGGCGGCCGA GCTGATGGCC GAACACGTCG GCCGCGCACC GGACGTGTCG ATCTTCATCG ACAAGTCGAT TCCGGTGGCC GGCGGCATGG CCGGGGGCAG CGCCGACGCG GCCGCGGTAC TGGTGGCGAT GAATTCGCTG TGGGAGCTCA ACCTGCCCCG GCGTGACCTG CGCATGCTGG CCGCGCAGCT GGGCAGTGAT GTGCCCTTTG CGCTGCACGG CGGTACCGCG CTGGGCACGG GCCGCGGCGA GGAACTGGCG ACGGTCTTGT CCCGGAATAC CTTCCACTGG GTGCTGGCGT TCGCACGCAG TGGCCTGTCC ACCCCGGCGG TGTTCACCGA GCTGGACCGG CTCAGGGACG TGGGGAGTCC ACCTCGGCTC GCCGAGCCCG GGCCGGTGCT GGCGGCTCTG GCGGCCGGCG ATCCCGAGCA GCTGGCGCCC CTGCTGGGTA ACGAGATGCA GGCCGCCGCG GTGAGCCTGG ACCCGGCGCT GCGCCGGGCG CTGCGTGCCG GGGTGGAGGC CGGCGCCCTC GCCGGCATCG TCTCGGGCTC CGGTCCGACG TGTGCCTTCC TGTGCCGCAC GGCCGAGTCC GCGCTGGATG TCAGCGCGCA GCTGTCGGGA GCGGGCGTCT GTCGTACCGT TCGAATCGCC ACCGGACCGG TGCCGGGAGC CCGGGTGGTG CCGACGCCGG GAACCCCGGA G

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