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Seattle Structural Genomics Center for Infectious Disease

MyulA.01212.a: Malate dehydrogenase

Target Characteristics

from organism: Mycobacterium ulcerans Agy99
most recent status: cloned
center reference id: MyulA.01212.a
is community request: False
associated disease: Buruli, Bairnsdale ulcer
NIH risk group: 2
is select agent: False
NIH priority
pathogens category:
IIIC

Ordering Clones & Proteins

If there are materials available for this target, they will be listed below. Materials can be ordered from SSGCID using the button in the "order material" column. Clicking the button will add the material to a virtual cart. You may order multiple materials at a time at no cost to you, as this contract is funded by NIAID. When you are ready to place your order, click the "Place Order" link which will appear in the top right corner of the page after you place your first item in your cart.

External Resources

Resource Reference ID
OrthoMCL: OG5_127410
PATRIC ID: fig|362242.7.peg.5214
RefSeq: YP_907941.1
UniProt: A0PVV1

Enzyme & Pathway Information

Pathway Pathway ID EC Number
respiration (anaerobic) ANARESP1-PWY 1.1.1.37
mixed acid fermentation FERMENTATION-PWY 1.1.1.37
gluconeogenesis I GLUCONEO-PWY 1.1.1.37
superpathway of glycolysis, pyruvate dehydrogenase, TCA, and glyoxylate bypass GLYCOLYSIS-TCA-GLYOX-BYPASS 1.1.1.37
glyoxylate cycle GLYOXYLATE-BYPASS 1.1.1.37
L-aspartate degradation II MALATE-ASPARTATE-SHUTTLE-PWY 1.1.1.37
TCA cycle IV (2-oxoglutarate decarboxylase) P105-PWY 1.1.1.37
pyruvate fermentation to propanoate I P108-PWY 1.1.1.37
reductive TCA cycle I P23-PWY 1.1.1.37
incomplete reductive TCA cycle P42-PWY 1.1.1.37
formaldehyde assimilation I (serine pathway) PWY-1622 1.1.1.37
L-carnitine degradation III PWY-3641 1.1.1.37
L-glutamate degradation VIII (to propanoate) PWY-5088 1.1.1.37
reductive TCA cycle II PWY-5392 1.1.1.37
superpathway of cytosolic glycolysis (plants), pyruvate dehydrogenase and TCA cycle PWY-5464 1.1.1.37
superpathway of glyoxylate cycle and fatty acid degradation PWY-561 1.1.1.37
TCA cycle II (plants and fungi) PWY-5690 1.1.1.37
partial TCA cycle (obligate autotrophs) PWY-5913 1.1.1.37
Methanobacterium thermoautotrophicum biosynthetic metabolism PWY-6146 1.1.1.37
TCA cycle III (animals) PWY66-398 1.1.1.37
gluconeogenesis III PWY66-399 1.1.1.37
methylaspartate cycle PWY-6728 1.1.1.37
TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase) PWY-6969 1.1.1.37
malate-oxaloacetate shuttle I PWY-7047 1.1.1.37
malate-oxaloacetate shuttle II PWY-7048 1.1.1.37
C4 photosynthetic carbon assimilation cycle, NAD-ME type PWY-7115 1.1.1.37
chitin degradation to ethanol PWY-7118 1.1.1.37
anaerobic energy metabolism (invertebrates, cytosol) PWY-7383 1.1.1.37
anaerobic energy metabolism (invertebrates, mitochondrial) PWY-7384 1.1.1.37
superpathway of anaerobic energy metabolism (invertebrates) PWY-7389 1.1.1.37
TCA cycle I (prokaryotic) TCA 1.1.1.37
superpathway of glyoxylate bypass and TCA TCA-GLYOX-BYPASS 1.1.1.37

Sequences

These sequences are the native gene sequence; sequences of constructs derived from these sequences may differ due to codon optimization or other protocols. To find the specific sequence of any material you may have ordered, click on the "more" button next to the name of that material.
AA Sequence
MSASPLKVAV TGAAGQIGYS LLFRLASGSL LGPDRPIELR LLEIEPALKA LEGVVMELDD CAFPLLSGVE IGSDANKIFD GANLALLVGA RPRGPGMERS DLLEANGAIF TAQGKALNEV AADDIRVGVT GNPANTNALI AMTNAPDIPR ERFSALTRLD HNRAISQLAA KTGVAVTDIK KMTIWGNHSA TQYPDLFHAE VKGKNAAEVV NDQAWIEEYF IPTVAKRGAT IIDARGASSA ASAASASVDA ARSWLLGTPA DDWVSMAVLS DGSYGVPEGL ISSFPVTTKD GNWSIVKGLE IDEFSRGRID KTAAELADER KAVTELGLI

NT Sequence
GTGAGCGCAA GTCCCCTCAA GGTTGCCGTC ACCGGTGCCG CCGGCCAGAT CGGCTACAGC CTGTTGTTCC GCCTGGCCAG CGGGTCGCTG CTGGGCCCGG ATCGTCCGAT CGAGCTCCGC CTGCTCGAGA TCGAGCCGGC GCTCAAGGCG CTCGAGGGCG TCGTGATGGA ACTTGACGAC TGTGCGTTCC CGCTGCTGTC CGGCGTGGAG ATCGGCTCGG ACGCGAACAA GATTTTCGAC GGTGCGAATC TGGCCCTGCT CGTCGGCGCG CGTCCGCGCG GTCCGGGCAT GGAGCGCAGC GACCTGCTCG AGGCCAACGG CGCGATCTTC ACCGCTCAGG GTAAGGCGCT CAACGAGGTC GCCGCGGACG ACATCCGCGT GGGAGTGACC GGTAACCCGG CCAACACCAA CGCCCTGATC GCGATGACCA ACGCCCCCGA CATCCCCCGG GAGCGGTTCT CGGCGCTGAC CCGCCTGGAC CACAACCGCG CGATCTCGCA GCTGGCCGCC AAGACCGGTG TCGCGGTCAC CGACATCAAG AAGATGACCA TCTGGGGCAA CCACTCGGCC ACCCAGTACC CCGACCTTTT CCACGCCGAA GTCAAGGGCA AGAACGCGGC CGAGGTGGTC AATGACCAGG CGTGGATCGA GGAGTACTTC ATCCCGACCG TCGCCAAGCG TGGTGCGACG ATCATCGACG CGCGCGGCGC ATCCTCGGCC GCTTCGGCCG CGTCGGCGAG CGTCGACGCA GCCCGTTCCT GGTTGCTCGG CACCCCCGCC GACGACTGGG TCTCGATGGC TGTCCTCTCC GACGGTTCCT ACGGTGTGCC CGAGGGCCTG ATCTCCTCGT TCCCGGTCAC CACGAAGGAC GGCAACTGGA GCATCGTCAA GGGCCTGGAG ATCGACGAAT TCTCCCGCGG TCGCATCGAC AAGACGGCCG CTGAACTGGC CGACGAGCGC AAGGCGGTCA CCGAGCTCGG CCTGATC

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