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Seattle Structural Genomics Center for Infectious Disease

MyulA.10611.b: Zinc-dependent alcohol dehydrogenase AdhE2

Target Characteristics

from organism: Mycobacterium ulcerans Agy99
most recent status: cloned
center reference id: MyulA.10611.b
is community request: False
associated disease: Buruli, Bairnsdale ulcer
NIH risk group: 2
is select agent: False
NIH priority
pathogens category:
IIIC

Ordering Clones & Proteins

If there are materials available for this target, they will be listed below. Materials can be ordered from SSGCID using the button in the "order material" column. Clicking the button will add the material to a virtual cart. You may order multiple materials at a time at no cost to you, as this contract is funded by NIAID. When you are ready to place your order, click the "Place Order" link which will appear in the top right corner of the page after you place your first item in your cart.

External Resources

Resource Reference ID
OrthoMCL: OG5_127257
PATRIC ID: fig|362242.7.peg.1565
RefSeq: YP_905324.1
UniProt: A0PND4

Enzyme & Pathway Information

Pathway Pathway ID EC Number
L-homoserine biosynthesis HOMOSERSYN-PWY 1.1.1.3
superpathway of S-adenosyl-L-methionine biosynthesis MET-SAM-PWY 1.1.1.3
superpathway of L-homoserine and L-methionine biosynthesis METSYN-PWY 1.1.1.3
superpathway of L-lysine, L-threonine and L-methionine biosynthesis I P4-PWY 1.1.1.3
aspartate superpathway PWY0-781 1.1.1.3
superpathway of L-isoleucine biosynthesis I PWY-3001 1.1.1.3
superpathway of L-methionine biosynthesis (by sulfhydrylation) PWY-5345 1.1.1.3
superpathway of L-methionine biosynthesis (transsulfuration) PWY-5347 1.1.1.3
superpathway of L-lysine, L-threonine and L-methionine biosynthesis II PWY-724 1.1.1.3
superpathway of L-threonine biosynthesis THRESYN-PWY 1.1.1.3
formaldehyde oxidation III (mycothiol-dependent) PWY1G-170 1.1.1.306
methanol oxidation to carbon dioxide PWY-7616 1.1.1.306
formaldehyde oxidation V (bacillithiol-dependent) PWY-7908 1.1.1.306

Sequences

These sequences are the native gene sequence; sequences of constructs derived from these sequences may differ due to codon optimization or other protocols. To find the specific sequence of any material you may have ordered, click on the "more" button next to the name of that material.
AA Sequence
MSQTVRGVIS RKKGEPVELV DIVVPDPGPG EAVVDISACG VCHTDLTYRE GGINDEYPFL LGHEAAGTVE AVGPGVTNVE PGDFVILNWR AVCGQCRACK RGRPSYCFDT FNAEQKMTLT DGTELTPALG IGAFADKTLV HSGQCTKVDP AADPAVAGLL GCGVMAGLGA AVNTGGVTRD DTVAVIGCGG VGDAAIAGAA LVGAKKIIAV DTDNTKLEWA RAFGATHTVN ARELDVVETI QDLTGGFGVD VVIDAVGRPE TWKQAFYARD LAGTVVLVGV PTPDMRLDMP LVDFFSRGGA LKSSWYGDCL PERDFPTLID LYLQGRLPLD KFVSEQIGLG GIEEAFEKMH AGKVLRSVVV L

NT Sequence
ATGAGTCAGA CAGTGCGCGG CGTAATTTCC CGGAAAAAGG GCGAACCCGT TGAATTGGTG GACATCGTCG TCCCGGATCC CGGGCCCGGC GAAGCCGTCG TCGATATCAG CGCTTGCGGC GTTTGTCACA CCGATCTGAC CTACCGCGAG GGCGGCATCA ACGACGAGTA CCCGTTCCTG TTGGGCCACG AGGCCGCGGG CACGGTCGAA GCGGTTGGGC CCGGGGTAAC CAACGTGGAG CCAGGCGATT TCGTGATCCT GAACTGGCGT GCGGTGTGCG GCCAGTGCCG GGCCTGCAAA CGGGGCCGGC CGAGCTACTG TTTCGACACG TTCAACGCCG AGCAGAAGAT GACACTGACC GACGGCACCG AACTCACCCC GGCACTGGGC ATCGGGGCAT TCGCCGACAA GACGCTGGTG CACTCCGGCC AATGCACCAA GGTTGATCCC GCGGCCGACC CCGCCGTGGC GGGCCTGTTG GGTTGCGGCG TGATGGCCGG ACTGGGCGCC GCGGTCAACA CCGGTGGCGT CACCCGCGAT GACACCGTCG CGGTGATCGG TTGTGGCGGC GTGGGTGATG CCGCCATCGC CGGTGCGGCG CTGGTCGGAG CCAAGAAAAT CATCGCCGTC GACACCGACA ACACCAAACT GGAGTGGGCG CGCGCCTTCG GCGCCACCCA CACCGTCAAC GCCCGCGAAC TCGACGTCGT CGAAACGATC CAGGACCTCA CCGGCGGCTT TGGGGTCGAC GTGGTGATCG ACGCGGTCGG CCGGCCCGAA ACCTGGAAGC AGGCGTTCTA CGCTCGCGAT CTGGCCGGAA CCGTTGTCCT GGTGGGGGTT CCCACCCCCG ACATGCGGCT GGACATGCCG CTGGTGGACT TCTTCTCCCG CGGTGGCGCG TTGAAGTCGT CCTGGTACGG CGATTGCCTA CCCGAGCGCG ACTTCCCCAC CCTGATCGAC CTCTACCTGC AGGGCCGGCT TCCGCTGGAC AAGTTCGTTT CCGAGCAGAT CGGTCTGGGC GGTATCGAGG AGGCATTCGA GAAGATGCAC GCCGGCAAGG TGCTGCGCTC GGTGGTGGTG TTG

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