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Seattle Structural Genomics Center for Infectious Disease

RiprA.00023.a: inorganic pyrophosphatase

Target Characteristics

from organism: Rickettsia prowazekii str. Madrid E
most recent status: in PDB
center reference id: RiprA.00023.a
is community request: False
associated disease: Endemic typhus
NIH risk group: 3
is select agent: True
NIH priority
pathogens category:
IIIB/C

Ordering Clones & Proteins

If there are materials available for this target, they will be listed below. Materials can be ordered from SSGCID using the button in the "order material" column. Clicking the button will add the material to a virtual cart. You may order multiple materials at a time at no cost to you, as this contract is funded by NIAID. When you are ready to place your order, click the "Place Order" link which will appear in the top right corner of the page after you place your first item in your cart.

Clones*

CENTER
REFERENCE ID
DOMAIN/REGION
DESCRIPTION
INFO AA
START
AA
STOP
ORDER
MATERIAL
RiprA.00023.a.A1.GE25409 Full length( RiprA.00023.a ) 1 172 GE25409
* SSGCID clones represent un-induced expression constructs which have been verified by sequencing from vector primers. Clones may contain a tag, such as N-term 6xHis. Get sequence information using the button in the "info" column.

Proteins

CENTER
REFERENCE ID
DOMAIN/REGION
DESCRIPTION
INFO AA
START
AA
STOP
ORDER
MATERIAL
RiprA.00023.a.A1.PS00059 Full length( RiprA.00023.a ) 1 172

Structures

image of structure for 3D53
3D53
Deposited: 5/15/2008
Determination: XRay
Diffraction Image
Clone:
Protein: RiprA.00023.a.D11.PD00006
image of structure for 3EMJ
3EMJ
Deposited: 9/24/2008
Determination: XRay
Diffraction Image
Clone:
Protein: RiprA.00023.a.D11.PD00006

Citations by Others

Enzyme repurposing of a hydrolase as an emergent peroxidase upon metal binding
N Fujieda, J Schätti, E Stuttfeld, K Ohkubo, T Maier… - Chemical …, 2015 - pubs.rsc.org
cited by: 2 others
PDB: 3D53
Identification of two-histidines one-carboxylate binding motifs in proteins amenable to facial coordination to metals
M Schmid, G Collet, P Cuniasse, F Gilardoni? - Metallomics, 2012 - pubs.rsc.org
cited by: 6 others
PDB: 3D53

This list was obtained from Google Scholar searches using the Open Source tool https://github.com/ckreibich/scholar.py and each citation has been manually reviewed.

External Resources

Resource Reference ID
OrthoMCL: OG5_128875
PATRIC ID: fig|272947.5.peg.606
RefSeq: NP_220958
UniProt: Q9ZCW5

Enzyme & Pathway Information

Pathway Pathway ID EC Number
(aminomethyl)phosphonate degradation PWY-7805 3.6.1.1
glyphosate degradation III PWY-7807 3.6.1.1

Sequences

These sequences are the native gene sequence; sequences of constructs derived from these sequences may differ due to codon optimization or other protocols. To find the specific sequence of any material you may have ordered, click on the "more" button next to the name of that material.
AA Sequence
MFIKKIKAKA NNNEINVIIE IPMNSGPIKY EFDKESGALF VDRFMQTTMS YPCNYGFIPD TLSNDGDPVD VLVVAHHPVV PGSVIKCRAI GVLMMEDESG LDEKIIAVPT SKLDITFDHI KELDDLCEML KKRIVHFFEH YKDLEKGKWV KVTGWGDKVK AETLIKEGID RN

NT Sequence
ATGTTTATAA AGAAAATTAA AGCAAAAGCA AACAATAATG AAATAAATGT AATTATCGAA ATTCCAATGA ATAGCGGACC AATCAAATAC GAATTTGACA AAGAATCAGG TGCACTTTTT GTTGATCGTT TTATGCAAAC TACCATGAGT TATCCTTGTA ATTATGGTTT TATTCCTGAT ACTCTTTCAA ATGATGGTGA TCCGGTAGAT GTACTTGTTG TAGCACATCA TCCCGTCGTA CCTGGGTCAG TGATCAAATG CAGAGCAATA GGTGTATTAA TGATGGAAGA CGAATCAGGA CTCGATGAGA AGATTATCGC AGTACCAACA TCTAAACTCG ATATTACTTT CGATCATATT AAAGAACTAG ATGATTTATG TGAAATGCTA AAAAAACGTA TTGTGCATTT CTTTGAGCAT TATAAAGATT TAGAAAAAGG TAAATGGGTT AAAGTTACTG GATGGGGAGA TAAAGTAAAA GCAGAAACTT TAATAAAGGA AGGAATAGAC AGAAAT

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