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Seattle Structural Genomics Center for Infectious Disease

NafoA.18681.a: prolyl-trna synthetase

Target Characteristics

from organism: Naegleria fowleri ATCC 30863
most recent status: in PDB
center reference id: NafoA.18681.a
is community request: True
associated disease:
NIH risk group: 2
is select agent: False
NIH priority
pathogens category:
IIB

Ordering Clones & Proteins

If there are materials available for this target, they will be listed below. Materials can be ordered from SSGCID using the button in the "order material" column. Clicking the button will add the material to a virtual cart. You may order multiple materials at a time at no cost to you, as this contract is funded by NIAID. When you are ready to place your order, click the "Place Order" link which will appear in the top right corner of the page after you place your first item in your cart.

Clones*

CENTER
REFERENCE ID
DOMAIN/REGION
DESCRIPTION
INFO AA
START
AA
STOP
ORDER
MATERIAL
NafoA.18681.a.B2.GE40322 ordered domain 31 535 GE40322
NafoA.18681.a.B3.GE42995 rescue 2 28 477 GE42995
* SSGCID clones represent un-induced expression constructs which have been verified by sequencing from vector primers. Clones may contain a tag, such as N-term 6xHis. Get sequence information using the button in the "info" column.

Proteins

CENTER
REFERENCE ID
DOMAIN/REGION
DESCRIPTION
INFO AA
START
AA
STOP
ORDER
MATERIAL
NafoA.18681.a.B2.PW38711 ordered domain 31 535

Structures

image of structure for 6NAB
6NAB
Deposited: 12/5/2018
Determination: XRay
Diffraction Image
Clone: NafoA.18681.a.B2.GE40322
Protein: NafoA.18681.a.B2.PW37988
image of structure for 6UYH
6UYH
Deposited: 11/13/2019
Determination: XRay
Diffraction Image
Clone: NafoA.18681.a.B2.GE40322
Protein: NafoA.18681.a.B2.PW37988

External Resources

Resource Reference ID
EuPathDB: AmoebaDB:NF0061610

Sequences

These sequences are the native gene sequence; sequences of constructs derived from these sequences may differ due to codon optimization or other protocols. To find the specific sequence of any material you may have ordered, click on the "more" button next to the name of that material.
AA Sequence
MSDQPASSNN NKEKKSKPAK QQQQGSSSGL KQNEGIDVKK QENFSEWYSQ VITKSEFLDY YDVSGCYIFR PNCWFVWESV QKFFDAEIKK LGVQNVMFPL FVTKRALETE KDHVEGFSPE VAWVTKSGNS DLQEPIALRP TSETIMYPSY AKWIQSHRDL PLKLNQWTNV VRWEFKHAVP FIRSREFYWQ EGHSAFKSKE EADEEVFTIL ELYKRVYEEL LAVPVIKGTK TENEKFAGAD YTTTVETFIA TNGRAVQGGT SHHLGQNFSK MFKIQFEAEN KETQFAYQNS WGLSTRTLGV MIMVHGDDKG MVLPPRVAFC QVVVIPLIFK DKDNATLVEK TKEIYNELEK AGIRVKLDDR LERTPGWKYN YWELRGVPLR IEVGPKDLEK QQIMLCRRDT GEKWTMPLSE FSGDSIKAVL DKIHDSMLNK ARKEMNERIV VTRTWPEFIK ALNSGNMCLI PWHESKAAEE YIKEKSKLES VQSQSDANTG LTGAAKSLCV PLDQSSFPSL EGLENFYPEE AHKKPNCWAL FGRSY

NT Sequence
ATGTCCGATC AACCAGCATC ATCCAACAAT AACAAGGAGA AGAAATCCAA ACCAGCAAAG CAACAACAAC AAGGTTCTTC TTCTGGTCTC AAACAAAACG AAGGTATTGA TGTCAAGAAG CAAGAAAACT TTAGCGAATG GTACAGCCAA GTCATCACCA AGAGTGAATT CTTGGATTAC TATGATGTGA GTGGATGTTA TATTTTCAGA CCAAATTGTT GGTTTGTTTG GGAGTCTGTT CAAAAGTTCT TTGATGCAGA AATTAAAAAG TTGGGTGTTC AAAATGTCAT GTTTCCATTG TTTGTTACCA AGAGAGCTTT GGAAACTGAG AAGGACCACG TTGAAGGCTT CTCTCCAGAA GTTGCTTGGG TCACCAAGTC CGGTAATTCG GATCTTCAAG AACCAATTGC TTTGAGACCA ACAAGTGAAA CCATCATGTA TCCATCGTAT GCCAAGTGGA TTCAATCTCA CAGAGATTTG CCATTAAAAT TGAACCAATG GACAAACGTT GTTAGATGGG AATTTAAACA TGCTGTTCCT TTCATTAGAT CCAGAGAATT CTACTGGCAA GAAGGTCACA GTGCTTTCAA ATCAAAGGAA GAAGCTGATG AAGAAGTTTT TACTATTTTG GAGTTATATA AAAGAGTTTA CGAAGAATTG TTGGCTGTTC CAGTCATCAA GGGTACCAAG ACTGAAAATG AAAAGTTTGC TGGAGCCGAC TACACAACTA CTGTGGAAAC TTTCATTGCT ACAAACGGAA GAGCAGTACA AGGAGGTACA AGCCATCACT TGGGACAAAA TTTCTCAAAG ATGTTCAAGA TTCAATTCGA AGCTGAAAAC AAGGAGACAC AATTTGCTTA CCAAAATTCA TGGGGCTTGT CAACTCGTAC TCTCGGTGTC ATGATTATGG TTCACGGAGA TGACAAGGGT ATGGTTTTAC CACCAAGAGT TGCTTTCTGC CAAGTTGTCG TTATTCCACT CATCTTCAAG GACAAGGATA ACGCCACTTT GGTAGAAAAG ACCAAGGAAA TTTATAATGA GCTTGAAAAG GCTGGAATTC GTGTCAAGTT GGATGATCGT TTGGAGAGAA CTCCAGGTTG GAAATACAAT TATTGGGAAC TCCGTGGTGT TCCATTGCGT ATTGAAGTTG GACCAAAGGA TTTGGAAAAG CAACAAATTA TGCTCTGTAG AAGAGACACA GGAGAAAAGT GGACCATGCC ACTCAGTGAA TTTTCTGGTG ATTCCATTAA GGCCGTTCTT GATAAAATTC ATGACTCCAT GTTGAACAAG GCCAGAAAGG AAATGAATGA AAGAATTGTA GTGACAAGAA CATGGCCAGA GTTCATCAAG GCACTCAACT CTGGAAATAT GTGTCTTATT CCTTGGCATG AAAGCAAGGC AGCAGAGGAA TATATTAAGG AAAAGTCAAA GTTGGAAAGT GTCCAAAGTC AATCTGATGC CAACACAGGT TTAACAGGAG CTGCCAAATC ATTGTGTGTC CCTCTCGACC AATCTTCCTT CCCATCATTG GAAGGTCTTG AGAACTTTTA TCCTGAAGAA GCTCACAAGA AGCCAAATTG TTGGGCTTTG TTCGGTAGAA GTTAT

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