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Seattle Structural Genomics Center for Infectious Disease

NafoA.00005.a: malate dehydrogenase (mitochondrial) (MDH2)

Target Characteristics

from organism: Naegleria fowleri ATCC 30863
most recent status: in PDB
center reference id: NafoA.00005.a
is community request: True
associated disease:
NIH risk group: 2
is select agent: False
NIH priority
pathogens category:
IIB

Ordering Clones & Proteins

If there are materials available for this target, they will be listed below. Materials can be ordered from SSGCID using the button in the "order material" column. Clicking the button will add the material to a virtual cart. You may order multiple materials at a time at no cost to you, as this contract is funded by NIAID. When you are ready to place your order, click the "Place Order" link which will appear in the top right corner of the page after you place your first item in your cart.

Clones*

CENTER
REFERENCE ID
DOMAIN/REGION
DESCRIPTION
INFO AA
START
AA
STOP
ORDER
MATERIAL
NafoA.00005.a.B1.GE40135 Full length(NafoA.00005.a) 1 436 GE40135
* SSGCID clones represent un-induced expression constructs which have been verified by sequencing from vector primers. Clones may contain a tag, such as N-term 6xHis. Get sequence information using the button in the "info" column.

Proteins

CENTER
REFERENCE ID
DOMAIN/REGION
DESCRIPTION
INFO AA
START
AA
STOP
ORDER
MATERIAL
NafoA.00005.a.B1.PS38166 Full length(NafoA.00005.a) 1 436

Structures

image of structure for 6UM4
6UM4
Deposited: 10/9/2019
Determination: XRay
Diffraction Image
Clone: NafoA.00005.a.B1.GE40135
Protein: NafoA.00005.a.B1.PS38166

External Resources

Resource Reference ID
EuPathDB: AmoebaDB:NF0021050

Sequences

These sequences are the native gene sequence; sequences of constructs derived from these sequences may differ due to codon optimization or other protocols. To find the specific sequence of any material you may have ordered, click on the "more" button next to the name of that material.
AA Sequence
MKRLVPQFSK SSRNGVRHYS TLKQRGEKMD AELSATRTPL ERMLLGKQTK NDFANLNIKD PKTVAQWLNK SAREGPKYLT KDVDQLAPPV TITVSGACGQ IANSLLFRIA NGEMLGENQP VKLRLLERPE AMKALEGVKM ELDDGAFPLL EEIYLTDSEN DAFRGADYAI LLGGKPRGPG MERADVMKDN AAIFKAQGEA LNKQANGDVL VLIVANPANT NAMITSANAP DIPPENITAM TRLDHDRGLA QVAAKVGCNI TDISRFAIWG NHSATQYPDL SFTTIKGQWG LNVINDEQWI TNEFIPNVQQ RGAAIIKARG KSSAASAADA AIKHMHDWVL GNSEWVSMAI PSRGQYGIPR GIWCSMPVQC FGAGKYGVIE GLPINSFSAD RINASVKELI EEKKIVENLL PNPVYRLVEV DKVNIISKSY ISENKQ

NT Sequence
ATGAAGAGAC TCGTCCCCCA ATTCTCCAAA TCTTCACGTA ATGGTGTCCG CCATTATAGC ACCTTGAAAC AAAGAGGTGA AAAGATGGAT GCCGAATTGT CTGCAACAAG AACACCACTT GAAAGAATGT TGCTTGGAAA GCAAACCAAG AACGATTTTG CCAATTTGAA CATTAAAGAT CCAAAGACAG TCGCTCAATG GTTGAACAAG AGTGCTAGAG AGGGACCAAA ATACTTGACA AAGGATGTCG ATCAATTGGC TCCTCCAGTT ACAATCACTG TCTCTGGAGC ATGTGGACAA ATTGCCAATA GCCTGTTGTT CAGAATTGCT AACGGTGAAA TGTTGGGCGA AAATCAACCA GTGAAGTTGA GATTGTTGGA AAGACCAGAA GCAATGAAGG CTCTTGAAGG AGTGAAAATG GAATTGGACG ATGGCGCTTT CCCACTCTTG GAAGAAATTT ATCTTACCGA TAGTGAAAAT GATGCTTTCA GAGGTGCTGA CTATGCTATT TTGCTCGGAG GAAAGCCAAG AGGTCCTGGA ATGGAAAGAG CTGATGTCAT GAAAGACAAT GCTGCTATTT TTAAGGCTCA AGGTGAGGCT TTGAACAAGC AAGCTAACGG AGATGTTTTG GTTTTGATTG TTGCCAATCC AGCCAACACT AACGCTATGA TTACATCTGC CAATGCTCCA GATATTCCAC CAGAAAATAT CACTGCAATG ACAAGACTTG ATCACGATAG AGGATTGGCT CAAGTTGCAG CAAAGGTTGG ATGTAATATT ACCGACATTT CACGATTTGC TATTTGGGGT AACCACTCTG CCACTCAATA TCCAGATCTT TCATTCACAA CCATCAAAGG ACAATGGGGT CTTAACGTGA TTAATGACGA ACAATGGATT ACAAATGAAT TTATTCCAAA CGTGCAACAA CGTGGTGCTG CTATCATCAA GGCCAGAGGA AAGTCAAGTG CTGCTTCTGC TGCCGACGCT GCTATTAAAC ATATGCACGA TTGGGTTTTG GGAAATAGCG AATGGGTTTC TATGGCTATT CCATCAAGAG GTCAATATGG TATCCCAAGA GGTATTTGGT GTTCAATGCC AGTGCAATGC TTTGGAGCTG GTAAATACGG AGTCATTGAA GGTTTACCAA TCAACTCCTT CAGCGCTGAT AGAATTAATG CTAGCGTAAA GGAACTTATT GAGGAAAAGA AGATTGTTGA AAATTTATTA CCAAATCCAG TTTACAGATT AGTCGAAGTT GACAAGGTTA ACATTATTAG CAAGTCATAC ATCTCAGAAA ACAAGCAA

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